Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           18    1135
NP_004439                                                              18    1135
NP_001276865                                                           18    1135
NP_001005862                                                           18    1135
XP_005257197                                                           18    1135
XP_006721828                                                           18    1135
NP_001185761                                                           17    4312
NP_001185763                                                           17    4312
NP_055459                                                              17    4312
XP_006726410                                                           17    4312
XP_006711719                                                           17    4312
XP_006711718                                                           17    4312
XP_006711717                                                           17    4312
XP_006711716                                                           17    4312
XP_006711715                                                           17    4312
XP_006711714                                                           17    4312
XP_006711713                                                           17    4312
XP_006711712                                                           17    4312
XP_006711711                                                           17    4312
XP_006711710                                                           17    4312
XP_006711709                                                           17    4312
XP_005277503                                                           17    4312
XP_005273038                                                           17    4312
XP_006711708                                                           17    4312
XP_005277500                                                           17    4312
XP_006711707                                                           17    4312
XP_005277499                                                           17    4312
XP_006711706                                                           17    4312
XP_006711705                                                           17    4312
XP_006711164                                                           17    4312
XP_006710143                                                           17    4312
XP_006710142                                                           17    4312
XP_006710141                                                           17    4312
NP_001036064                                                           16    5631
NP_005226                                                              16    5631
XP_005246434                                                           16    5631
XP_005246433                                                           16    5631
XP_005246432                                                           16    5631
XP_006712427                                                           16    5631
NP_689862                                                              16    7355
NP_001245308                                                           16    7355
NP_003606                                                              16    7355
NP_001245309                                                           16    7355
NP_064543                                                              16    7355
XP_005255891                                                           16    7355
XP_005265658                                                           16    7355
XP_005265657                                                           16    7355
XP_005265656                                                           16    7355
XP_005265655                                                           16    7355
XP_006713484                                                           16    7355
NP_001259004                                                           15    9605
NP_005144                                                              15    9605
NP_001265393                                                           15    9605
NP_036192                                                              15    9605
NP_005681                                                              15    9605
NP_036193                                                              15    9605
NP_001265392                                                           15    9605
NP_001265394                                                           15    9605
NP_543013                                                              15    9605
NP_001787                                                              15    9605
XP_006721395                                                           15    9605
XP_006721394                                                           15    9605
XP_006721393                                                           15    9605
XP_005255817                                                           15    9605
XP_005255816                                                           15    9605
XP_005253340                                                           15    9605
XP_005253339                                                           15    9605
>NP_001276866
          Length = 1055

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV RE
Sbjct: 749 PVAIKVLRE 757
>NP_004439
          Length = 1255

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV RE
Sbjct: 749 PVAIKVLRE 757
>NP_001276865
          Length = 1240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV RE
Sbjct: 734 PVAIKVLRE 742
>NP_001005862
          Length = 1225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV RE
Sbjct: 719 PVAIKVLRE 727
>XP_005257197
          Length = 1225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV RE
Sbjct: 719 PVAIKVLRE 727
>XP_006721828
          Length = 1336

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV RE
Sbjct: 830 PVAIKVLRE 838
>NP_001185761
          Length = 2240

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1520 PLALRLSRE 1528
>NP_001185763
          Length = 2362

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1564 PLALRLSRE 1572
>NP_055459
          Length = 2346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1564 PLALRLSRE 1572
>XP_006726410
          Length = 2087

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1367 PLALRLSRE 1375
>XP_006711719
          Length = 2302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1520 PLALRLSRE 1528
>XP_006711718
          Length = 1436

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   PVAIKVSRE 9
           P+A+++SRE
Sbjct: 571 PLALRLSRE 579
>XP_006711717
          Length = 2385

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1520 PLALRLSRE 1528
>XP_006711716
          Length = 2411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1629 PLALRLSRE 1637
>XP_006711715
          Length = 2428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1563 PLALRLSRE 1571
>XP_006711714
          Length = 2429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1564 PLALRLSRE 1572
>XP_006711713
          Length = 2432

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1567 PLALRLSRE 1575
>XP_006711712
          Length = 2473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_006711711
          Length = 2482

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1617 PLALRLSRE 1625
>XP_006711710
          Length = 2494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1629 PLALRLSRE 1637
>XP_006711709
          Length = 2495

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1630 PLALRLSRE 1638
>XP_005277503
          Length = 2498

