Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     299
NP_671714                                                              20     299
XP_006715890                                                           20     299
XP_005250160                                                           20     299
XP_005250159                                                           20     299
NP_065769                                                              18    1935
XP_006721134                                                           18    1935
XP_005255507                                                           18    1935
NP_002678                                                              17    2528
NP_005106                                                              17    3301
NP_059447                                                              17    3301
NP_000532                                                              17    4312
NP_064647                                                              17    4312
NP_001244257                                                           17    4312
NP_004304                                                              17    4312
NP_001244259                                                           17    4312
NP_001244258                                                           17    4312
NP_004032                                                              17    4312
NP_001135778                                                           17    4312
XP_005274055                                                           17    4312
XP_005274054                                                           17    4312
XP_006718618                                                           17    4312
XP_006718617                                                           17    4312
XP_006718616                                                           17    4312
XP_006718615                                                           17    4312
XP_006714920                                                           17    4312
XP_006714919                                                           17    4312
XP_005246156                                                           17    4312
NP_004303                                                              16    5631
NP_653219                                                              16    5631
XP_006711216                                                           16    5631
XP_005244942                                                           16    5631
XP_005244941                                                           16    5631
XP_005244940                                                           16    5631
XP_006711215                                                           16    5631
XP_005244939                                                           16    5631
XP_006711214                                                           16    5631
XP_005244938                                                           16    5631
XP_005244937                                                           16    5631
NP_004332                                                              16    7355
NP_004165                                                              16    7355
NP_001271280                                                           16    7355
NP_001193602                                                           16    7355
NP_061760                                                              16    7355
NP_001254505                                                           16    7355
NP_694942                                                              16    7355
XP_006720115                                                           16    7355
XP_005267414                                                           16    7355
XP_005267413                                                           16    7355
XP_005264615                                                           16    7355
XP_006712164                                                           16    7355
XP_005264614                                                           16    7355
XP_005264613                                                           16    7355
XP_005264612                                                           16    7355
NP_861535                                                              16    7355
NP_112533                                                              15    9605
NP_002128                                                              15    9605
NP_705838                                                              15    9605
NP_003782                                                              15    9605
NP_001258468                                                           15    9605
XP_006723719                                                           15    9605
XP_006723718                                                           15    9605
XP_006723716                                                           15    9605
XP_006723715                                                           15    9605
XP_006723714                                                           15    9605
XP_006723713                                                           15    9605
XP_006723712                                                           15    9605
XP_006723711                                                           15    9605
XP_006723710                                                           15    9605
XP_006723709                                                           15    9605
XP_006715777                                                           15    9605
XP_005249786                                                           15    9605
>NP_005742
          Length = 3907

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PVDSVVLTE 9
            PVDSVV+TE
Sbjct: 1385 PVDSVVITE 1393
>NP_671714
          Length = 3899

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PVDSVVLTE 9
            PVDSVV+TE
Sbjct: 1385 PVDSVVITE 1393
>XP_006715890
          Length = 3860

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PVDSVVLTE 9
            PVDSVV+TE
Sbjct: 1385 PVDSVVITE 1393
>XP_005250160
          Length = 3939

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PVDSVVLTE 9
            PVDSVV+TE
Sbjct: 1385 PVDSVVITE 1393
>XP_005250159
          Length = 3952

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PVDSVVLTE 9
            PVDSVV+TE
Sbjct: 1385 PVDSVVITE 1393
>NP_065769
          Length = 1352

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           P D +VLTE
Sbjct: 360 PTDQIVLTE 368
>XP_006721134
          Length = 1089

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           P D +VLTE
Sbjct: 97  PTDQIVLTE 105
>XP_005255507
          Length = 1089

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           P D +VLTE
Sbjct: 97  PTDQIVLTE 105
>NP_002678
          Length = 717

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+SV LTE
Sbjct: 531 PVESVKLTE 539
>NP_005106
          Length = 893

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+V+LTE
Sbjct: 216 VDAVILTE 223
>NP_059447
          Length = 893

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+V+LTE
Sbjct: 216 VDAVILTE 223
>NP_000532
          Length = 405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 44 PVDGVVLVD 52
>NP_064647
          Length = 410

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 36 PVDGVVLVD 44
>NP_001244257
          Length = 430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 37 PVDGVVLVD 45
>NP_004304
          Length = 409

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 37 PVDGVVLVD 45
>NP_001244259
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 37 PVDGVVLVD 45
>NP_001244258
          Length = 330

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 37 PVDGVVLVD 45
>NP_004032
          Length = 418

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 36 PVDGVVLVD 44
>NP_001135778
          Length = 277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PVDSVVLTE 9
          P+DSV+ TE
Sbjct: 20 PLDSVIGTE 28
>XP_005274055
          Length = 414

