Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_079223                                                              17    3301
XP_006713820                                                           17    3301
XP_005247850                                                           17    3301
XP_005247848                                                           17    3301
XP_006713819                                                           17    3301
XP_005247847                                                           17    3301
XP_006713818                                                           17    3301
XP_006713817                                                           17    3301
XP_006713816                                                           17    3301
XP_005247846                                                           17    3301
XP_005269164                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 200 PLQPSARVS 208
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 200 PLQPSARVS 208
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 200 PLQPSARVS 208
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 200 PLQPSARVS 208
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 210 PLQPSARVS 218
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 210 PLQPSARVS 218
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 210 PLQPSARVS 218
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           PLQ SARVS
Sbjct: 210 PLQPSARVS 218
>NP_079223
          Length = 995

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 480 PVQQSALVS 488
>XP_006713820
          Length = 597

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 480 PVQQSALVS 488
>XP_005247850
          Length = 614

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 480 PVQQSALVS 488
>XP_005247848
          Length = 897

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 480 PVQQSALVS 488
>XP_006713819
          Length = 925

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 394 PVQQSALVS 402
>XP_005247847
          Length = 983

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 468 PVQQSALVS 476
>XP_006713818
          Length = 999

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 468 PVQQSALVS 476
>XP_006713817
          Length = 999

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 468 PVQQSALVS 476
>XP_006713816
          Length = 999

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 468 PVQQSALVS 476
>XP_005247846
          Length = 1011

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLQQSARVS 9
           P+QQSA VS
Sbjct: 480 PVQQSALVS 488
>XP_005269164
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PLQQSARV 8
          PL Q ARV
Sbjct: 8  PLHQRARV 15
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.114    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,839
Number of extensions: 374
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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