Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     390
NP_001263689                                                           20     390
NP_001119584                                                           20     390
NP_001119586                                                           20     390
NP_001263625                                                           20     390
NP_001119590                                                           20     390
NP_001263690                                                           20     390
NP_001119585                                                           20     390
NP_001263624                                                           20     390
NP_001119588                                                           20     390
NP_001119587                                                           20     390
NP_001119589                                                           20     390
NP_001263627                                                           20     390
NP_001263628                                                           20     390
NP_001263626                                                           20     390
NP_001191121                                                           18    1935
NP_001119713                                                           18    1935
NP_001191117                                                           18    1935
NP_001119712                                                           18    1935
NP_001119714                                                           18    1935
NP_005418                                                              18    1935
NP_001191116                                                           18    1935
NP_001191115                                                           18    1935
NP_001191119                                                           18    1935
NP_001191113                                                           18    1935
NP_001191118                                                           18    1935
NP_001191120                                                           18    1935
NP_001191114                                                           18    1935
NP_001108451                                                           17    2528
NP_001108454                                                           17    2528
NP_003713                                                              17    2528
NP_001108450                                                           17    2528
NP_001108452                                                           17    2528
NP_001108453                                                           17    2528
XP_005247903                                                           17    2528
XP_005247901                                                           17    2528
XP_005247900                                                           17    2528
NP_001156367                                                           17    3301
NP_001156366                                                           17    3301
NP_001156365                                                           17    3301
XP_005245685                                                           17    3301
NP_055471                                                              17    3301
NP_055816                                                              17    4312
NP_000224                                                              16    5631
NP_000360                                                              16    5631
XP_005268094                                                           16    5631
XP_005264366                                                           16    5631
XP_006712078                                                           16    5631
NP_001240658                                                           16    7355
NP_001240657                                                           16    7355
NP_001240656                                                           16    7355
NP_001240659                                                           16    7355
NP_001240662                                                           16    7355
NP_001240661                                                           16    7355
NP_067647                                                              16    7355
NP_038475                                                              16    7355
NP_115960                                                              16    7355
NP_898898                                                              16    7355
NP_001257981                                                           16    7355
NP_001276087                                                           16    7355
XP_005259943                                                           16    7355
XP_005259942                                                           16    7355
XP_005259941                                                           16    7355
XP_005262777                                                           16    7355
XP_005262774                                                           16    7355
NP_001276088                                                           16    7355
NP_005281                                                              15    9605
NP_079235                                                              15    9605
NP_001159530                                                           15    9605
NP_001258949                                                           15    9605
NP_570718                                                              15    9605
XP_006720385                                                           15    9605
XP_005268275                                                           15    9605
XP_006719671                                                           15    9605
XP_006719670                                                           15    9605
NP_003649                                                              15    9605
>NP_000537
          Length = 393

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 250 PILTIITLE 258
>NP_001263689
          Length = 354

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 211 PILTIITLE 219
>NP_001119584
          Length = 393

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 250 PILTIITLE 258
>NP_001119586
          Length = 341

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 250 PILTIITLE 258
>NP_001263625
          Length = 302

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 211 PILTIITLE 219
>NP_001119590
          Length = 354

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 211 PILTIITLE 219
>NP_001263690
          Length = 354

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 211 PILTIITLE 219
>NP_001119585
          Length = 346

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 250 PILTIITLE 258
>NP_001263624
          Length = 307

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 211 PILTIITLE 219
>NP_001119588
          Length = 209

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 118 PILTIITLE 126
>NP_001119587
          Length = 261

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 118 PILTIITLE 126
>NP_001119589
          Length = 214

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PLLTIITLE 9
           P+LTIITLE
Sbjct: 118 PILTIITLE 126
>NP_001263627
          Length = 182

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  PLLTIITLE 9
          P+LTIITLE
Sbjct: 91 PILTIITLE 99
>NP_001263628
          Length = 187

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  PLLTIITLE 9
          P+LTIITLE
Sbjct: 91 PILTIITLE 99
>NP_001263626
          Length = 234

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  PLLTIITLE 9
          P+LTIITLE
Sbjct: 91 PILTIITLE 99
>NP_001191121
          Length = 565

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 199 PILIIITLE 207
>NP_001119713
          Length = 450

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 221 PILIIITLE 229
>NP_001191117
          Length = 540

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 270 PILIIITLE 278
>NP_001119712
          Length = 587

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 221 PILIIITLE 229
>NP_001119714
          Length = 426

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 221 PILIIITLE 229
>NP_005418
          Length = 636

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 270 PILIIITLE 278
>NP_001191116
          Length = 555

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 270 PILIIITLE 278
>NP_001191115
          Length = 403

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 270 PILIIITLE 278
>NP_001191119
          Length = 506

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 221 PILIIITLE 229
>NP_001191113
          Length = 499