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_005273038
          Length = 2509

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_006711708
          Length = 2512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_005277500
          Length = 2525

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_006711707
          Length = 2553

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_005277499
          Length = 2561

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_006711706
          Length = 2591

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1726 PLALRLSRE 1734
>XP_006711705
          Length = 2592

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1727 PLALRLSRE 1735
>XP_006711164
          Length = 2087

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    PVAIKVSRE 9
            P+A+++SRE
Sbjct: 1367 PLALRLSRE 1375
>XP_006710143
          Length = 562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   PVAIKVSRE 9
           P+A+++SRE
Sbjct: 406 PLALRLSRE 414
>XP_006710142
          Length = 671

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   PVAIKVSRE 9
           P+A+++SRE
Sbjct: 515 PLALRLSRE 523
>XP_006710141
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   PVAIKVSRE 9
           P+A+++SRE
Sbjct: 516 PLALRLSRE 524
>NP_001036064
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVAIKVSRE 9
           PVAIK+  E
Sbjct: 747 PVAIKILNE 755
>NP_005226
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVAIKVSRE 9
           PVAIK+  E
Sbjct: 747 PVAIKILNE 755
>XP_005246434
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVAIKVSRE 9
           PVAIK+  E
Sbjct: 737 PVAIKILNE 745
>XP_005246433
          Length = 1298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVAIKVSRE 9
           PVAIK+  E
Sbjct: 737 PVAIKILNE 745
>XP_005246432
          Length = 1307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVAIKVSRE 9
           PVAIK+  E
Sbjct: 762 PVAIKILNE 770
>XP_006712427
          Length = 1323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PVAIKVSRE 9
           PVAIK+  E
Sbjct: 762 PVAIKILNE 770
>NP_689862
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV ++
Sbjct: 226 PVAIKVFKK 234
>NP_001245308
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1109 PVSVKISFE 1117
>NP_003606
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1192 PVSVKISFE 1200
>NP_001245309
          Length = 1090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1068 PVSVKISFE 1076
>NP_064543
          Length = 235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PVAIKVSRE 9
          P  +KVS+E
Sbjct: 61 PAEVKVSKE 69
>XP_005255891
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PVAIKVSRE 9
           PVAIKV ++
Sbjct: 226 PVAIKVFKK 234
>XP_005265658
          Length = 1095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1073 PVSVKISFE 1081
>XP_005265657
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1091 PVSVKISFE 1099
>XP_005265656
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1096 PVSVKISFE 1104
>XP_005265655
          Length = 1126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1104 PVSVKISFE 1112
>XP_006713484
          Length = 1255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PVAIKVSRE 9
            PV++K+S E
Sbjct: 1233 PVSVKISFE 1241
>NP_001259004
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVAIKVS 7
           PVAIK++
Sbjct: 395 PVAIKIA 401
>NP_005144
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVAIKVS 7
           PVAIK++
Sbjct: 391 PVAIKIA 397
>NP_001265393
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 209 ALKISRE 215
>NP_036192
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 196 ALKISRE 202
>NP_005681
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 196 ALKISRE 202
>NP_036193
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 196 ALKISRE 202
>NP_001265392
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 196 ALKISRE 202
>NP_001265394
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 209 ALKISRE 215
>NP_543013
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PVAIKV 6
           PVAIKV
Sbjct: 254 PVAIKV 259
>NP_001787
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PVAIKV 6
           PVAIKV
Sbjct: 481 PVAIKV 486
>XP_006721395
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVAIKVS 7
           PVAIK++
Sbjct: 195 PVAIKIA 201
>XP_006721394
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVAIKVS 7
           PVAIK++
Sbjct: 396 PVAIKIA 402
>XP_006721393
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PVAIKVS 7
           PVAIK++
Sbjct: 396 PVAIKIA 402
>XP_005255817
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PVAIKV 6
           PVAIKV
Sbjct: 481 PVAIKV 486
>XP_005255816
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PVAIKV 6
           PVAIKV
Sbjct: 481 PVAIKV 486
>XP_005253340
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AIKVSRE 9
          A+K+SRE
Sbjct: 47 ALKISRE 53
>XP_005253339
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AIKVSRE 9
           A+K+SRE
Sbjct: 209 ALKISRE 215
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 366,597
Number of extensions: 713
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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