Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              20     509
XP_005251512                                                           20     509
NP_982278                                                              17    2528
NP_036290                                                              17    3301
XP_005266393                                                           17    3301
NP_998761                                                              17    4312
NP_004691                                                              16    5631
NP_057613                                                              16    5631
NP_001229766                                                           16    5631
NP_036437                                                              16    5631
NP_001074003                                                           16    5631
XP_005254452                                                           16    5631
XP_005254451                                                           16    5631
XP_006719898                                                           16    5631
XP_006719897                                                           16    5631
XP_006719896                                                           16    5631
XP_006719895                                                           16    5631
XP_005266476                                                           16    5631
XP_006718223                                                           16    5631
XP_006718222                                                           16    5631
NP_660143                                                              16    7355
NP_003049                                                              16    7355
NP_001193733                                                           16    7355
NP_055045                                                              16    7355
NP_068812                                                              16    7355
NP_001247432                                                           16    7355
NP_001276903                                                           16    7355
NP_001247431                                                           16    7355
XP_003960167                                                           16    7355
XP_005267163                                                           16    7355
XP_003846269                                                           16    7355
XP_003846670                                                           16    7355
NP_001116212                                                           15    9605
NP_001116214                                                           15    9605
NP_000116                                                              15    9605
NP_001116213                                                           15    9605
NP_001155967                                                           15    9605
NP_001155968                                                           15    9605
NP_062542                                                              15    9605
NP_001278159                                                           15    9605
NP_001278170                                                           15    9605
NP_004321                                                              15    9605
NP_057346                                                              15    9605
NP_699200                                                              15    9605
NP_653165                                                              15    9605
NP_001073887                                                           15    9605
NP_002557                                                              15    9605
NP_060371                                                              15    9605
NP_001035754                                                           15    9605
XP_005254664                                                           15    9605
XP_006719600                                                           15    9605
XP_005253969                                                           15    9605
XP_006719599                                                           15    9605
XP_006719598                                                           15    9605
XP_006719597                                                           15    9605
XP_005253967                                                           15    9605
XP_006719596                                                           15    9605
XP_006719595                                                           15    9605
XP_006719594                                                           15    9605
XP_006719528                                                           15    9605
XP_005253963                                                           15    9605
XP_005253962                                                           15    9605
XP_006715438                                                           15    9605
XP_006715437                                                           15    9605
XP_005247225                                                           15    9605
XP_005247224                                                           15    9605
XP_005271148                                                           15    9605
NP_001137291                                                           15    9605
NP_612468                                                              15    9605
NP_997218                                                              15    9605
NP_570603                                                              15    9605
NP_055018                                                              15    9605
>NP_004963
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PSFMDLALR 9
            PSF DLALR
Sbjct: 1114 PSFRDLALR 1122
>XP_005251512
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PSFMDLALR 9
            PSF DLALR
Sbjct: 1114 PSFRDLALR 1122
>NP_982278
          Length = 295

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PSFMDLALR 9
           PSF+ +ALR
Sbjct: 96  PSFLGIALR 104
>NP_036290
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PSFMDL 6
           PSFMDL
Sbjct: 150 PSFMDL 155
>XP_005266393
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PSFMDL 6
           PSFMDL
Sbjct: 150 PSFMDL 155
>NP_998761
          Length = 517

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PS MD AL+
Sbjct: 423 PSIMDFALQ 431
>NP_004691
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           PSF +LAL
Sbjct: 374 PSFRELAL 381
>NP_057613
          Length = 1188

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+DLAL
Sbjct: 780 SFLDLAL 786
>NP_001229766
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           P+FM LAL
Sbjct: 125 PTFMGLAL 132
>NP_036437
          Length = 939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           P+FM LAL
Sbjct: 125 PTFMGLAL 132
>NP_001074003
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PSF + ALR
Sbjct: 970 PSFKEAALR 978
>XP_005254452
          Length = 2188

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PSF + ALR
Sbjct: 970 PSFKEAALR 978
>XP_005254451
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PSF + ALR
Sbjct: 970 PSFKEAALR 978
>XP_006719898
          Length = 763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+DLAL
Sbjct: 740 SFLDLAL 746
>XP_006719897
          Length = 1148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+DLAL
Sbjct: 740 SFLDLAL 746
>XP_006719896
          Length = 1005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+DLAL
Sbjct: 597 SFLDLAL 603
>XP_006719895
          Length = 1082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+DLAL
Sbjct: 674 SFLDLAL 680
>XP_005266476
          Length = 1148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+DLAL
Sbjct: 740 SFLDLAL 746
>XP_006718223
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           P+FM LAL
Sbjct: 127 PTFMGLAL 134
>XP_006718222
          Length = 942

