Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     390
XP_005262424                                                           20     390
NP_001399                                                              17    4312
XP_006710468                                                           17    4312
XP_005270637                                                           17    4312
NP_001273983                                                           16    7355
NP_003430                                                              16    7355
NP_056374                                                              16    7355
XP_006722501                                                           16    7355
XP_005258301                                                           16    7355
XP_005258300                                                           16    7355
XP_005250622                                                           16    7355
XP_006716175                                                           16    7355
NP_005156                                                              15    9605
NP_149052                                                              15    9605
XP_005258006                                                           15    9605
XP_005258004                                                           15    9605
XP_006710201                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PRESAMATS 9
            PRES+MATS
Sbjct: 1499 PRESSMATS 1507
>XP_005262424
          Length = 2875

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PRESAMATS 9
            PRES+MATS
Sbjct: 1294 PRESSMATS 1302
>NP_001399
          Length = 2923

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PRESAMAT 8
           PR SA+AT
Sbjct: 267 PRRSALAT 274
>XP_006710468
          Length = 2916

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PRESAMAT 8
           PR SA+AT
Sbjct: 267 PRRSALAT 274
>XP_005270637
          Length = 2921

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PRESAMAT 8
           PR SA+AT
Sbjct: 267 PRRSALAT 274
>NP_001273983
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PRESAMATS 9
           PR+ AMA++
Sbjct: 173 PRDQAMASA 181
>NP_003430
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PRESAMATS 9
           PR+ AMA++
Sbjct: 209 PRDQAMASA 217
>NP_056374
          Length = 1596

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RESAMATS 9
           RE+ MATS
Sbjct: 544 REAVMATS 551
>XP_006722501
          Length = 1403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RESAMATS 9
           RE+ MATS
Sbjct: 544 REAVMATS 551
>XP_005258301
          Length = 1539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RESAMATS 9
           RE+ MATS
Sbjct: 544 REAVMATS 551
>XP_005258300
          Length = 1596

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RESAMATS 9
           RE+ MATS
Sbjct: 544 REAVMATS 551
>XP_005250622
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PRESAMATS 9
           PR+ AMA++
Sbjct: 209 PRDQAMASA 217
>XP_006716175
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PRESAMATS 9
           PR+ AMA++
Sbjct: 209 PRDQAMASA 217
>NP_005156
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PRESAMAT 8
           P E AMAT
Sbjct: 246 PEEIAMAT 253
>NP_149052
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESAMATS 9
           ESAMAT+
Sbjct: 650 ESAMATA 656
>XP_005258006
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PRESAMAT 8
           P E AMAT
Sbjct: 246 PEEIAMAT 253
>XP_005258004
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PRESAMAT 8
           P E AMAT
Sbjct: 333 PEEIAMAT 340
>XP_006710201
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PRESAMATS 9
           PR  A+ATS
Sbjct: 243 PRAPAIATS 251
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296   0.0999    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,407
Number of extensions: 262
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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