Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           22     134
NP_001257437                                                           22     134
NP_006281                                                              22     134
XP_006715618                                                           22     134
XP_005267176                                                           22     134
NP_001185744                                                           18    1482
XP_005275558                                                           18    1482
XP_005275391                                                           18    1482
XP_005275259                                                           18    1482
XP_005274965                                                           18    1482
XP_005272815                                                           18    1482
XP_005274885                                                           18    1482
XP_005248836                                                           18    1482
NP_054865                                                              18    1935
NP_115852                                                              18    1935
NP_115853                                                              18    1935
XP_005250619                                                           18    1935
NP_001087199                                                           17    3301
XP_005276276                                                           17    4312
XP_005263905                                                           17    4312
XP_005275986                                                           17    4312
NP_001160022                                                           16    5631
NP_000193                                                              16    5631
NP_006114                                                              16    5631
NP_057232                                                              16    5631
NP_063937                                                              16    5631
XP_006723297                                                           16    5631
XP_006723296                                                           16    5631
XP_005259020                                                           16    5631
NP_002372                                                              16    7355
NP_542411                                                              16    7355
NP_001156863                                                           16    7355
NP_001027449                                                           16    7355
NP_077278                                                              16    7355
NP_002283                                                              16    7355
XP_006715347                                                           16    7355
XP_006715346                                                           16    7355
XP_006715345                                                           16    7355
XP_005265184                                                           16    7355
NP_057452                                                              15    9605
NP_061152                                                              15    9605
NP_891847                                                              15    9605
NP_780775                                                              15    9605
NP_001230199                                                           15    9605
NP_055176                                                              15    9605
NP_612152                                                              15    9605
NP_001230200                                                           15    9605
NP_057279                                                              15    9605
NP_001271188                                                           15    9605
XP_005276293                                                           15    9605
XP_006725001                                                           15    9605
XP_006716112                                                           15    9605
XP_005250550                                                           15    9605
XP_006715715                                                           15    9605
XP_005264833                                                           15    9605
XP_005276006                                                           15    9605
NP_003686                                                              15    9605
>NP_001257436
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PTSSRFQNT 9
           PT+SRFQNT
Sbjct: 646 PTASRFQNT 654
>NP_001257437
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PTSSRFQNT 9
           PT+SRFQNT
Sbjct: 646 PTASRFQNT 654
>NP_006281
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PTSSRFQNT 9
           PT+SRFQNT
Sbjct: 646 PTASRFQNT 654
>XP_006715618
          Length = 577

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PTSSRFQNT 9
           PT+SRFQNT
Sbjct: 433 PTASRFQNT 441
>XP_005267176
          Length = 790

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PTSSRFQNT 9
           PT+SRFQNT
Sbjct: 646 PTASRFQNT 654
>NP_001185744
          Length = 1773

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1624 PTSSTFQET 1632
>XP_005275558
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>XP_005275391
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>XP_005275259
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>XP_005274965
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>XP_005272815
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>XP_005274885
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>XP_005248836
          Length = 1776

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    PTSSRFQNT 9
            PTSS FQ T
Sbjct: 1627 PTSSTFQET 1635
>NP_054865
          Length = 243

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PTSSRFQN 8
          P SSR+QN
Sbjct: 90 PASSRYQN 97
>NP_115852
          Length = 243

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PTSSRFQN 8
          P SSR+QN
Sbjct: 90 PASSRYQN 97
>NP_115853
          Length = 243

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PTSSRFQN 8
          P SSR+QN
Sbjct: 90 PASSRYQN 97
>XP_005250619
          Length = 243

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PTSSRFQN 8
          P SSR+QN
Sbjct: 90 PASSRYQN 97
>NP_001087199
          Length = 578

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PTSSRFQN 8
           P+SS FQN
Sbjct: 388 PSSSSFQN 395
>XP_005276276
          Length = 302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSSRFQNT 9
          TSSR QNT
Sbjct: 13 TSSRNQNT 20
>XP_005263905
          Length = 302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSSRFQNT 9
          TSSR QNT
Sbjct: 13 TSSRNQNT 20
>XP_005275986
          Length = 302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSSRFQNT 9
          TSSR QNT
Sbjct: 13 TSSRNQNT 20
>NP_001160022
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  PTSSRFQNT 9
          P+S +++NT
Sbjct: 70 PSSEKYENT 78
>NP_000193
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PTSSRFQNT 9
           P+S +++NT
Sbjct: 160 PSSEKYENT 168
>NP_006114
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PTSSRFQNT 9
           P+S +++NT
Sbjct: 160 PSSEKYENT 168
>NP_057232
          Length = 2161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    PTSSRFQN 8
            P SS FQN
Sbjct: 1936 PVSSLFQN 1943
>NP_063937
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PTSSRFQNT 9
           PTSS +Q+T
Sbjct: 465 PTSSDWQST 473
>XP_006723297
          Length = 2152

