Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004450                                                              17    2528
NP_872579                                                              17    2528
XP_005257218                                                           17    2528
XP_005257217                                                           17    2528
XP_005257216                                                           17    2528
XP_005257215                                                           17    2528
XP_005257214                                                           17    2528
XP_005257213                                                           17    2528
XP_005257212                                                           17    2528
XP_006721834                                                           17    2528
XP_005257211                                                           17    2528
XP_005257210                                                           17    2528
XP_005257209                                                           17    2528
XP_005257208                                                           17    2528
XP_006721833                                                           17    2528
XP_005257207                                                           17    2528
NP_056994                                                              17    4312
XP_005264407                                                           17    4312
XP_005264406                                                           17    4312
XP_005264405                                                           17    4312
NP_060678                                                              16    5631
NP_997198                                                              16    5631
NP_001013663                                                           16    5631
XP_005256756                                                           16    5631
XP_005245361                                                           16    5631
XP_005245360                                                           16    5631
XP_005245359                                                           16    5631
NP_001751                                                              16    7355
NP_001129489                                                           16    7355
NP_001274356                                                           16    7355
NP_115689                                                              16    7355
XP_006717377                                                           16    7355
XP_006717376                                                           16    7355
XP_006717375                                                           16    7355
NP_003925                                                              16    7355
NP_001121636                                                           15    9605
NP_065750                                                              15    9605
NP_000323                                                              15    9605
NP_004949                                                              15    9605
NP_951038                                                              15    9605
NP_001159817                                                           15    9605
NP_055752                                                              15    9605
NP_001230123                                                           15    9605
NP_001244904                                                           15    9605
NP_001244905                                                           15    9605
NP_001124488                                                           15    9605
NP_663622                                                              15    9605
NP_036259                                                              15    9605
NP_078831                                                              15    9605
NP_036294                                                              15    9605
XP_006717782                                                           15    9605
XP_006717103                                                           15    9605
XP_006717102                                                           15    9605
XP_005251947                                                           15    9605
XP_006717101                                                           15    9605
XP_006717100                                                           15    9605
XP_005251945                                                           15    9605
XP_006717099                                                           15    9605
XP_005251944                                                           15    9605
XP_005251943                                                           15    9605
XP_005251162                                                           15    9605
XP_005251161                                                           15    9605
XP_005251160                                                           15    9605
XP_005251159                                                           15    9605
XP_005245421                                                           15    9605
XP_006711532                                                           15    9605
XP_005245420                                                           15    9605
XP_005263496                                                           15    9605
XP_005263495                                                           15    9605
NP_001138560                                                           15    9605
NP_055643                                                              15    9605
>NP_004450
          Length = 2903

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2487 PGQQSQVQT 2495
>NP_872579
          Length = 2920

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2361 PGQQSQVQT 2369
>XP_005257218
          Length = 2957

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>XP_005257217
          Length = 2961

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2487 PGQQSQVQT 2495
>XP_005257216
          Length = 3015

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>XP_005257215
          Length = 3032

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2415 PGQQSQVQT 2423
>XP_005257214
          Length = 3094

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2477 PGQQSQVQT 2485
>XP_005257213
          Length = 3095

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2478 PGQQSQVQT 2486
>XP_005257212
          Length = 3095

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2478 PGQQSQVQT 2486
>XP_006721834
          Length = 3100

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>XP_005257211
          Length = 3100

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>XP_005257210
          Length = 3104

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2487 PGQQSQVQT 2495
>XP_005257209
          Length = 3148

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>XP_005257208
          Length = 3157

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2540 PGQQSQVQT 2548
>XP_006721833
          Length = 3158

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>XP_005257207
          Length = 3158

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            P +QSQ+QT
Sbjct: 2541 PGQQSQVQT 2549
>NP_056994
          Length = 746

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           P R++QL+T
Sbjct: 538 PEREAQLET 546
>XP_005264407
          Length = 587

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           P R++QL+T
Sbjct: 379 PEREAQLET 387
>XP_005264406
          Length = 634

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           P R++QL+T
Sbjct: 391 PEREAQLET 399
>XP_005264405
          Length = 781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           P R++QL+T
Sbjct: 538 PEREAQLET 546
>NP_060678
          Length = 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           P+R++QLQ
Sbjct: 300 PARETQLQ 307
>NP_997198
          Length = 449

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSRQSQLQT 9
           PSR+  LQT
Sbjct: 429 PSREKVLQT 437
>NP_001013663
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSRQSQLQT 9
           P  QSQ+QT
Sbjct: 259 PGLQSQVQT 267
>XP_005256756
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PSRQSQLQ 8
          P R SQLQ
Sbjct: 17 PGRMSQLQ 24
>XP_005245361
          Length = 345