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 270 PILIIITLE 278
>NP_001191118
          Length = 354

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 221 PILIIITLE 229
>NP_001191120
          Length = 491

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 221 PILIIITLE 229
>NP_001191114
          Length = 475

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L IITLE
Sbjct: 270 PILIIITLE 278
>NP_001108451
          Length = 487

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 320 PILIIVTLE 328
>NP_001108454
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 226 PILIIVTLE 234
>NP_003713
          Length = 680

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 320 PILIIVTLE 328
>NP_001108450
          Length = 555

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 320 PILIIVTLE 328
>NP_001108452
          Length = 586

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 226 PILIIVTLE 234
>NP_001108453
          Length = 461

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 226 PILIIVTLE 234
>XP_005247903
          Length = 483

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 320 PILIIVTLE 328
>XP_005247901
          Length = 663

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 303 PILIIVTLE 311
>XP_005247900
          Length = 676

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           P+L I+TLE
Sbjct: 320 PILIIVTLE 328
>NP_001156367
          Length = 99

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  PLLTIITL 8
          PLL IITL
Sbjct: 36 PLLVIITL 43
>NP_001156366
          Length = 99

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  PLLTIITL 8
          PLL IITL
Sbjct: 36 PLLVIITL 43
>NP_001156365
          Length = 99

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  PLLTIITL 8
          PLL IITL
Sbjct: 36 PLLVIITL 43
>XP_005245685
          Length = 99

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  PLLTIITL 8
          PLL IITL
Sbjct: 36 PLLVIITL 43
>NP_055471
          Length = 99

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  PLLTIITL 8
          PLL IITL
Sbjct: 36 PLLVIITL 43
>NP_055816
          Length = 3664

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    PLLTIITLE 9
            P +T++TLE
Sbjct: 1640 PSVTVVTLE 1648
>NP_000224
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTIITLE 9
           LT+ITLE
Sbjct: 457 LTVITLE 463
>NP_000360
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTIITLE 9
           LT+ITLE
Sbjct: 512 LTVITLE 518
>XP_005268094
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTIITLE 9
           LT+ITLE
Sbjct: 512 LTVITLE 518
>XP_005264366
          Length = 380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTIITLE 9
           LT+ITLE
Sbjct: 138 LTVITLE 144
>XP_006712078
          Length = 389

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTIITLE 9
           LT+ITLE
Sbjct: 147 LTVITLE 153
>NP_001240658
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 454 LLTFLTLE 461
>NP_001240657
          Length = 724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 469 LLTFLTLE 476
>NP_001240656
          Length = 784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 529 LLTFLTLE 536
>NP_001240659
          Length = 626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 371 LLTFLTLE 378
>NP_001240662
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 346 LLTFLTLE 353
>NP_001240661
          Length = 625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 370 LLTFLTLE 377
>NP_067647
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 502 LLTFLTLE 509
>NP_038475
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 534 PVLTVIT 540
>NP_115960
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 354 PVLTVIT 360
>NP_898898
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           PL++I+T E
Sbjct: 154 PLISIVTKE 162
>NP_001257981
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 476 PVLTVIT 482
>NP_001276087
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 302 PVLTVIT 308
>XP_005259943
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 262 PVLTVIT 268
>XP_005259942
          Length = 834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 545 PVLTVIT 551
>XP_005259941
          Length = 892

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 603 PVLTVIT 609
>XP_005262777
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           PL++I+T E
Sbjct: 154 PLISIVTKE 162
>XP_005262774
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           PL++I+T E
Sbjct: 154 PLISIVTKE 162
>NP_001276088
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           P+LT+IT
Sbjct: 228 PVLTVIT 234
>NP_005281
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PLLTIIT 7
           PLL+I+T
Sbjct: 207 PLLSIVT 213
>NP_079235
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           PL+ ++TL+
Sbjct: 367 PLVVVLTLQ 375
>NP_001159530
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 488 LLTYLTLE 495
>NP_001258949
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PLLTII 6
           PLLTII
Sbjct: 363 PLLTII 368
>NP_570718
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTIITLE 9
           LLT +TLE
Sbjct: 512 LLTYLTLE 519
>XP_006720385
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    PLLTII 6
            PLLTII
Sbjct: 1409 PLLTII 1414
>XP_005268275
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    PLLTII 6
            PLLTII
Sbjct: 1410 PLLTII 1415
>XP_006719671
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           PL+ ++TL+
Sbjct: 367 PLVVVLTLQ 375
>XP_006719670
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PLLTIITLE 9
           PL+ ++TL+
Sbjct: 172 PLVVVLTLQ 180
>NP_003649
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PLLTIIT 7
          PLL++IT
Sbjct: 71 PLLSVIT 77
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.150    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 433,248
Number of extensions: 899
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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