Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           18    1135
NP_004439                                                              18    1135
NP_001276865                                                           18    1135
NP_001005862                                                           18    1135
XP_005257197                                                           18    1135
XP_006721828                                                           18    1135
XP_006713469                                                           18    1482
XP_005259254                                                           18    1935
NP_689740                                                              16    7355
XP_006718462                                                           16    7355
XP_005246411                                                           16    7355
XP_005246410                                                           16    7355
NP_689619                                                              15    9605
NP_001139809                                                           15    9605
XP_005268430                                                           15    9605
>NP_001276866
          Length = 1055

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTSIISA
Sbjct: 650 PLTSIISA 657
>NP_004439
          Length = 1255

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTSIISA
Sbjct: 650 PLTSIISA 657
>NP_001276865
          Length = 1240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTSIISA
Sbjct: 635 PLTSIISA 642
>NP_001005862
          Length = 1225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTSIISA
Sbjct: 620 PLTSIISA 627
>XP_005257197
          Length = 1225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTSIISA
Sbjct: 620 PLTSIISA 627
>XP_006721828
          Length = 1336

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTSIISA
Sbjct: 731 PLTSIISA 738
>XP_006713469
          Length = 285

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  PLTSIISAA 9
          P TSI+SAA
Sbjct: 31 PFTSIVSAA 39
>XP_005259254
          Length = 351

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   PLTSIISA 8
           PLTS++SA
Sbjct: 340 PLTSVVSA 347
>NP_689740
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PLTSIIS 7
           PLTSII+
Sbjct: 354 PLTSIIA 360
>XP_006718462
          Length = 4966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    PLTSIISA 8
            P+TS ISA
Sbjct: 3099 PITSTISA 3106
>XP_005246411
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PLTSIIS 7
           PLTSII+
Sbjct: 225 PLTSIIA 231
>XP_005246410
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PLTSIIS 7
           PLTSII+
Sbjct: 306 PLTSIIA 312
>NP_689619
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTSIISA 8
           LTSI+SA
Sbjct: 530 LTSIVSA 536
>NP_001139809
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTSIISA 8
           LTSI+SA
Sbjct: 530 LTSIVSA 536
>XP_005268430
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTSIISA 8
           LTSI+SA
Sbjct: 497 LTSIVSA 503
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.121    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 309,019
Number of extensions: 351
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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