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           P+R++QLQ
Sbjct: 259 PARETQLQ 266
>XP_005245360
          Length = 353

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           P+R++QLQ
Sbjct: 259 PARETQLQ 266
>XP_005245359
          Length = 394

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           P+R++QLQ
Sbjct: 300 PARETQLQ 307
>NP_001751
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           P+R++QLQ
Sbjct: 93  PTRKAQLQ 100
>NP_001129489
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  PSRQSQLQ 8
          P+R++QLQ
Sbjct: 12 PTRKAQLQ 19
>NP_001274356
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  PSRQSQLQ 8
          P+R++QLQ
Sbjct: 43 PTRKAQLQ 50
>NP_115689
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PSRQSQLQ 8
          P+R+ QLQ
Sbjct: 85 PTREKQLQ 92
>XP_006717377
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           PS+QSQ Q+
Sbjct: 308 PSQQSQPQS 316
>XP_006717376
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           PS+QSQ Q+
Sbjct: 416 PSQQSQPQS 424
>XP_006717375
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           PS+QSQ Q+
Sbjct: 502 PSQQSQPQS 510
>NP_003925
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           PS+QSQ Q+
Sbjct: 503 PSQQSQPQS 511
>NP_001121636
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           PS++SQL+
Sbjct: 168 PSQRSQLE 175
>NP_065750
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RQSQLQ 8
           RQSQLQ
Sbjct: 187 RQSQLQ 192
>NP_000323
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSRQSQLQ 8
           PS++SQL+
Sbjct: 168 PSQRSQLE 175
>NP_004949
          Length = 2549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            PSR++ L+T
Sbjct: 1130 PSRKAALET 1138
>NP_951038
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PSRQSQLQT 9
           P R  QLQT
Sbjct: 184 PQRLPQLQT 192
>NP_001159817
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  PSRQSQLQT 9
          P R  QLQT
Sbjct: 75 PQRLPQLQT 83
>NP_055752
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PSRQSQL 7
            PSR SQL
Sbjct: 1008 PSRPSQL 1014
>NP_001230123
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PSRQSQL 7
           PSR SQL
Sbjct: 398 PSRPSQL 404
>NP_001244904
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 445 PPRQVQLQ 452
>NP_001244905
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 314 PPRQVQLQ 321
>NP_001124488
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 415 PPRQVQLQ 422
>NP_663622
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQSQLQT 9
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>NP_036259
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 415 PPRQVQLQ 422
>NP_078831
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSRQSQLQ 8
           P+R SQLQ
Sbjct: 190 PNRFSQLQ 197
>NP_036294
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSRQSQLQ 8
           P+R SQLQ
Sbjct: 190 PNRFSQLQ 197
>XP_006717782
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PSRQSQL 7
           PSR SQL
Sbjct: 965 PSRPSQL 971
>XP_006717103
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 391 PPRQVQLQ 398
>XP_006717102
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 418 PPRQVQLQ 425
>XP_005251947
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 415 PPRQVQLQ 422
>XP_006717101
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 423 PPRQVQLQ 430
>XP_006717100
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 486 PPRQVQLQ 493
>XP_005251945
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 486 PPRQVQLQ 493
>XP_006717099
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 486 PPRQVQLQ 493
>XP_005251944
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 481 PPRQVQLQ 488
>XP_005251943
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSRQSQLQ 8
           P RQ QLQ
Sbjct: 486 PPRQVQLQ 493
>XP_005251162
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQSQLQT 9
           SR+S++QT
Sbjct: 276 SRESKMQT 283
>XP_005251161
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQSQLQT 9
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>XP_005251160
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQSQLQT 9
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>XP_005251159
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQSQLQT 9
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>XP_005245421
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RQSQLQ 8
           RQSQLQ
Sbjct: 187 RQSQLQ 192
>XP_006711532
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RQSQLQ 8
           RQSQLQ
Sbjct: 187 RQSQLQ 192
>XP_005245420
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RQSQLQ 8
           RQSQLQ
Sbjct: 193 RQSQLQ 198
>XP_005263496
          Length = 2322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           PSR++ L+T
Sbjct: 903 PSRKAALET 911
>XP_005263495
          Length = 2549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PSRQSQLQT 9
            PSR++ L+T
Sbjct: 1130 PSRKAALET 1138
>NP_001138560
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQSQLQT 9
           SR+S++QT
Sbjct: 381 SRESKMQT 388
>NP_055643
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PSRQSQLQT 9
           PS+Q+Q+ T
Sbjct: 412 PSQQAQIVT 420
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.108    0.270 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 458,657
Number of extensions: 861
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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