Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006726410                                                           18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_006710143                                                           18    1482
XP_006710142                                                           18    1482
XP_006710141                                                           18    1482
NP_001124456                                                           16    7355
NP_001124448                                                           16    7355
NP_003485                                                              16    7355
NP_001123927                                                           16    7355
NP_001124454                                                           16    7355
NP_001124452                                                           16    7355
NP_001124459                                                           16    7355
NP_001124455                                                           16    7355
NP_001124457                                                           16    7355
NP_001124450                                                           16    7355
NP_001124451                                                           16    7355
NP_001124449                                                           16    7355
NP_001124458                                                           16    7355
NP_001124453                                                           16    7355
NP_001269287                                                           16    7355
NP_078894                                                              16    7355
NP_001269072                                                           16    7355
NP_001269073                                                           16    7355
NP_001185771                                                           16    7355
XP_005276585                                                           16    7355
XP_005255567                                                           16    7355
XP_005255566                                                           16    7355
XP_370934                                                              16    7355
XP_006718967                                                           16    7355
XP_005271726                                                           16    7355
XP_005264642                                                           16    7355
XP_005264641                                                           16    7355
XP_001716413                                                           16    7355
NP_006422                                                              16    7355
NP_078934                                                              15    9605
NP_068735                                                              15    9605
NP_002522                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1515 QAGLEPLAL 1523
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1559 QAGLEPLAL 1567
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1559 QAGLEPLAL 1567
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1362 QAGLEPLAL 1370
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1515 QAGLEPLAL 1523
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           QAGLE LAL
Sbjct: 566 QAGLEPLAL 574
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1515 QAGLEPLAL 1523
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1624 QAGLEPLAL 1632
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1558 QAGLEPLAL 1566
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1559 QAGLEPLAL 1567
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1562 QAGLEPLAL 1570
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1612 QAGLEPLAL 1620
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1624 QAGLEPLAL 1632
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1625 QAGLEPLAL 1633
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1721 QAGLEPLAL 1729
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1722 QAGLEPLAL 1730
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QAGLEQLAL 9
            QAGLE LAL
Sbjct: 1362 QAGLEPLAL 1370
>XP_006710143
          Length = 562

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           QAGLE LAL
Sbjct: 401 QAGLEPLAL 409
>XP_006710142
          Length = 671

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           QAGLE LAL
Sbjct: 510 QAGLEPLAL 518
>XP_006710141
          Length = 672

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           QAGLE LAL
Sbjct: 511 QAGLEPLAL 519
>NP_001124456
          Length = 2088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 673 EAGLEQVHL 681
>NP_001124448
          Length = 2066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 672 EAGLEQVHL 680
>NP_003485
          Length = 2080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 686 EAGLEQVHL 694
>NP_001123927
          Length = 2081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 687 EAGLEQVHL 695
>NP_001124454
          Length = 2112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 718 EAGLEQVHL 726
>NP_001124452
          Length = 2097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 703 EAGLEQVHL 711
>NP_001124459
          Length = 2119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 704 EAGLEQVHL 712
>NP_001124455
          Length = 2102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 687 EAGLEQVHL 695
>NP_001124457
          Length = 2098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 704 EAGLEQVHL 712
>NP_001124450
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 686 EAGLEQVHL 694
>NP_001124451
          Length = 2111

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 717 EAGLEQVHL 725
>NP_001124449
          Length = 2087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 672 EAGLEQVHL 680
>NP_001124458
          Length = 2067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 673 EAGLEQVHL 681
>NP_001124453
          Length = 2118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 703 EAGLEQVHL 711
>NP_001269287
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAGLEQLAL 9
           QAGL  LAL
Sbjct: 138 QAGLPPLAL 146
>NP_078894
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAGLEQLAL 9
           QAGL  LAL
Sbjct: 138 QAGLPPLAL 146
>NP_001269072
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAGLEQLAL 9
           QAGL  LAL
Sbjct: 138 QAGLPPLAL 146
>NP_001269073
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAGLEQLAL 9
           QAGL  LAL
Sbjct: 138 QAGLPPLAL 146
>NP_001185771
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AGLEQLAL 9
           AG+E+LAL
Sbjct: 271 AGVERLAL 278
>XP_005276585
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QAGLEQL 7
           Q GLEQL
Sbjct: 320 QVGLEQL 326
>XP_005255567
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AGLEQLA 8
           AGLEQL+
Sbjct: 152 AGLEQLS 158
>XP_005255566
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AGLEQLA 8
           AGLEQL+
Sbjct: 153 AGLEQLS 159
>XP_370934
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QAGLEQL 7
           Q GLEQL
Sbjct: 320 QVGLEQL 326
>XP_006718967
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAGLEQLAL 9
           QAGL  LAL
Sbjct: 138 QAGLPPLAL 146
>XP_005271726
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QAGLEQLAL 9
           QAGL  LAL
Sbjct: 138 QAGLPPLAL 146
>XP_005264642
          Length = 2132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 717 EAGLEQVHL 725
>XP_005264641
          Length = 2133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QAGLEQLAL 9
           +AGLEQ+ L
Sbjct: 718 EAGLEQVHL 726
>XP_001716413
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QAGLEQL 7
           Q GLEQL
Sbjct: 320 QVGLEQL 326
>NP_006422
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   AGLEQLAL 9
           AG+E+LAL
Sbjct: 318 AGVERLAL 325
>NP_078934
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 AGLEQL 7
         AGLEQL
Sbjct: 4 AGLEQL 9
>NP_068735
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QAGLEQLAL 9
          + GLEQ+A+
Sbjct: 38 ERGLEQMAV 46
>NP_002522
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QAGLEQLAL 9
          QAGLE+  L
Sbjct: 23 QAGLEEALL 31
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.131    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 492,682
Number of extensions: 610
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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