Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002370                                                              18    1482
NP_001254772                                                           17    4312
NP_004889                                                              17    4312
NP_849188                                                              17    4312
XP_005262456                                                           17    4312
XP_006714117                                                           17    4312
XP_005265844                                                           17    4312
NP_001132974                                                           17    4312
NP_001132972                                                           17    4312
NP_001132973                                                           17    4312
NP_001094287                                                           16    7355
NP_001009881                                                           16    7355
NP_001229836                                                           16    7355
NP_056993                                                              16    7355
NP_056084                                                              16    7355
NP_663628                                                              16    7355
NP_653181                                                              16    7355
NP_001243537                                                           16    7355
NP_001243533                                                           16    7355
NP_001243538                                                           16    7355
XP_005276697                                                           16    7355
XP_005276696                                                           16    7355
XP_006726829                                                           16    7355
XP_006726828                                                           16    7355
XP_005276694                                                           16    7355
XP_006726827                                                           16    7355
XP_005276693                                                           16    7355
XP_006722653                                                           16    7355
XP_005270740                                                           16    7355
XP_005270739                                                           16    7355
XP_006710563                                                           16    7355
XP_005270738                                                           16    7355
XP_005270737                                                           16    7355
XP_005270736                                                           16    7355
XP_005270735                                                           16    7355
XP_006710562                                                           16    7355
XP_006710561                                                           16    7355
XP_005270733                                                           16    7355
NP_057511                                                              16    7355
NP_006749                                                              15    9605
XP_006726862                                                           15    9605
XP_006723991                                                           15    9605
XP_005267972                                                           15    9605
XP_005267971                                                           15    9605
XP_006720278                                                           15    9605
XP_005267970                                                           15    9605
NP_065766                                                              15    9605
>NP_002370
          Length = 496

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   PQDSVQSAS 9
           PQDSVQ  S
Sbjct: 157 PQDSVQDVS 165
>NP_001254772
          Length = 846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           PQ+S QSA+
Sbjct: 683 PQNSTQSAA 691
>NP_004889
          Length = 846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           PQ+S QSA+
Sbjct: 683 PQNSTQSAA 691
>NP_849188
          Length = 2400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PQDSVQSAS 9
           P+D V SAS
Sbjct: 476 PEDGVDSAS 484
>XP_005262456
          Length = 255

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QDSVQSA 8
          QDS+QSA
Sbjct: 33 QDSIQSA 39
>XP_006714117
          Length = 846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           PQ+S QSA+
Sbjct: 683 PQNSTQSAA 691
>XP_005265844
          Length = 846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           PQ+S QSA+
Sbjct: 683 PQNSTQSAA 691
>NP_001132974
          Length = 226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QDSVQSA 8
          QDS+QSA
Sbjct: 4  QDSIQSA 10
>NP_001132972
          Length = 255

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QDSVQSA 8
          QDS+QSA
Sbjct: 33 QDSIQSA 39
>NP_001132973
          Length = 226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  QDSVQSA 8
          QDS+QSA
Sbjct: 4  QDSIQSA 10
>NP_001094287
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>NP_001009881
          Length = 1645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1435 PQNSSQSAA 1443
>NP_001229836
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>NP_056993
          Length = 2371

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    PQDSVQSA 8
            P+D VQSA
Sbjct: 2033 PKDIVQSA 2040
>NP_056084
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1434 PQNSSQSAA 1442
>NP_663628
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>NP_653181
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           P+DS+Q +S
Sbjct: 112 PKDSIQFSS 120
>NP_001243537
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           P+DS+Q +S
Sbjct: 112 PKDSIQFSS 120
>NP_001243533
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PQDSVQSAS 9
           P+DS+Q +S
Sbjct: 112 PKDSIQFSS 120
>NP_001243538
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PQDSVQSAS 9
          P+DS+Q +S
Sbjct: 31 PKDSIQFSS 39
>XP_005276697
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PQDSVQSAS 9
           PQD  +SAS
Sbjct: 298 PQDPEESAS 306
>XP_005276696
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 73 PQDPEESAS 81
>XP_006726829
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>XP_006726828
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PQDSVQSAS 9
           PQD  +SAS
Sbjct: 124 PQDPEESAS 132
>XP_005276694
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>XP_006726827
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>XP_005276693
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>XP_006722653
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>XP_005270740
          Length = 1530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1313 PQNSSQSAA 1321
>XP_005270739
          Length = 1541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1324 PQNSSQSAA 1332
>XP_006710563
          Length = 1581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1364 PQNSSQSAA 1372
>XP_005270738
          Length = 1614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1397 PQNSSQSAA 1405
>XP_005270737
          Length = 1640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1430 PQNSSQSAA 1438
>XP_005270736
          Length = 1647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1430 PQNSSQSAA 1438
>XP_005270735
          Length = 1651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1434 PQNSSQSAA 1442
>XP_006710562
          Length = 1652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1435 PQNSSQSAA 1443
>XP_006710561
          Length = 1652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1435 PQNSSQSAA 1443
>XP_005270733
          Length = 1652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    PQDSVQSAS 9
            PQ+S QSA+
Sbjct: 1435 PQNSSQSAA 1443
>NP_057511
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PQDSVQSAS 9
          PQD  +SAS
Sbjct: 87 PQDPEESAS 95
>NP_006749
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PQDSVQSA 8
          PQ+S QSA
Sbjct: 55 PQNSSQSA 62
>XP_006726862
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PQDSVQSA 8
          PQ+S QSA
Sbjct: 55 PQNSSQSA 62
>XP_006723991
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PQDSVQSA 8
          PQ+S QSA
Sbjct: 55 PQNSSQSA 62
>XP_005267972
          Length = 1325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PQDSVQSA 8
           P+DS+Q A
Sbjct: 321 PRDSIQLA 328
>XP_005267971
          Length = 1344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PQDSVQSA 8
           P+DS+Q A
Sbjct: 321 PRDSIQLA 328
>XP_006720278
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PQDSVQSA 8
           P+DS+Q A
Sbjct: 321 PRDSIQLA 328
>XP_005267970
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PQDSVQSA 8
           P+DS+Q A
Sbjct: 321 PRDSIQLA 328
>NP_065766
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PQDSVQSA 8
           P+DS+Q A
Sbjct: 321 PRDSIQLA 328
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285   0.0988    0.238 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 464,883
Number of extensions: 385
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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