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    PTSSRFQN 8
            P SS FQN
Sbjct: 1927 PVSSLFQN 1934
>XP_006723296
          Length = 2161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    PTSSRFQN 8
            P SS FQN
Sbjct: 1936 PVSSLFQN 1943
>XP_005259020
          Length = 2169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    PTSSRFQN 8
            P SS FQN
Sbjct: 1944 PVSSLFQN 1951
>NP_002372
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSRFQNT 9
           SSRFQ T
Sbjct: 255 SSRFQET 261
>NP_542411
          Length = 1736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PTSSRFQ 7
           PT+ RFQ
Sbjct: 322 PTADRFQ 328
>NP_001156863
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TSSRFQN 8
           TSS+F+N
Sbjct: 209 TSSKFEN 215
>NP_001027449
          Length = 130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PTSSRFQN 8
          PTS+RF +
Sbjct: 54 PTSTRFSD 61
>NP_077278
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PTSSRFQN 8
          PTS+RF +
Sbjct: 54 PTSTRFSD 61
>NP_002283
          Length = 1798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PTSSRFQN 8
           P SSR QN
Sbjct: 231 PYSSRIQN 238
>XP_006715347
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TSSRFQN 8
           TSS+F+N
Sbjct: 209 TSSKFEN 215
>XP_006715346
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TSSRFQN 8
           TSS+F+N
Sbjct: 209 TSSKFEN 215
>XP_006715345
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TSSRFQN 8
           TSS+F+N
Sbjct: 209 TSSKFEN 215
>XP_005265184
          Length = 1798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PTSSRFQN 8
           P SSR QN
Sbjct: 231 PYSSRIQN 238
>NP_057452
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PTSSRF 6
          PTS+RF
Sbjct: 43 PTSTRF 48
>NP_061152
          Length = 1858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PTSSRFQN 8
            P+SS +QN
Sbjct: 1552 PSSSYYQN 1559
>NP_891847
          Length = 1858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PTSSRFQN 8
            P+SS +QN
Sbjct: 1552 PSSSYYQN 1559
>NP_780775
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   PTSSRFQN 8
           P S  FQN
Sbjct: 722 PVSEEFQN 729
>NP_001230199
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   PTSSRFQN 8
           P S  FQN
Sbjct: 796 PVSEEFQN 803
>NP_055176
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   PTSSRFQN 8
           P S  FQN
Sbjct: 796 PVSEEFQN 803
>NP_612152
          Length = 2849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PTSSRFQNT 9
            P+SSR+ +T
Sbjct: 1946 PSSSRYLHT 1954
>NP_001230200
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   PTSSRFQN 8
           P S  FQN
Sbjct: 796 PVSEEFQN 803
>NP_057279
          Length = 1780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PTSSRFQ 7
           P SS+FQ
Sbjct: 289 PVSSKFQ 295
>NP_001271188
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PTSSRFQ 7
           P SS+FQ
Sbjct: 289 PVSSKFQ 295
>XP_005276293
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SRFQNT 9
           S+FQNT
Sbjct: 342 SKFQNT 347
>XP_006725001
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  PTSSRFQ 7
          PT+ RFQ
Sbjct: 67 PTTPRFQ 73
>XP_006716112
          Length = 1816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PTSSRFQN 8
            P+SS +QN
Sbjct: 1510 PSSSYYQN 1517
>XP_005250550
          Length = 1858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PTSSRFQN 8
            P+SS +QN
Sbjct: 1552 PSSSYYQN 1559
>XP_006715715
          Length = 2023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PTSSRFQNT 9
            P+SSR+ +T
Sbjct: 1898 PSSSRYLHT 1906
>XP_005264833
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SRFQNT 9
           S+FQNT
Sbjct: 342 SKFQNT 347
>XP_005276006
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SRFQNT 9
           S+FQNT
Sbjct: 342 SKFQNT 347
>NP_003686
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  PTSSRFQNT 9
          P SSRF  T
Sbjct: 39 PASSRFCKT 47
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.112    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 549,711
Number of extensions: 1274
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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