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 40 PVDGVVLVD 48
>XP_005274054
          Length = 422

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 40 PVDGVVLVD 48
>XP_006718618
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 31 PVDGVVLVD 39
>XP_006718617
          Length = 439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 40 PVDGVVLVD 48
>XP_006718616
          Length = 443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 36 PVDGVVLVD 44
>XP_006718615
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 40 PVDGVVLVD 48
>XP_006714920
          Length = 281

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PVDSVVLTE 9
          P+DSV+ TE
Sbjct: 20 PLDSVIGTE 28
>XP_006714919
          Length = 353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PVDSVVLTE 9
          P+DSV+ TE
Sbjct: 20 PLDSVIGTE 28
>XP_005246156
          Length = 405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          PVD VVL +
Sbjct: 44 PVDGVVLVD 52
>NP_004303
          Length = 388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PVDSVVLTE 9
          P+D VVL +
Sbjct: 32 PIDGVVLVD 40
>NP_653219
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 411 VDAVVVTE 418
>XP_006711216
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 355 VDAVVVTE 362
>XP_005244942
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 355 VDAVVVTE 362
>XP_005244941
          Length = 410

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 373 VDAVVVTE 380
>XP_005244940
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 389 VDAVVVTE 396
>XP_006711215
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 411 VDAVVVTE 418
>XP_005244939
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 411 VDAVVVTE 418
>XP_006711214
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 427 VDAVVVTE 434
>XP_005244938
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 427 VDAVVVTE 434
>XP_005244937
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDSVVLTE 9
           VD+VV+TE
Sbjct: 427 VDAVVVTE 434
>NP_004332
          Length = 2225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+++ LTE
Sbjct: 505 PVETIELTE 513
>NP_004165
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVDSVVLT 8
           P+D VVL+
Sbjct: 403 PIDQVVLS 410
>NP_001271280
          Length = 825

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PVDSVVLT 8
           P+D VVL+
Sbjct: 403 PIDQVVLS 410
>NP_001193602
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVDSVVL 7
           PVD++VL
Sbjct: 236 PVDAIVL 242
>NP_061760
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PVDSVVLT 8
           PV+SV++T
Sbjct: 256 PVNSVIVT 263
>NP_001254505
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PVDSVVLTE 9
           P D V+L E
Sbjct: 320 PADEVILVE 328
>NP_694942
          Length = 1123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PVDSVVLTE 9
           P D V+L E
Sbjct: 320 PADEVILVE 328
>XP_006720115
          Length = 189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVDSVVL 7
           PVD++VL
Sbjct: 159 PVDAIVL 165
>XP_005267414
          Length = 235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVDSVVL 7
           PVD++VL
Sbjct: 159 PVDAIVL 165
>XP_005267413
          Length = 255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVDSVVL 7
           PVD++VL
Sbjct: 129 PVDAIVL 135
>XP_005264615
          Length = 2162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+++ LTE
Sbjct: 505 PVETIELTE 513
>XP_006712164
          Length = 2179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+++ LTE
Sbjct: 505 PVETIELTE 513
>XP_005264614
          Length = 2191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+++ LTE
Sbjct: 505 PVETIELTE 513
>XP_005264613
          Length = 2208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+++ LTE
Sbjct: 505 PVETIELTE 513
>XP_005264612
          Length = 2242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PVDSVVLTE 9
           PV+++ LTE
Sbjct: 505 PVETIELTE 513
>NP_861535
          Length = 285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVDSVVL 7
           PVD++VL
Sbjct: 159 PVDAIVL 165
>NP_112533
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVDSVVL 7
           PVD +VL
Sbjct: 165 PVDKIVL 171
>NP_002128
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVDSVVL 7
           PVD +VL
Sbjct: 153 PVDKIVL 159
>NP_705838
          Length = 4069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    PVDSVVLTE 9
            PVD  VLT+
Sbjct: 1382 PVDRPVLTK 1390
>NP_003782
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           P D VV+T+
Sbjct: 797 PEDGVVITQ 805
>NP_001258468
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723719
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723718
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723716
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723715
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723714
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723713
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723712
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 175 PVEKVRLTE 183
>XP_006723711
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723710
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006723709
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVDSVVLTE 9
           PV+ V LTE
Sbjct: 260 PVEKVRLTE 268
>XP_006715777
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVDSVVL 7
           PVD +VL
Sbjct: 165 PVDKIVL 171
>XP_005249786
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PVDSVVL 7
           PVD +VL
Sbjct: 165 PVDKIVL 171
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.130    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 442,144
Number of extensions: 718
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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