Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004110                                                              18    1935
NP_003740                                                              17    4312
NP_689963                                                              17    4312
XP_005250282                                                           17    4312
XP_006715969                                                           17    4312
XP_006715968                                                           17    4312
XP_005250281                                                           17    4312
XP_005250280                                                           17    4312
NP_001006608                                                           16    5631
NP_955372                                                              16    5631
NP_055649                                                              16    5631
XP_005275724                                                           16    5631
XP_005275722                                                           16    5631
XP_005275721                                                           16    5631
XP_006725345                                                           16    5631
XP_006725344                                                           16    5631
XP_005275719                                                           16    5631
XP_006725343                                                           16    5631
XP_006725342                                                           16    5631
XP_005275717                                                           16    5631
XP_005275716                                                           16    5631
XP_005257941                                                           16    5631
XP_005257940                                                           16    5631
XP_006722274                                                           16    5631
XP_006722273                                                           16    5631
XP_005257939                                                           16    5631
XP_006722272                                                           16    5631
XP_005257937                                                           16    5631
XP_005257936                                                           16    5631
XP_005257935                                                           16    5631
XP_006722271                                                           16    5631
NP_001171655                                                           16    7355
NP_000346                                                              16    7355
NP_005090                                                              15    9605
NP_001138817                                                           15    9605
NP_848611                                                              15    9605
NP_001017922                                                           15    9605
NP_061008                                                              15    9605
NP_001138816                                                           15    9605
NP_116227                                                              15    9605
NP_001138815                                                           15    9605
XP_005259413                                                           15    9605
XP_006723511                                                           15    9605
XP_005259411                                                           15    9605
XP_006723510                                                           15    9605
XP_006712361                                                           15    9605
XP_005246377                                                           15    9605
XP_006710376                                                           15    9605
XP_005270472                                                           15    9605
>NP_004110
          Length = 993

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  SITLQVLV 9
          SITLQVLV
Sbjct: 88 SITLQVLV 95
>NP_003740
          Length = 1338

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+TLQ++
Sbjct: 236 PSVTLQLM 243
>NP_689963
          Length = 885

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PSITLQVLV 9
           P+I+L+VLV
Sbjct: 309 PTISLEVLV 317
>XP_005250282
          Length = 693

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PSITLQVLV 9
           P+I+L+VLV
Sbjct: 309 PTISLEVLV 317
>XP_006715969
          Length = 703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PSITLQVLV 9
           P+I+L+VLV
Sbjct: 127 PTISLEVLV 135
>XP_006715968
          Length = 752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PSITLQVLV 9
           P+I+L+VLV
Sbjct: 309 PTISLEVLV 317
>XP_005250281
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PSITLQVLV 9
           P+I+L+VLV
Sbjct: 221 PTISLEVLV 229
>XP_005250280
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PSITLQVLV 9
           P+I+L+VLV
Sbjct: 221 PTISLEVLV 229
>NP_001006608
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>NP_955372
          Length = 1634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>NP_055649
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005275724
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005275722
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005275721
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006725345
          Length = 1600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006725344
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 510 PSVTVQLL 517
>XP_005275719
          Length = 1625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006725343
          Length = 1635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006725342
          Length = 1651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005275717
          Length = 1665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005275716
          Length = 1676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005257941
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005257940
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006722274
          Length = 1576

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006722273
          Length = 1600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005257939
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 510 PSVTVQLL 517
>XP_006722272
          Length = 1635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005257937
          Length = 1651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005257936
          Length = 1665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_005257935
          Length = 1676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>XP_006722271
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PSITLQVL 8
           PS+T+Q+L
Sbjct: 604 PSVTVQLL 611
>NP_001171655
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SITLQVL 8
           S+TLQVL
Sbjct: 304 SVTLQVL 310
>NP_000346
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SITLQVL 8
           S+TLQVL
Sbjct: 331 SVTLQVL 337
>NP_005090
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ITLQVLV 9
           +TLQVLV
Sbjct: 781 LTLQVLV 787
>NP_001138817
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSITLQVLV 9
           PS TLQ ++
Sbjct: 156 PSFTLQQII 164
>NP_848611
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PSITLQVL 8
           P+I LQ+L
Sbjct: 423 PAIVLQIL 430
>NP_001017922
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SITLQVL 8
           S+TLQ+L
Sbjct: 108 SVTLQIL 114
>NP_061008
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SITLQVL 8
           S+TLQ+L
Sbjct: 108 SVTLQIL 114
>NP_001138816
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSITLQVLV 9
           PS TLQ ++
Sbjct: 156 PSFTLQQII 164
>NP_116227
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSITLQVLV 9
           PS TLQ ++
Sbjct: 156 PSFTLQQII 164
>NP_001138815
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSITLQVLV 9
           PS TLQ ++
Sbjct: 157 PSFTLQQII 165
>XP_005259413
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PSITLQVLV 9
          PS TLQ ++
Sbjct: 52 PSFTLQQII 60
>XP_006723511
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PSITLQVLV 9
          PS TLQ ++
Sbjct: 52 PSFTLQQII 60
>XP_005259411
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSITLQVLV 9
           PS TLQ ++
Sbjct: 124 PSFTLQQII 132
>XP_006723510
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PSITLQVLV 9
           PS TLQ ++
Sbjct: 157 PSFTLQQII 165
>XP_006712361
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITLQVLV 9
          +TLQ+LV
Sbjct: 11 VTLQILV 17
>XP_005246377
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITLQVLV 9
          +TLQ+LV
Sbjct: 11 VTLQILV 17
>XP_006710376
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SITLQVL 8
           S+TLQ+L
Sbjct: 108 SVTLQIL 114
>XP_005270472
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SITLQVL 8
           S+TLQ+L
Sbjct: 169 SVTLQIL 175
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.139    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,183
Number of extensions: 552
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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