Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001274730                                                           17    2528
XP_005268043                                                           17    3301
NP_071343                                                              17    3301
NP_001073867                                                           17    4312
NP_001072983                                                           17    4312
NP_001274731                                                           17    4312
NP_003184                                                              17    4312
XP_005251911                                                           17    4312
XP_005251910                                                           17    4312
XP_005251909                                                           17    4312
XP_005251908                                                           17    4312
XP_005251907                                                           17    4312
NP_001131145                                                           16    5631
NP_703194                                                              16    5631
NP_060090                                                              16    5631
NP_036350                                                              16    5631
NP_004507                                                              16    5631
NP_001265455                                                           16    5631
NP_057195                                                              16    5631
NP_001265454                                                           16    5631
NP_001265453                                                           16    5631
NP_055618                                                              16    5631
XP_005259952                                                           16    5631
XP_006722805                                                           16    5631
XP_006721056                                                           16    5631
NP_001268901                                                           16    7355
NP_001268900                                                           16    7355
NP_003027                                                              16    7355
NP_078891                                                              16    7355
NP_001265723                                                           16    7355
NP_001171526                                                           16    7355
NP_001171527                                                           16    7355
NP_001127948                                                           16    7355
NP_056165                                                              16    7355
NP_005963                                                              16    7355
NP_660358                                                              16    7355
NP_001095841                                                           16    7355
NP_079231                                                              16    7355
NP_001017987                                                           16    7355
NP_005984                                                              16    7355
XP_006722353                                                           16    7355
XP_005256453                                                           16    7355
XP_006722333                                                           16    7355
XP_005249600                                                           16    7355
XP_005249599                                                           16    7355
XP_005266942                                                           16    7355
XP_005248654                                                           16    7355
XP_005248653                                                           16    7355
XP_005244832                                                           16    7355
XP_005270761                                                           16    7355
XP_005270760                                                           16    7355
XP_005270759                                                           16    7355
XP_006710604                                                           16    7355
XP_005270758                                                           16    7355
NP_005533                                                              16    7355
NP_001129475                                                           16    7355
NP_598377                                                              16    7355
NP_057259                                                              16    7355
NP_001191355                                                           15    9605
NP_004950                                                              15    9605
NP_620688                                                              15    9605
NP_434701                                                              15    9605
NP_434700                                                              15    9605
NP_060857                                                              15    9605
NP_001164608                                                           15    9605
NP_060282                                                              15    9605
NP_078904                                                              15    9605
NP_002305                                                              15    9605
NP_001182412                                                           15    9605
NP_055049                                                              15    9605
XP_005254929                                                           15    9605
XP_005252142                                                           15    9605
XP_005252140                                                           15    9605
XP_005251930                                                           15    9605
XP_005251929                                                           15    9605
XP_005251928                                                           15    9605
>NP_001274730
          Length = 578

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ARVLRCLA 9
           A+VLRC+A
Sbjct: 270 AKVLRCVA 277
>XP_005268043
          Length = 318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QARVLRCL 8
          +AR+L+CL
Sbjct: 8  EARILQCL 15
>NP_071343
          Length = 342

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QARVLRCL 8
          +AR+L+CL
Sbjct: 32 EARILQCL 39
>NP_001073867
          Length = 2017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RVLRCL
Sbjct: 708 RVLRCL 713
>NP_001072983
          Length = 527

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARVLRCLA 9
           A VLRC+A
Sbjct: 219 AEVLRCVA 226
>NP_001274731
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARVLRCLA 9
           A VLRC+A
Sbjct: 106 AEVLRCVA 113
>NP_003184
          Length = 527

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARVLRCLA 9
           A VLRC+A
Sbjct: 219 AEVLRCVA 226
>XP_005251911
          Length = 1839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RVLRCL
Sbjct: 530 RVLRCL 535
>XP_005251910
          Length = 1839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RVLRCL
Sbjct: 530 RVLRCL 535
>XP_005251909
          Length = 1839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RVLRCL
Sbjct: 530 RVLRCL 535
>XP_005251908
          Length = 1839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RVLRCL
Sbjct: 530 RVLRCL 535
>XP_005251907
          Length = 1845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RVLRCL
Sbjct: 536 RVLRCL 541
>NP_001131145
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RVL CLA
Sbjct: 274 RVLECLA 280
>NP_703194
          Length = 690

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RVL CLA
Sbjct: 274 RVLECLA 280
>NP_060090
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RVL CLA
Sbjct: 274 RVLECLA 280
>NP_036350
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RVL CLA
Sbjct: 274 RVLECLA 280
>NP_004507
          Length = 702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RVL CLA
Sbjct: 274 RVLECLA 280
>NP_001265455
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QARVLRC 7
           ++RVLRC
Sbjct: 699 ESRVLRC 705
>NP_057195
          Length = 837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VLRCLA 9
          VLRCLA
Sbjct: 62 VLRCLA 67
>NP_001265454
          Length = 1483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QARVLRC 7
            ++RVLRC
Sbjct: 1229 ESRVLRC 1235
>NP_001265453
          Length = 1483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QARVLRC 7
            ++RVLRC
Sbjct: 1229 ESRVLRC 1235
>NP_055618
          Length = 1483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QARVLRC 7
            ++RVLRC
Sbjct: 1229 ESRVLRC 1235
>XP_005259952
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  RVLRCLA 9
          RVL CLA
Sbjct: 9  RVLECLA 15
>XP_006722805
          Length = 855