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           P+FM LAL
Sbjct: 127 PTFMGLAL 134
>NP_660143
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SFM+LAL
Sbjct: 345 SFMELAL 351
>NP_003049
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PSFMDL 6
           PSF+DL
Sbjct: 333 PSFLDL 338
>NP_001193733
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SFM+LAL
Sbjct: 309 SFMELAL 315
>NP_055045
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F DLAL
Sbjct: 588 PLFFDLAL 595
>NP_068812
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PSFMDL 6
           PSF+DL
Sbjct: 336 PSFLDL 341
>NP_001247432
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F DLAL
Sbjct: 249 PLFFDLAL 256
>NP_001276903
          Length = 579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           P+F  LALR
Sbjct: 499 PAFRTLALR 507
>NP_001247431
          Length = 589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F DLAL
Sbjct: 550 PLFFDLAL 557
>XP_003960167
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           P+F  LALR
Sbjct: 582 PAFRTLALR 590
>XP_005267163
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PSFMDL 6
           PSF+DL
Sbjct: 205 PSFLDL 210
>XP_003846269
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           P+F  LALR
Sbjct: 582 PAFRTLALR 590
>XP_003846670
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           P+F  LALR
Sbjct: 589 PAFRTLALR 597
>NP_001116212
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 365 PGFVDLTL 372
>NP_001116214
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 365 PGFVDLTL 372
>NP_000116
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 365 PGFVDLTL 372
>NP_001116213
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 365 PGFVDLTL 372
>NP_001155967
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+D+AL
Sbjct: 168 SFLDMAL 174
>NP_001155968
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+D+AL
Sbjct: 168 SFLDMAL 174
>NP_062542
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SFMDLAL 8
           SF+D+AL
Sbjct: 168 SFLDMAL 174
>NP_001278159
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 367 PGFVDLTL 374
>NP_001278170
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 364 PGFVDLTL 371
>NP_004321
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PSFMDLAL 8
          P+F DLA+
Sbjct: 75 PAFCDLAV 82
>NP_057346
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  FMDLALR 9
          F DLALR
Sbjct: 20 FWDLALR 26
>NP_699200
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  PSFMDLA 7
          P+F DLA
Sbjct: 18 PTFQDLA 24
>NP_653165
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PSFMDL 6
           PSF+DL
Sbjct: 113 PSFIDL 118
>NP_001073887
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PSFMDLA 7
           P+F DLA
Sbjct: 867 PTFQDLA 873
>NP_002557
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PSFMDLA 7
           PSF D+A
Sbjct: 283 PSFADIA 289
>NP_060371
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P FMD+ L
Sbjct: 230 PPFMDILL 237
>NP_001035754
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PSFMDLA 7
           PSF D+A
Sbjct: 703 PSFADIA 709
>XP_005254664
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PSFMDLAL 8
          P+F DLA+
Sbjct: 75 PAFCDLAV 82
>XP_006719600
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 352 PSWLDLA 358
>XP_005253969
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 352 PSWLDLA 358
>XP_006719599
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 213 PSWLDLA 219
>XP_006719598
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 213 PSWLDLA 219
>XP_006719597
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 213 PSWLDLA 219
>XP_005253967
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 352 PSWLDLA 358
>XP_006719596
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 344 PSWLDLA 350
>XP_006719595
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 346 PSWLDLA 352
>XP_006719594
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PSFMDLA 7
           PS++DLA
Sbjct: 352 PSWLDLA 358
>XP_006719528
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P FMD+ L
Sbjct: 302 PPFMDILL 309
>XP_005253963
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P FMD+ L
Sbjct: 162 PPFMDILL 169
>XP_005253962
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P FMD+ L
Sbjct: 302 PPFMDILL 309
>XP_006715438
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 192 PGFVDLTL 199
>XP_006715437
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P F+DL L
Sbjct: 365 PGFVDLTL 372
>XP_005247225
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PSF+  ALR
Sbjct: 227 PSFLRQALR 235
>XP_005247224
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PSF+  ALR
Sbjct: 227 PSFLRQALR 235
>XP_005271148
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PSFMDLA 7
           P+F DLA
Sbjct: 867 PTFQDLA 873
>NP_001137291
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PSFMDLAL 8
           P FMD+ L
Sbjct: 302 PPFMDILL 309
>NP_612468
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PSFMDLA 7
           PSF D+A
Sbjct: 112 PSFSDIA 118
>NP_997218
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PSFMDLALR 9
           PSF+  ALR
Sbjct: 227 PSFLRQALR 235
>NP_570603
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           P+FM LAL
Sbjct: 125 PTFMCLAL 132
>NP_055018
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PSFMDLAL 8
           P+FM LAL
Sbjct: 125 PTFMCLAL 132
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.145    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,679
Number of extensions: 734
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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