Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_000024                                                              16    5631
NP_001136095                                                           16    7355
NP_001136094                                                           16    7355
NP_115873                                                              16    7355
NP_078934                                                              15    9605
NP_665736                                                              15    9605
NP_005255                                                              15    9605
NP_001138925                                                           15    9605
NP_653274                                                              15    9605
NP_001008270                                                           15    9605
NP_002579                                                              15    9605
NP_115778                                                              15    9605
XP_005269753                                                           15    9605
NP_005155                                                              15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1303 PLLRIVITS 1311
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1303 PLLRIVITS 1311
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1313 PLLRIVITS 1321
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1313 PLLRIVITS 1321
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1313 PLLRIVITS 1321
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1303 PLLRIVITS 1311
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1313 PLLRIVITS 1321
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1313 PLLRIVITS 1321
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1300 PLLRIVITS 1308
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1303 PLLRIVITS 1311
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PLLQIVITS 9
            PLL+IVITS
Sbjct: 1313 PLLRIVITS 1321
>NP_000024
          Length = 745

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PLLQIVITS 9
           PLL + +TS
Sbjct: 218 PLLDVAVTS 226
>NP_001136095
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PLLQIVIT 8
           P LQ+V+T
Sbjct: 257 PKLQVVVT 264
>NP_001136094
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PLLQIVIT 8
           P LQ+V+T
Sbjct: 218 PKLQVVVT 225
>NP_115873
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PLLQIVIT 8
           P LQ+V+T
Sbjct: 257 PKLQVVVT 264
>NP_078934
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   PLLQIV 6
           PLLQIV
Sbjct: 394 PLLQIV 399
>NP_665736
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           PLL +V+T+
Sbjct: 441 PLLVLVVTA 449
>NP_005255
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           PLL +V+T+
Sbjct: 446 PLLVLVVTA 454
>NP_001138925
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           PLL +V+T+
Sbjct: 441 PLLVLVVTA 449
>NP_653274
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PLLQIVIT 8
           P+L+++IT
Sbjct: 112 PILRLIIT 119
>NP_001008270
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PLLQIVITS 9
          PLL +++TS
Sbjct: 9  PLLLLLVTS 17
>NP_002579
          Length = 934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           P LQ+V+T+
Sbjct: 208 PSLQLVLTA 216
>NP_115778
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           P LQ+V+T+
Sbjct: 208 PSLQLVLTA 216
>XP_005269753
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           PLL +V+T+
Sbjct: 446 PLLVLVVTA 454
>NP_005155
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PLLQIVITS 9
           P+L +++TS
Sbjct: 231 PILDVMLTS 239
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.144    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 371,129
Number of extensions: 600
Number of successful extensions: 25
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package