Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              19     869
XP_005273257                                                           19     869
NP_000032                                                              17    2528
XP_005258924                                                           17    2528
NP_001154976                                                           17    3301
NP_733844                                                              17    3301
NP_003739                                                              17    3301
NP_001193928                                                           16    5631
NP_009105                                                              16    5631
XP_005253886                                                           16    5631
XP_006719269                                                           16    5631
NP_663622                                                              15    9605
XP_006726466                                                           15    9605
XP_005251162                                                           15    9605
XP_005251161                                                           15    9605
XP_005251160                                                           15    9605
XP_005251159                                                           15    9605
XP_006712969                                                           15    9605
XP_006710208                                                           15    9605
NP_001138560                                                           15    9605
>NP_064450
          Length = 1722

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAKIDQAAE 9
            QAKIDQ AE
Sbjct: 1619 QAKIDQEAE 1627
>XP_005273257
          Length = 1726

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAKIDQAAE 9
            QAKIDQ AE
Sbjct: 1623 QAKIDQEAE 1631
>NP_000032
          Length = 317

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QAKIDQAAE 9
          QAK++QA E
Sbjct: 17 QAKVEQAVE 25
>XP_005258924
          Length = 343

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QAKIDQAAE 9
          QAK++QA E
Sbjct: 43 QAKVEQAVE 51
>NP_001154976
          Length = 503

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAKIDQAAE 9
           QA+ID AAE
Sbjct: 97  QAEIDAAAE 105
>NP_733844
          Length = 563

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAKIDQAAE 9
           QA+ID AAE
Sbjct: 157 QAEIDAAAE 165
>NP_003739
          Length = 563

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QAKIDQAAE 9
           QA+ID AAE
Sbjct: 157 QAEIDAAAE 165
>NP_001193928
          Length = 2069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QAKIDQAAE 9
            QAK+DQ A+
Sbjct: 1269 QAKMDQPAK 1277
>NP_009105
          Length = 2027

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QAKIDQAAE 9
            QAK+DQ A+
Sbjct: 1227 QAKMDQPAK 1235
>XP_005253886
          Length = 1545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAKIDQAAE 9
           QAK+DQ A+
Sbjct: 761 QAKMDQPAK 769
>XP_006719269
          Length = 2054

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QAKIDQAAE 9
            QAK+DQ A+
Sbjct: 1269 QAKMDQPAK 1277
>NP_663622
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QAKIDQ 6
           QAK+DQ
Sbjct: 713 QAKVDQ 718
>XP_006726466
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QAKIDQA 7
           QA++DQA
Sbjct: 869 QARLDQA 875
>XP_005251162
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QAKIDQ 6
           QAK+DQ
Sbjct: 608 QAKVDQ 613
>XP_005251161
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QAKIDQ 6
           QAK+DQ
Sbjct: 634 QAKVDQ 639
>XP_005251160
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QAKIDQ 6
           QAK+DQ
Sbjct: 713 QAKVDQ 718
>XP_005251159
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QAKIDQ 6
           QAK+DQ
Sbjct: 713 QAKVDQ 718
>XP_006712969
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QAKIDQA 7
           QA++DQA
Sbjct: 869 QARLDQA 875
>XP_006710208
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QAKIDQA 7
           QA++DQA
Sbjct: 225 QARLDQA 231
>NP_001138560
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QAKIDQ 6
           QAK+DQ
Sbjct: 713 QAKVDQ 718
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.110    0.252 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 277,096
Number of extensions: 183
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package