Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_116207                                                              16    5631
NP_057347                                                              16    7355
NP_004090                                                              16    7355
XP_005259630                                                           16    7355
XP_005268734                                                           16    7355
XP_005252119                                                           16    7355
NP_689653                                                              16    7355
NP_001129670                                                           16    7355
NP_001129669                                                           16    7355
NP_004623                                                              15    9605
NP_001186779                                                           15    9605
NP_001186778                                                           15    9605
NP_006552                                                              15    9605
NP_001077060                                                           15    9605
NP_001020248                                                           15    9605
NP_001020247                                                           15    9605
NP_387506                                                              15    9605
NP_057332                                                              15    9605
NP_006551                                                              15    9605
NP_001166110                                                           15    9605
NP_941989                                                              15    9605
NP_001138923                                                           15    9605
NP_001166111                                                           15    9605
NP_001020767                                                           15    9605
XP_005266307                                                           15    9605
XP_005266306                                                           15    9605
XP_005266305                                                           15    9605
XP_005266304                                                           15    9605
XP_006718194                                                           15    9605
XP_006718193                                                           15    9605
XP_006718192                                                           15    9605
XP_006718191                                                           15    9605
XP_006718190                                                           15    9605
XP_005252813                                                           15    9605
XP_005252812                                                           15    9605
XP_006718189                                                           15    9605
XP_006718188                                                           15    9605
XP_006718187                                                           15    9605
XP_005252811                                                           15    9605
XP_006718186                                                           15    9605
XP_006718185                                                           15    9605
XP_005252414                                                           15    9605
XP_005252415                                                           15    9605
XP_006717438                                                           15    9605
XP_006717437                                                           15    9605
XP_006717436                                                           15    9605
XP_006717435                                                           15    9605
XP_006717434                                                           15    9605
XP_005252411                                                           15    9605
XP_006717433                                                           15    9605
XP_006717432                                                           15    9605
XP_006717431                                                           15    9605
XP_006717430                                                           15    9605
XP_005252408                                                           15    9605
XP_005252406                                                           15    9605
XP_005252405                                                           15    9605
XP_006717429                                                           15    9605
XP_006717428                                                           15    9605
XP_005245537                                                           15    9605
XP_006711590                                                           15    9605
>NP_116207
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PVQSQRA 7
          PVQ QRA
Sbjct: 11 PVQEQRA 17
>NP_057347
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVQSQRAVQ 9
           P+QS+R +Q
Sbjct: 302 PLQSERRLQ 310
>NP_004090
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PVQSQRAV 8
           PVQ QRA+
Sbjct: 200 PVQLQRAM 207
>XP_005259630
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVQSQRAVQ 9
           P+QS+R +Q
Sbjct: 302 PLQSERRLQ 310
>XP_005268734
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QSQRAVQ 9
           QSQ+AVQ
Sbjct: 244 QSQKAVQ 250
>XP_005252119
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVQSQRAVQ 9
           P ++QRAVQ
Sbjct: 93  PGKNQRAVQ 101
>NP_689653
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QSQRAVQ 9
           QSQ+AVQ
Sbjct: 244 QSQKAVQ 250
>NP_001129670
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVQSQRAVQ 9
           P+QS+R +Q
Sbjct: 302 PLQSERRLQ 310
>NP_001129669
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVQSQRAVQ 9
           P+QS+R +Q
Sbjct: 213 PLQSERRLQ 221
>NP_004623
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PVQSQRAV 8
          PV+S RA+
Sbjct: 41 PVESPRAI 48
>NP_001186779
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PVQSQRAV 8
          PV+S RA+
Sbjct: 41 PVESPRAI 48
>NP_001186778
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PVQSQRAV 8
          PV+S RA+
Sbjct: 41 PVESPRAI 48
>NP_006552
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 487 PVSAQAAIQ 495
>NP_001077060
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 454 PVSAQAAIQ 462
>NP_001020248
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 474 PVSAQAAIQ 482
>NP_001020247
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 456 PVSAQAAIQ 464
>NP_387506
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PVQSQRAV 8
          PV+S RA+
Sbjct: 41 PVESPRAI 48
>NP_057332
          Length = 1901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VQSQRAV 8
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>NP_006551
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 448 PVSAQAAIQ 456
>NP_001166110
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 478 PVSAQAAIQ 486
>NP_941989
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 449 PVSAQAAIQ 457
>NP_001138923
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PVQSQRAVQ 9
           P++++RA Q
Sbjct: 737 PIKAERAAQ 745
>NP_001166111
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 451 PVSAQAAIQ 459
>NP_001020767
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 452 PVSAQAAIQ 460
>XP_005266307
          Length = 1796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VQSQRAV 8
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>XP_005266306
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VQSQRAV 8
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>XP_005266305
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VQSQRAV 8
            VQSQR+V
Sbjct: 1190 VQSQRSV 1196
>XP_005266304
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VQSQRAV 8
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241
>XP_006718194
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 453 PVSAQAAIQ 461
>XP_006718193
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 453 PVSAQAAIQ 461
>XP_006718192
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 453 PVSAQAAIQ 461
>XP_006718191
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 453 PVSAQAAIQ 461
>XP_006718190
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 479 PVSAQAAIQ 487
>XP_005252813
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 480 PVSAQAAIQ 488
>XP_005252812
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 485 PVSAQAAIQ 493
>XP_006718189
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 485 PVSAQAAIQ 493
>XP_006718188
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 488 PVSAQAAIQ 496
>XP_006718187
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 488 PVSAQAAIQ 496
>XP_005252811
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 489 PVSAQAAIQ 497
>XP_006718186
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 489 PVSAQAAIQ 497
>XP_006718185
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 489 PVSAQAAIQ 497
>XP_005252414
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 246 PVSAQAAIQ 254
>XP_005252415
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 246 PVSAQAAIQ 254
>XP_006717438
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 256 PVSAQAAIQ 264
>XP_006717437
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 256 PVSAQAAIQ 264
>XP_006717436
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 369 PVSAQAAIQ 377
>XP_006717435
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 373 PVSAQAAIQ 381
>XP_006717434
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 373 PVSAQAAIQ 381
>XP_005252411
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 480 PVSAQAAIQ 488
>XP_006717433
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 484 PVSAQAAIQ 492
>XP_006717432
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 491 PVSAQAAIQ 499
>XP_006717431
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 496 PVSAQAAIQ 504
>XP_006717430
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 503 PVSAQAAIQ 511
>XP_005252408
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 505 PVSAQAAIQ 513
>XP_005252406
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 509 PVSAQAAIQ 517
>XP_005252405
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 511 PVSAQAAIQ 519
>XP_006717429
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 515 PVSAQAAIQ 523
>XP_006717428
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVQSQRAVQ 9
           PV +Q A+Q
Sbjct: 515 PVSAQAAIQ 523
>XP_005245537
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PVQSQRAV 8
          PV+S RA+
Sbjct: 41 PVESPRAI 48
>XP_006711590
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PVQSQRAV 8
          PV+S RA+
Sbjct: 41 PVESPRAI 48
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.116    0.296 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 325,902
Number of extensions: 389
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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