Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              21     229
XP_005262424                                                           21     229
NP_001182741                                                           19     869
NP_689879                                                              19     869
NP_001182740                                                           19     869
XP_006711815                                                           19     869
NP_001137378                                                           18    1935
NP_006691                                                              18    1935
NP_056065                                                              18    1935
NP_001003800                                                           18    1935
NP_115518                                                              17    2528
XP_006722394                                                           17    2528
XP_005258167                                                           17    2528
XP_006722393                                                           17    2528
XP_006722392                                                           17    2528
XP_006722391                                                           17    2528
XP_006722390                                                           17    2528
XP_005258166                                                           17    2528
XP_006722389                                                           17    2528
XP_005258165                                                           17    2528
XP_005258164                                                           17    2528
NP_006232                                                              17    4312
NP_005641                                                              17    4312
XP_006725844                                                           17    4312
XP_005277012                                                           17    4312
XP_006724377                                                           17    4312
XP_006724376                                                           17    4312
XP_005261779                                                           17    4312
XP_006713746                                                           17    4312
XP_006713745                                                           17    4312
NP_001004747                                                           17    4312
NP_002684                                                              16    5631
NP_001119603                                                           16    5631
NP_001091977                                                           16    5631
NP_001027464                                                           16    5631
NP_003448                                                              16    5631
NP_076998                                                              16    5631
NP_072174                                                              16    5631
XP_005258087                                                           16    5631
XP_005258086                                                           16    5631
XP_005258085                                                           16    5631
XP_005264077                                                           16    5631
XP_005264076                                                           16    5631
XP_006712785                                                           16    5631
XP_005246883                                                           16    5631
XP_005246882                                                           16    5631
XP_006712784                                                           16    5631
NP_001034965                                                           16    7355
NP_001273654                                                           16    7355
NP_065917                                                              16    7355
XP_005258659                                                           16    7355
XP_005258657                                                           16    7355
XP_005258656                                                           16    7355
XP_005258654                                                           16    7355
NP_954983                                                              15    9605
XP_006726614                                                           15    9605
XP_006720044                                                           15    9605
XP_006719872                                                           15    9605
XP_006719871                                                           15    9605
XP_006719870                                                           15    9605
XP_006710033                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLNNKTATT 9
           PL+NKTATT
Sbjct: 896 PLDNKTATT 904
>XP_005262424
          Length = 2875

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLNNKTATT 9
           PL+NKTATT
Sbjct: 691 PLDNKTATT 699
>NP_001182741
          Length = 328

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   PLNNKTAT 8
           PL+NKTAT
Sbjct: 310 PLSNKTAT 317
>NP_689879
          Length = 536

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   PLNNKTAT 8
           PL+NKTAT
Sbjct: 518 PLSNKTAT 525
>NP_001182740
          Length = 474

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   PLNNKTAT 8
           PL+NKTAT
Sbjct: 456 PLSNKTAT 463
>XP_006711815
          Length = 536

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   PLNNKTAT 8
           PL+NKTAT
Sbjct: 518 PLSNKTAT 525
>NP_001137378
          Length = 582

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLNNKTAT 8
           P+NN TAT
Sbjct: 454 PINNMTAT 461
>NP_006691
          Length = 582

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PLNNKTAT 8
           P+NN TAT
Sbjct: 454 PINNMTAT 461
>NP_056065
          Length = 824

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   PLNNKTAT 8
           PL+NKT+T
Sbjct: 312 PLDNKTST 319
>NP_001003800
          Length = 855

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   PLNNKTAT 8
           PL+NKT+T
Sbjct: 312 PLDNKTST 319
>NP_115518
          Length = 2537

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1972 INNKTAT 1978
>XP_006722394
          Length = 1845

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1279 INNKTAT 1285
>XP_005258167
          Length = 1856

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1290 INNKTAT 1296
>XP_006722393
          Length = 2199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1633 INNKTAT 1639
>XP_006722392
          Length = 2444

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1878 INNKTAT 1884
>XP_006722391
          Length = 2448

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1882 INNKTAT 1888
>XP_006722390
          Length = 2467

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1902 INNKTAT 1908
>XP_005258166
          Length = 2468

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1902 INNKTAT 1908
>XP_006722389
          Length = 2506

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1972 INNKTAT 1978
>XP_005258165
          Length = 2534

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1968 INNKTAT 1974
>XP_005258164
          Length = 2538

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LNNKTAT 8
            +NNKTAT
Sbjct: 1972 INNKTAT 1978
>NP_006232
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LNNKTATT 9
          L NKT+TT
Sbjct: 15 LKNKTSTT 22
>NP_005641
          Length = 1960

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PLNNKTA 7
            PL NKTA
Sbjct: 1942 PLQNKTA 1948
>XP_006725844
          Length = 1960

