Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_056327                                                              16    7355
NP_055979                                                              16    7355
NP_653286                                                              16    7355
XP_006723099                                                           16    7355
XP_006713163                                                           16    7355
XP_006710739                                                           16    7355
XP_005270979                                                           16    7355
XP_005245848                                                           16    7355
XP_005245847                                                           16    7355
NP_056972                                                              16    7355
NP_060250                                                              15    9605
XP_005251324                                                           15    9605
XP_005251323                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVSESMVP 9
            QAVSES VP
Sbjct: 1373 QAVSESTVP 1381
>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVSESMVP 9
            QAVSES VP
Sbjct: 1373 QAVSESTVP 1381
>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVSESMVP 9
            QAVSES VP
Sbjct: 1373 QAVSESTVP 1381
>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVSESMVP 9
            QAVSES VP
Sbjct: 1373 QAVSESTVP 1381
>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVSESMVP 9
            QAVSES VP
Sbjct: 1373 QAVSESTVP 1381
>NP_056327
          Length = 4265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AVSESMVP 9
           AVS++M+P
Sbjct: 736 AVSKAMIP 743
>NP_055979
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QAVSESMVP 9
           QAVS+ ++P
Sbjct: 870 QAVSKGVIP 878
>NP_653286
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESMVP 9
           AVS+ MVP
Sbjct: 449 AVSDMMVP 456
>XP_006723099
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESMVP 9
           AVS+ MVP
Sbjct: 449 AVSDMMVP 456
>XP_006713163
          Length = 4265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AVSESMVP 9
           AVS++M+P
Sbjct: 736 AVSKAMIP 743
>XP_006710739
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QAVSESMVP 9
           Q +SE+++P
Sbjct: 95  QQISEALIP 103
>XP_005270979
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QAVSESMVP 9
           Q +SE+++P
Sbjct: 95  QQISEALIP 103
>XP_005245848
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QAVSESMVP 9
           QAVS+ ++P
Sbjct: 667 QAVSKGVIP 675
>XP_005245847
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QAVSESMVP 9
           QAVS+ ++P
Sbjct: 850 QAVSKGVIP 858
>NP_056972
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QAVSESMVP 9
           Q +SE+++P
Sbjct: 95  QQISEALIP 103
>NP_060250
          Length = 2997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   QAVSESMVP 9
           QA+ E ++P
Sbjct: 489 QAIQERLIP 497
>XP_005251324
          Length = 2996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   QAVSESMVP 9
           QA+ E ++P
Sbjct: 489 QAIQERLIP 497
>XP_005251323
          Length = 2997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   QAVSESMVP 9
           QA+ E ++P
Sbjct: 489 QAIQERLIP 497
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.108    0.260 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 233,860
Number of extensions: 251
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package