Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1135
NP_001263689                                                           18    1135
NP_001119584                                                           18    1135
NP_001119586                                                           18    1135
NP_001263625                                                           18    1135
NP_001119590                                                           18    1135
NP_001263690                                                           18    1135
NP_001119585                                                           18    1135
NP_001263624                                                           18    1135
NP_001119588                                                           18    1135
NP_001119587                                                           18    1135
NP_001119589                                                           18    1135
NP_653215                                                              16    5631
NP_001157897                                                           16    5631
NP_001129979                                                           16    5631
XP_005276700                                                           16    5631
XP_001130308                                                           16    5631
XP_003403895                                                           16    5631
NP_001157891                                                           16    5631
NP_004971                                                              16    7355
NP_751948                                                              16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_596870                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
XP_006710693                                                           16    7355
XP_006710692                                                           16    7355
XP_005270908                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_005378                                                              15    9605
NP_624357                                                              15    9605
NP_005135                                                              15    9605
NP_624358                                                              15    9605
NP_057404                                                              15    9605
NP_060881                                                              15    9605
NP_037411                                                              15    9605
NP_001120864                                                           15    9605
XP_005274286                                                           15    9605
XP_005274285                                                           15    9605
XP_005274284                                                           15    9605
XP_005274283                                                           15    9605
XP_005274282                                                           15    9605
XP_005274281                                                           15    9605
XP_005274280                                                           15    9605
XP_005274279                                                           15    9605
XP_006718305                                                           15    9605
XP_006718304                                                           15    9605
XP_006718303                                                           15    9605
XP_005253007                                                           15    9605
XP_006716430                                                           15    9605
XP_005273626                                                           15    9605
>NP_000537
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 153 PGTRVRAMA 161
>NP_001263689
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 114 PGTRVRAMA 122
>NP_001119584
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 153 PGTRVRAMA 161
>NP_001119586
          Length = 341

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 153 PGTRVRAMA 161
>NP_001263625
          Length = 302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 114 PGTRVRAMA 122
>NP_001119590
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 114 PGTRVRAMA 122
>NP_001263690
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 114 PGTRVRAMA 122
>NP_001119585
          Length = 346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 153 PGTRVRAMA 161
>NP_001263624
          Length = 307

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVTRVRAMA 9
           P TRVRAMA
Sbjct: 114 PGTRVRAMA 122
>NP_001119588
          Length = 209

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PVTRVRAMA 9
          P TRVRAMA
Sbjct: 21 PGTRVRAMA 29
>NP_001119587
          Length = 261

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PVTRVRAMA 9
          P TRVRAMA
Sbjct: 21 PGTRVRAMA 29
>NP_001119589
          Length = 214

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PVTRVRAMA 9
          P TRVRAMA
Sbjct: 21 PGTRVRAMA 29
>NP_653215
          Length = 208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>NP_001157897
          Length = 208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>NP_001129979
          Length = 208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>XP_005276700
          Length = 204

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>XP_001130308
          Length = 204

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>XP_003403895
          Length = 204

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>NP_001157891
          Length = 208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PVTRVRA 7
          PVTR+R+
Sbjct: 60 PVTRIRS 66
>NP_004971
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           P TR+R+M
Sbjct: 563 PATRLRSM 570
>NP_751948
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           P TR+R+M
Sbjct: 544 PATRLRSM 551
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1352 PVSRIRSLS 1360
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1352 PVSRIRSLS 1360
>NP_596870
          Length = 5604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1398 PVSRIRSLS 1406
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1398 PVSRIRSLS 1406
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1398 PVSRIRSLS 1406
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1399 PVSRIRSLS 1407
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1399 PVSRIRSLS 1407
>XP_006710693
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           P TR+R+M
Sbjct: 544 PATRLRSM 551
>XP_006710692
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           P TR+R+M
Sbjct: 563 PATRLRSM 570
>XP_005270908
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           P TR+R+M
Sbjct: 563 PATRLRSM 570
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1398 PVSRIRSLS 1406
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    PVTRVRAMA 9
            PV+R+R+++
Sbjct: 1352 PVSRIRSLS 1360
>NP_005378
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 556 PATRVRPKA 564
>NP_624357
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 539 PATRVRPKA 547
>NP_005135
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           PV R+RA+
Sbjct: 404 PVARLRAL 411
>NP_624358
          Length = 1726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 539 PATRVRPKA 547
>NP_057404
          Length = 1800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 539 PATRVRPKA 547
>NP_060881
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           PV R+RA+
Sbjct: 404 PVARLRAL 411
>NP_037411
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 895 PVTNIRA 901
>NP_001120864
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 930 PVTNIRA 936
>XP_005274286
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 817 PVTNIRA 823
>XP_005274285
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 880 PVTNIRA 886
>XP_005274284
          Length = 1120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 904 PVTNIRA 910
>XP_005274283
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 903 PVTNIRA 909
>XP_005274282
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 904 PVTNIRA 910
>XP_005274281
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 930 PVTNIRA 936
>XP_005274280
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 931 PVTNIRA 937
>XP_005274279
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVTRVRA 7
           PVT +RA
Sbjct: 931 PVTNIRA 937
>XP_006718305
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 556 PATRVRPKA 564
>XP_006718304
          Length = 1753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 492 PATRVRPKA 500
>XP_006718303
          Length = 1792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 531 PATRVRPKA 539
>XP_005253007
          Length = 1817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PVTRVRAMA 9
           P TRVR  A
Sbjct: 556 PATRVRPKA 564
>XP_006716430
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           PV R+RA+
Sbjct: 404 PVARLRAL 411
>XP_005273626
          Length = 1190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVTRVRAM 8
           PV R+RA+
Sbjct: 404 PVARLRAL 411
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.129    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 306,263
Number of extensions: 344
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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