Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_001136245                                                           17    3301
NP_001136239                                                           17    3301
NP_001136236                                                           17    3301
NP_001136244                                                           17    3301
NP_001136238                                                           17    3301
NP_001136240                                                           17    3301
NP_001136243                                                           17    3301
NP_001136242                                                           17    3301
NP_001136235                                                           17    3301
NP_001136237                                                           17    3301
NP_001136241                                                           17    3301
NP_149045                                                              17    3301
NP_036232                                                              17    3301
XP_006718013                                                           17    3301
XP_005246489                                                           17    3301
XP_005246488                                                           17    3301
XP_005246487                                                           17    3301
NP_036466                                                              16    5631
NP_003205                                                              16    5631
NP_060082                                                              16    5631
XP_006719555                                                           16    5631
XP_005253638                                                           16    5631
XP_006719554                                                           16    5631
XP_006714538                                                           16    5631
NP_001153115                                                           16    7355
NP_060819                                                              16    7355
NP_001159579                                                           16    7355
NP_005509                                                              16    7355
NP_067636                                                              16    7355
XP_005255016                                                           16    7355
XP_005255015                                                           16    7355
XP_005255014                                                           16    7355
XP_006720666                                                           16    7355
XP_006720665                                                           16    7355
XP_005255012                                                           16    7355
NP_000408                                                              15    9605
NP_005434                                                              15    9605
NP_001276968                                                           15    9605
NP_001276969                                                           15    9605
NP_001276994                                                           15    9605
NP_001122401                                                           15    9605
NP_002933                                                              15    9605
NP_001001974                                                           15    9605
NP_067635                                                              15    9605
NP_001182537                                                           15    9605
NP_006835                                                              15    9605
NP_006368                                                              15    9605
NP_001073890                                                           15    9605
XP_006722755                                                           15    9605
XP_005259774                                                           15    9605
XP_005270078                                                           15    9605
XP_006717998                                                           15    9605
XP_005270077                                                           15    9605
XP_005270076                                                           15    9605
XP_005270075                                                           15    9605
XP_005270074                                                           15    9605
XP_005270073                                                           15    9605
XP_005252503                                                           15    9605
XP_006716779                                                           15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PLQAVDQRD 9
            PLQAV QRD
Sbjct: 2793 PLQAVAQRD 2801
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PLQAVDQRD 9
            PLQAV QRD
Sbjct: 2793 PLQAVAQRD 2801
>NP_001136245
          Length = 1932

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 281 PIQAIDQ 287
>NP_001136239
          Length = 1915

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 266 PIQAIDQ 272
>NP_001136236
          Length = 1957

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136244
          Length = 1677

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136238
          Length = 1952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136240
          Length = 1935

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 281 PIQAIDQ 287
>NP_001136243
          Length = 1682

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 308 PIQAIDQ 314
>NP_001136242
          Length = 1539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136235
          Length = 1962

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 308 PIQAIDQ 314
>NP_001136237
          Length = 1886

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136241
          Length = 1790

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 308 PIQAIDQ 314
>NP_149045
          Length = 1955

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_036232
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLQAVDQR 8
           PL AVD+R
Sbjct: 218 PLNAVDER 225
>XP_006718013
          Length = 1778

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>XP_005246489
          Length = 432

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLQAVDQR 8
           PL AVD+R
Sbjct: 165 PLNAVDER 172
>XP_005246488
          Length = 471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLQAVDQR 8
           PL AVD+R
Sbjct: 204 PLNAVDER 211
>XP_005246487
          Length = 471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLQAVDQR 8
           PL AVD+R
Sbjct: 204 PLNAVDER 211
>NP_036466
          Length = 2058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QAVDQRD 9
           QAVD RD
Sbjct: 393 QAVDSRD 399
>NP_003205
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLQAVDQR 8
           PL+AVD R
Sbjct: 262 PLEAVDVR 269
>NP_060082
          Length = 707

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLQAVDQRD 9
           P+QA  Q+D
Sbjct: 389 PMQACQQKD 397
>XP_006719555
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLQAVDQRD 9
           P+QA  Q+D
Sbjct: 151 PMQACQQKD 159
>XP_005253638
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLQAVDQRD 9
           P+QA  Q+D
Sbjct: 151 PMQACQQKD 159
>XP_006719554
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLQAVDQRD 9
           P+QA  Q+D
Sbjct: 312 PMQACQQKD 320
>XP_006714538
          Length = 2035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QAVDQRD 9
           QAVD RD
Sbjct: 393 QAVDSRD 399
>NP_001153115
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>NP_060819
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>NP_001159579
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  PLQAVDQRD 9
          P Q VDQ D
Sbjct: 64 PAQYVDQTD 72
>NP_005509
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  PLQAVDQRD 9
          P Q VDQ D
Sbjct: 64 PAQYVDQTD 72
>NP_067636
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVDQRD 9
           LQA DQ+D
Sbjct: 93  LQANDQKD 100
>XP_005255016
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>XP_005255015
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>XP_005255014
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>XP_006720666
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>XP_006720665
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>XP_005255012
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLQAVDQR 8
           P+Q++DQ+
Sbjct: 249 PIQSLDQK 256
>NP_000408
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PLQAVDQ 7
           P+Q VDQ
Sbjct: 112 PMQPVDQ 118
>NP_005434
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PLQAVDQRD 9
           PL   +QRD
Sbjct: 161 PLHVCEQRD 169
>NP_001276968
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PLQAVDQ 7
            PL+A+DQ
Sbjct: 1237 PLRALDQ 1243
>NP_001276969
          Length = 1443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PLQAVDQ 7
            PL+A+DQ
Sbjct: 1237 PLRALDQ 1243
>NP_001276994
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLQAVDQ 7
           PL+A+DQ
Sbjct: 640 PLRALDQ 646
>NP_001122401
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PLQAVDQ 7
            PL+A+DQ
Sbjct: 1249 PLRALDQ 1255
>NP_002933
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PLQAVDQ 7
            PL+A+DQ
Sbjct: 1233 PLRALDQ 1239
>NP_001001974
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>NP_067635
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>NP_001182537
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>NP_006835
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQAVDQ 7
           LQAVDQ
Sbjct: 160 LQAVDQ 165
>NP_006368
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLQAVDQRD 9
           P  AVD RD
Sbjct: 180 PDSAVDDRD 188
>NP_001073890
          Length = 1703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLQAVDQRD 9
           P  AVD RD
Sbjct: 190 PDSAVDDRD 198
>XP_006722755
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLQAVDQRD 9
           P  AVD RD
Sbjct: 190 PDSAVDDRD 198
>XP_005259774
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQAVDQ 7
           LQAVDQ
Sbjct: 160 LQAVDQ 165
>XP_005270078
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_006717998
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270077
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270076
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270075
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270074
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270073
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQAVDQRD 9
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005252503
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PLQAVDQ 7
           P+Q VDQ
Sbjct: 112 PMQPVDQ 118
>XP_006716779
          Length = 2399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLQAVDQRD 9
           P  AVD RD
Sbjct: 192 PDSAVDDRD 200
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.134    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 491,003
Number of extensions: 837
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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