Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
NP_001002811                                                           18    1482
NP_001002812                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
NP_612355                                                              17    3301
NP_001138909                                                           17    3301
NP_001136028                                                           17    3301
NP_036616                                                              17    3301
NP_002331                                                              17    3301
NP_001138908                                                           17    3301
NP_001136029                                                           17    3301
NP_036617                                                              17    3301
NP_001001438                                                           17    3301
XP_006726657                                                           17    3301
XP_006725285                                                           17    3301
XP_006724066                                                           17    3301
XP_005263588                                                           17    3301
NP_878918                                                              16    7355
NP_055995                                                              16    7355
NP_776194                                                              16    7355
NP_001005739                                                           16    7355
NP_057600                                                              16    7355
XP_006720147                                                           16    7355
XP_005267517                                                           16    7355
XP_005267516                                                           16    7355
XP_005267515                                                           16    7355
XP_005267514                                                           16    7355
XP_005267513                                                           16    7355
XP_005267512                                                           16    7355
XP_005267511                                                           16    7355
XP_006712092                                                           16    7355
NP_071446                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 898 QEVLLLREK 906
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 832 QEVLLLREK 840
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 832 QEVLLLREK 840
>NP_001002811
          Length = 1132

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 832 QEVLLLREK 840
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 898 QEVLLLREK 906
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 898 QEVLLLREK 906
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 898 QEVLLLREK 906
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 832 QEVLLLREK 840
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 832 QEVLLLREK 840
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 835 QEVLLLREK 843
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 898 QEVLLLREK 906
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           Q VLLLREK
Sbjct: 898 QEVLLLREK 906
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAVLLLREK 9
            Q VLLLREK
Sbjct: 995  QEVLLLREK 1003
>NP_612355
          Length = 634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   QAVLLLRE 8
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>NP_001138909
          Length = 652

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QAVLLLREK 9
           +AVLLL+EK
Sbjct: 382 KAVLLLQEK 390
>NP_001136028
          Length = 725

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QA LLL+EK
Sbjct: 437 QATLLLQEK 445
>NP_036616
          Length = 724

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QA LLL+EK
Sbjct: 436 QATLLLQEK 444
>NP_002331
          Length = 732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QAVLLLREK 9
           +AVLLL+EK
Sbjct: 462 KAVLLLQEK 470
>NP_001138908
          Length = 721

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QAVLLLREK 9
           +AVLLL+EK
Sbjct: 451 KAVLLLQEK 459
>NP_001136029
          Length = 638

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QA LLL+EK
Sbjct: 350 QATLLLQEK 358
>NP_036617
          Length = 709

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QA LLL+EK
Sbjct: 421 QATLLLQEK 429
>NP_001001438
          Length = 732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QAVLLLREK 9
           +AVLLL+EK
Sbjct: 462 KAVLLLQEK 470
>XP_006726657
          Length = 633

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   QAVLLLRE 8
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>XP_006725285
          Length = 633

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   QAVLLLRE 8
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>XP_006724066
          Length = 732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QAVLLLREK 9
           +AVLLL+EK
Sbjct: 462 KAVLLLQEK 470
>XP_005263588
          Length = 667

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   QAVLLLRE 8
           +AVLLLRE
Sbjct: 139 EAVLLLRE 146
>NP_878918
          Length = 6907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>NP_055995
          Length = 6885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>NP_776194
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV LLR++
Sbjct: 165 QAVALLRDR 173
>NP_001005739
          Length = 965

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV +LR+K
Sbjct: 238 QAVKMLRDK 246
>NP_057600
          Length = 977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV +LR+K
Sbjct: 250 QAVKMLRDK 258
>XP_006720147
          Length = 4788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267517
          Length = 6883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267516
          Length = 6884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267515
          Length = 6899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267514
          Length = 6908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267513
          Length = 6921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267512
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_005267511
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV L++EK
Sbjct: 418 QAVTLIQEK 426
>XP_006712092
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAVLLLREK 9
           QAV +LR+K
Sbjct: 250 QAVKMLRDK 258
>NP_071446
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLLLREK 9
           VLL+REK
Sbjct: 158 VLLVREK 164
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.140    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,154
Number of extensions: 606
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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