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RVL CLA
Sbjct: 274 RVLECLA 280
>XP_006721056
          Length = 718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  VLRCLA 9
          VLRCLA
Sbjct: 62 VLRCLA 67
>NP_001268901
          Length = 222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   QARVLRCL 8
           Q RV+ CL
Sbjct: 203 QTRVIHCL 210
>NP_001268900
          Length = 239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   QARVLRCL 8
           Q RV+ CL
Sbjct: 203 QTRVIHCL 210
>NP_003027
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           QAR+ RCL
Sbjct: 297 QARLGRCL 304
>NP_078891
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QARVLRCLA 9
           Q+R L+C+A
Sbjct: 781 QSRNLKCIA 789
>NP_001265723
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   ARVLRCL 8
           AR+ RCL
Sbjct: 235 ARIYRCL 241
>NP_001171526
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QARVLRCLA 9
           Q+R L+C+A
Sbjct: 781 QSRNLKCIA 789
>NP_001171527
          Length = 812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QARVLRCLA 9
           Q+R L+C+A
Sbjct: 739 QSRNLKCIA 747
>NP_001127948
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>NP_056165
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>NP_005963
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   ARVLRCL 8
           AR+ RCL
Sbjct: 235 ARIYRCL 241
>NP_660358
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           Q RV++CL
Sbjct: 94  QRRVIQCL 101
>NP_001095841
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RV+RCL
Sbjct: 334 RVIRCL 339
>NP_079231
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RVLRCL 8
           RV+RCL
Sbjct: 334 RVIRCL 339
>NP_001017987
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QARVLRC 7
          ++RVLRC
Sbjct: 6  RSRVLRC 12
>NP_005984
          Length = 1192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ARVLRCL 8
           A VLRCL
Sbjct: 274 ATVLRCL 280
>XP_006722353
          Length = 1165

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ARVLRCL 8
           A VLRCL
Sbjct: 274 ATVLRCL 280
>XP_005256453
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ARVLRCL 8
           A VLRCL
Sbjct: 257 ATVLRCL 263
>XP_006722333
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           + RVL+CL
Sbjct: 154 RTRVLKCL 161
>XP_005249600
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ARVLRCLA 9
           A V+RC+A
Sbjct: 162 ASVMRCIA 169
>XP_005249599
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ARVLRCLA 9
           A V+RC+A
Sbjct: 162 ASVMRCIA 169
>XP_005266942
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q RV++CL
Sbjct: 61 QRRVIQCL 68
>XP_005248654
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QARVLRCLA 9
           Q+R L+C+A
Sbjct: 534 QSRNLKCIA 542
>XP_005248653
          Length = 895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QARVLRCLA 9
           Q+R L+C+A
Sbjct: 822 QSRNLKCIA 830
>XP_005244832
          Length = 730

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           QAR+ RCL
Sbjct: 297 QARLGRCL 304
>XP_005270761
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>XP_005270760
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>XP_005270759
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>XP_006710604
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>XP_005270758
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QARVLRCL 8
          Q+RVL CL
Sbjct: 49 QSRVLCCL 56
>NP_005533
          Length = 277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ARVLRCLA 9
           A V+RC+A
Sbjct: 162 ASVMRCIA 169
>NP_001129475
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QARVLRCLA 9
           Q+RV++C A
Sbjct: 274 QSRVVKCSA 282
>NP_598377
          Length = 1207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QARVLRCL 8
            Q+RV++C+
Sbjct: 1108 QSRVIQCM 1115
>NP_057259
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QARVLRC 7
          ++RVLRC
Sbjct: 6  RSRVLRC 12
>NP_001191355
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           + +V+RCL
Sbjct: 350 EVKVMRCL 357
>NP_004950
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           +AR+L CL
Sbjct: 241 RARILGCL 248
>NP_620688
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QARVLRCL 8
            Q+RV++C+
Sbjct: 993  QSRVVQCM 1000
>NP_434701
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           +AR LRC+
Sbjct: 312 EARRLRCM 319
>NP_434700
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           +AR LRC+
Sbjct: 312 EARRLRCM 319
>NP_060857
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RV+ CLA
Sbjct: 266 RVMECLA 272
>NP_001164608
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RV+ CLA
Sbjct: 252 RVMECLA 258
>NP_060282
          Length = 227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QARVLRC 7
           QA++L+C
Sbjct: 187 QAKILQC 193
>NP_078904
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   RVLRCLA 9
           R+L+C+A
Sbjct: 333 RILQCIA 339
>NP_002305
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           + +V+RCL
Sbjct: 384 EVKVMRCL 391
>NP_001182412
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   RVLRCLA 9
           R+L+C+A
Sbjct: 333 RILQCIA 339
>NP_055049
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  QARVLRCL 8
          +AR  RCL
Sbjct: 78 EARAARCL 85
>XP_005254929
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    QARVLRCL 8
            Q+RV++C+
Sbjct: 1020 QSRVVQCM 1027
>XP_005252142
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RV+ CLA
Sbjct: 266 RVMECLA 272
>XP_005252140
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RVLRCLA 9
           RV+ CLA
Sbjct: 266 RVMECLA 272
>XP_005251930
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           +AR+L CL
Sbjct: 241 RARILGCL 248
>XP_005251929
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           +AR+L CL
Sbjct: 154 RARILGCL 161
>XP_005251928
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QARVLRCL 8
           +AR+L CL
Sbjct: 241 RARILGCL 248
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.140    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 569,081
Number of extensions: 623
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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