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PLNNKTA 7
            PL NKTA
Sbjct: 1942 PLQNKTA 1948
>XP_005277012
          Length = 1960

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PLNNKTA 7
            PL NKTA
Sbjct: 1942 PLQNKTA 1948
>XP_006724377
          Length = 1960

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PLNNKTA 7
            PL NKTA
Sbjct: 1942 PLQNKTA 1948
>XP_006724376
          Length = 1960

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PLNNKTA 7
            PL NKTA
Sbjct: 1942 PLQNKTA 1948
>XP_005261779
          Length = 1960

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    PLNNKTA 7
            PL NKTA
Sbjct: 1942 PLQNKTA 1948
>XP_006713746
          Length = 108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LNNKTATT 9
          L NKT+TT
Sbjct: 15 LKNKTSTT 22
>XP_006713745
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LNNKTATT 9
          L NKT+TT
Sbjct: 15 LKNKTSTT 22
>NP_001004747
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  PLNNKTATT 9
          PL NKT  T
Sbjct: 32 PLKNKTEVT 40
>NP_002684
          Length = 1239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LNNKTATT 9
           L++KTATT
Sbjct: 931 LHSKTATT 938
>NP_001119603
          Length = 1239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LNNKTATT 9
           L++KTATT
Sbjct: 931 LHSKTATT 938
>NP_001091977
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLNNKTATT 9
           PLN+  ATT
Sbjct: 322 PLNSTPATT 330
>NP_001027464
          Length = 463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLNNKTATT 9
           PLN+  ATT
Sbjct: 291 PLNSTPATT 299
>NP_003448
          Length = 478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLNNKTATT 9
           PLN+  ATT
Sbjct: 306 PLNSTPATT 314
>NP_076998
          Length = 232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PLNNKT 6
           P+NNKT
Sbjct: 159 PVNNKT 164
>NP_072174
          Length = 1735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LNNKTATT 9
            L+NK ATT
Sbjct: 1259 LHNKVATT 1266
>XP_005258087
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLNNKTATT 9
           PLN+  ATT
Sbjct: 294 PLNSTPATT 302
>XP_005258086
          Length = 481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLNNKTATT 9
           PLN+  ATT
Sbjct: 309 PLNSTPATT 317
>XP_005258085
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PLNNKTATT 9
           PLN+  ATT
Sbjct: 325 PLNSTPATT 333
>XP_005264077
          Length = 270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PLNNKT 6
           P+NNKT
Sbjct: 197 PVNNKT 202
>XP_005264076
          Length = 270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PLNNKT 6
           P+NNKT
Sbjct: 197 PVNNKT 202
>XP_006712785
          Length = 1352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LNNKTATT 9
           L+NK ATT
Sbjct: 876 LHNKVATT 883
>XP_005246883
          Length = 1352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LNNKTATT 9
           L+NK ATT
Sbjct: 876 LHNKVATT 883
>XP_005246882
          Length = 1518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LNNKTATT 9
            L+NK ATT
Sbjct: 1042 LHNKVATT 1049
>XP_006712784
          Length = 1784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LNNKTATT 9
            L+NK ATT
Sbjct: 1308 LHNKVATT 1315
>NP_001034965
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLNNKTATT 9
           PL  KTA T
Sbjct: 260 PLGQKTART 268
>NP_001273654
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   NNKTATT 9
           NNK ATT
Sbjct: 408 NNKGATT 414
>NP_065917
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   NNKTATT 9
           NNK ATT
Sbjct: 469 NNKGATT 475
>XP_005258659
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLNNKTATT 9
           PL  KTA T
Sbjct: 132 PLGQKTART 140
>XP_005258657
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLNNKTATT 9
           PL  KTA T
Sbjct: 180 PLGQKTART 188
>XP_005258656
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLNNKTATT 9
           PL  KTA T
Sbjct: 195 PLGQKTART 203
>XP_005258654
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PLNNKTATT 9
           PL  KTA T
Sbjct: 260 PLGQKTART 268
>NP_954983
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   PLNNKT 6
           P NNKT
Sbjct: 180 PYNNKT 185
>XP_006726614
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PLNNKTATT 9
          PL+  TATT
Sbjct: 76 PLSISTATT 84
>XP_006720044
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PLNNKTATT 9
          PL+  TATT
Sbjct: 76 PLSISTATT 84
>XP_006719872
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   PLNNKT 6
           P NNKT
Sbjct: 180 PYNNKT 185
>XP_006719871
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   PLNNKT 6
           P NNKT
Sbjct: 180 PYNNKT 185
>XP_006719870
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   PLNNKT 6
           P NNKT
Sbjct: 180 PYNNKT 185
>XP_006710033
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PLNNKTATT 9
          PL+  TATT
Sbjct: 76 PLSISTATT 84
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.109    0.295 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 560,591
Number of extensions: 806
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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