Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_073713                                                              20     509
NP_001007526                                                           17    2528
NP_542452                                                              17    4312
XP_006724409                                                           17    4312
XP_005261851                                                           17    4312
XP_005261850                                                           17    4312
NP_001138678                                                           17    4312
NP_055068                                                              16    5631
NP_001156750                                                           16    5631
NP_000912                                                              16    5631
NP_001156751                                                           16    5631
NP_116126                                                              16    5631
NP_001190991                                                           16    5631
NP_036203                                                              16    5631
XP_006724788                                                           16    5631
XP_006719149                                                           16    5631
NP_000238                                                              16    7355
NP_001170990                                                           16    7355
NP_056083                                                              16    7355
NP_892121                                                              16    7355
NP_056311                                                              16    7355
XP_005247302                                                           16    7355
NP_006574                                                              16    7355
NP_036520                                                              15    9605
NP_001157413                                                           15    9605
NP_001164223                                                           15    9605
NP_001073990                                                           15    9605
NP_001265281                                                           15    9605
NP_001269385                                                           15    9605
NP_848654                                                              15    9605
NP_775105                                                              15    9605
NP_001036148                                                           15    9605
NP_116182                                                              15    9605
NP_001129965                                                           15    9605
NP_001274738                                                           15    9605
NP_001274737                                                           15    9605
NP_078888                                                              15    9605
XP_006722146                                                           15    9605
XP_005266479                                                           15    9605
XP_005251533                                                           15    9605
XP_006716840                                                           15    9605
XP_006715506                                                           15    9605
XP_006715505                                                           15    9605
XP_006715504                                                           15    9605
XP_006715503                                                           15    9605
XP_006715502                                                           15    9605
XP_005271342                                                           15    9605
NP_068750                                                              15    9605
NP_002188                                                              15    9605
>NP_073713
          Length = 985

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PTYLLQAGV 9
           PTY LQAGV
Sbjct: 453 PTYPLQAGV 461
>NP_001007526
          Length = 1432

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PTYLLQA 7
           PTY+LQA
Sbjct: 117 PTYVLQA 123
>NP_542452
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PTYLLQA 7
           PT+LLQA
Sbjct: 280 PTWLLQA 286
>XP_006724409
          Length = 1806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TYLLQAG 8
          TY LQAG
Sbjct: 31 TYFLQAG 37
>XP_005261851
          Length = 1806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TYLLQAG 8
          TY LQAG
Sbjct: 31 TYFLQAG 37
>XP_005261850
          Length = 1806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TYLLQAG 8
          TY LQAG
Sbjct: 31 TYFLQAG 37
>NP_001138678
          Length = 1806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TYLLQAG 8
          TY LQAG
Sbjct: 31 TYFLQAG 37
>NP_055068
          Length = 2725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           T+LL AGV
Sbjct: 671 TFLLDAGV 678
>NP_001156750
          Length = 2732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           T+LL AGV
Sbjct: 671 TFLLDAGV 678
>NP_000912
          Length = 1141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AGV
Sbjct: 149 YLLRAGV 155
>NP_001156751
          Length = 2731

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           T+LL AGV
Sbjct: 670 TFLLDAGV 677
>NP_116126
          Length = 620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PTYLLQAG 8
           P Y+L+AG
Sbjct: 519 PKYILRAG 526
>NP_001190991
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TYLLQAG 8
          TY+L+AG
Sbjct: 68 TYILEAG 74
>NP_036203
          Length = 195

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TYLLQAG 8
          TY+L+AG
Sbjct: 68 TYILEAG 74
>XP_006724788
          Length = 2570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           T+LL AGV
Sbjct: 517 TFLLDAGV 524
>XP_006719149
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AGV
Sbjct: 149 YLLRAGV 155
>NP_000238
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PTYLLQAGV 9
          P +LL AG+
Sbjct: 5  PVFLLLAGI 13
>NP_001170990
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PTYLLQAGV 9
          P +LL AG+
Sbjct: 5  PVFLLLAGI 13
>NP_056083
          Length = 2243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TYLLQAGV 9
            T+L QAG+
Sbjct: 1536 THLFQAGI 1543
>NP_892121
          Length = 1147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           T LLQAGV
Sbjct: 475 TGLLQAGV 482
>NP_056311
          Length = 1812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           T LLQAGV
Sbjct: 475 TGLLQAGV 482
>XP_005247302
          Length = 2248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TYLLQAGV 9
            T+L QAG+
Sbjct: 1541 THLFQAGI 1548
>NP_006574
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TYLLQAGV 9
          TYL+ AG+
Sbjct: 30 TYLIMAGM 37
>NP_036520
          Length = 172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PTYLLQAG 8
          P Y L+AG
Sbjct: 16 PPYCLEAG 23
>NP_001157413
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   YLLQAG 8
           YL+QAG
Sbjct: 942 YLIQAG 947
>NP_001164223
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PTYLLQAG 8
           PT LLQ G
Sbjct: 369 PTLLLQYG 376
>NP_001073990
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TYLLQAGV 9
           TYL+ AG+
Sbjct: 276 TYLVGAGI 283
>NP_001265281
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TYLLQAG 8
           TYL+Q G
Sbjct: 318 TYLVQTG 324
>NP_001269385
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PTYLLQAGV 9
           P Y+ QAG+
Sbjct: 131 PHYVAQAGL 139
>NP_848654
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   YLLQAG 8
           YL+QAG
Sbjct: 497 YLIQAG 502
>NP_775105
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>NP_001036148
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>NP_116182
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YLLQAGV 9
           YLL AGV
Sbjct: 242 YLLAAGV 248
>NP_001129965
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YLLQAGV 9
           YLL AGV
Sbjct: 255 YLLAAGV 261
>NP_001274738
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YLLQAGV 9
           YLL AGV
Sbjct: 203 YLLAAGV 209
>NP_001274737
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  YLLQAGV 9
          YLL AGV
Sbjct: 86 YLLAAGV 92
>NP_078888
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PTYLLQAG 8
          P YL +AG
Sbjct: 87 PKYLYEAG 94
>XP_006722146
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PTYLLQAG 8
          P YL +AG
Sbjct: 87 PKYLYEAG 94
>XP_005266479
          Length = 114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1 PTYLLQ 6
         P+YLLQ
Sbjct: 3 PSYLLQ 8
>XP_005251533
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TYLLQAG 8
           TYL+Q G
Sbjct: 318 TYLVQTG 324
>XP_006716840
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TYLLQAG 8
           TYL+Q G
Sbjct: 326 TYLVQTG 332
>XP_006715506
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>XP_006715505
          Length = 1673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>XP_006715504
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>XP_006715503
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>XP_006715502
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   YLLQAGV 9
           YLL+AG+
Sbjct: 215 YLLEAGL 221
>XP_005271342
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YLLQAGV 9
           YLL AGV
Sbjct: 240 YLLAAGV 246
>NP_068750
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PTYLLQAG 8
          P YL +AG
Sbjct: 88 PQYLAEAG 95
>NP_002188
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TYLLQAG 8
           TYL+Q G
Sbjct: 318 TYLVQTG 324
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.141    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 523,817
Number of extensions: 1109
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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