Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           21     175
NP_036462                                                              21     175
NP_001243397                                                           21     175
XP_005269721                                                           21     175
NP_945173                                                              16    5631
NP_689717                                                              16    5631
NP_001364                                                              16    5631
NP_001077059                                                           16    5631
NP_037458                                                              16    5631
XP_006723834                                                           16    5631
XP_005260448                                                           16    5631
XP_005260446                                                           16    5631
XP_006723612                                                           16    5631
XP_006722508                                                           16    5631
XP_006712099                                                           16    5631
XP_005264439                                                           16    5631
XP_005264438                                                           16    5631
XP_006711798                                                           16    5631
NP_060197                                                              16    5631
NP_001182185                                                           16    7355
NP_848618                                                              16    7355
XP_005259432                                                           16    7355
NP_001006659                                                           15    9605
NP_001868                                                              15    9605
NP_490597                                                              15    9605
NP_055114                                                              15    9605
NP_061869                                                              15    9605
NP_001136112                                                           15    9605
NP_665682                                                              15    9605
NP_001230937                                                           15    9605
NP_958357                                                              15    9605
NP_001188410                                                           15    9605
NP_115912                                                              15    9605
NP_001188411                                                           15    9605
NP_004827                                                              15    9605
NP_001188409                                                           15    9605
NP_443179                                                              15    9605
NP_997254                                                              15    9605
NP_001660                                                              15    9605
NP_115622                                                              15    9605
XP_005274573                                                           15    9605
XP_005274572                                                           15    9605
XP_005274571                                                           15    9605
XP_006722063                                                           15    9605
XP_006722062                                                           15    9605
XP_006722061                                                           15    9605
XP_006722060                                                           15    9605
XP_005257605                                                           15    9605
XP_005257604                                                           15    9605
XP_006722059                                                           15    9605
XP_005252508                                                           15    9605
XP_006717511                                                           15    9605
XP_005252507                                                           15    9605
XP_005247083                                                           15    9605
XP_005247080                                                           15    9605
XP_005247079                                                           15    9605
XP_006712295                                                           15    9605
XP_006712294                                                           15    9605
XP_005264706                                                           15    9605
XP_005271318                                                           15    9605
XP_005271317                                                           15    9605
XP_005271314                                                           15    9605
NP_955353                                                              15    9605
NP_942141                                                              15    9605
>NP_001243398
          Length = 1781

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PKTSNANIG 9
            P+TSNANIG
Sbjct: 1493 PETSNANIG 1501
>NP_036462
          Length = 2073

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PKTSNANIG 9
            P+TSNANIG
Sbjct: 1785 PETSNANIG 1793
>NP_001243397
          Length = 1890

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PKTSNANIG 9
            P+TSNANIG
Sbjct: 1602 PETSNANIG 1610
>XP_005269721
          Length = 2073

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    PKTSNANIG 9
            P+TSNANIG
Sbjct: 1785 PETSNANIG 1793
>NP_945173
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PKTSNANIG 9
          P T N N+G
Sbjct: 78 PPTQNMNLG 86
>NP_689717
          Length = 205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PKTSNANI 8
          P TSN NI
Sbjct: 59 PDTSNLNI 66
>NP_001364
          Length = 4515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PKTSNANI 8
            PKT+ AN+
Sbjct: 4127 PKTTTANL 4134
>NP_001077059
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK + AN+G
Sbjct: 186 PKIATANLG 194
>NP_037458
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KTSNANI 8
           KT NANI
Sbjct: 107 KTKNANI 113
>XP_006723834
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PKTSNANIG 9
          P T N N+G
Sbjct: 56 PPTQNMNLG 64
>XP_005260448
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PKTSNANIG 9
          P T N N+G
Sbjct: 56 PPTQNMNLG 64
>XP_005260446
          Length = 416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PKTSNANIG 9
          P T N N+G
Sbjct: 78 PPTQNMNLG 86
>XP_006723612
          Length = 207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PKTSNANI 8
          P TSN NI
Sbjct: 61 PDTSNLNI 68
>XP_006722508
          Length = 609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KTSNANI 8
           KT NANI
Sbjct: 107 KTKNANI 113
>XP_006712099
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK + AN+G
Sbjct: 186 PKIATANLG 194
>XP_005264439
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK + AN+G
Sbjct: 231 PKIATANLG 239
>XP_005264438
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK + AN+G
Sbjct: 231 PKIATANLG 239
>XP_006711798
          Length = 4586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    PKTSNANI 8
            PKT+ AN+
Sbjct: 4198 PKTTTANL 4205
>NP_060197
          Length = 689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK + AN+G
Sbjct: 231 PKIATANLG 239
>NP_001182185
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PKTSNAN 7
           P+TSN N
Sbjct: 198 PETSNTN 204
>NP_848618
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PKTSNANIG 9
          P T N+N G
Sbjct: 58 PPTENSNTG 66
>XP_005259432
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PKTSNANIG 9
          P T N+N G
Sbjct: 58 PPTENSNTG 66
>NP_001006659
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   PKTSNAN 7
           PKT N N
Sbjct: 914 PKTPNGN 920
>NP_001868
          Length = 1033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   PKTSNAN 7
           PKT N N
Sbjct: 855 PKTPNGN 861
>NP_490597
          Length = 1362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  PKTSNAN 7
          P+TSN N
Sbjct: 48 PETSNPN 54
>NP_055114
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  PKTSNAN 7
          P+TSN N
Sbjct: 48 PETSNPN 54
>NP_061869
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 256 PATGNSNSG 264
>NP_001136112
          Length = 1726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 256 PATGNSNSG 264
>NP_665682
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 568 PDTSNINL 575
>NP_001230937
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK +NA +G
Sbjct: 401 PKLTNALVG 409
>NP_958357
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTSNANIG 9
           KTSN N G
Sbjct: 127 KTSNMNKG 134
>NP_001188410
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 533 PDTSNINL 540
>NP_115912
          Length = 934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 564 PDTSNINL 571
>NP_001188411
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 528 PDTSNINL 535
>NP_004827
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PKT+  +IG
Sbjct: 822 PKTNRLHIG 830
>NP_001188409
          Length = 959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 589 PDTSNINL 596
>NP_443179
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           PK  NAN+
Sbjct: 546 PKKPNANL 553
>NP_997254
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PKTSNA 6
           PKT+NA
Sbjct: 583 PKTNNA 588
>NP_001660
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PKTSNA 6
          PKT+NA
Sbjct: 33 PKTANA 38
>NP_115622
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SNANIG 9
           SNAN+G
Sbjct: 420 SNANLG 425
>XP_005274573
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PKTSNA 6
          PKT+NA
Sbjct: 33 PKTANA 38
>XP_005274572
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PKTSNA 6
          PKT+NA
Sbjct: 33 PKTANA 38
>XP_005274571
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PKTSNA 6
          PKT+NA
Sbjct: 33 PKTANA 38
>XP_006722063
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_006722062
          Length = 1866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_006722061
          Length = 1913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_006722060
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_005257605
          Length = 1926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_005257604
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_006722059
          Length = 1965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PKTSNANIG 9
           P T N+N G
Sbjct: 492 PATGNSNSG 500
>XP_005252508
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PKTSNA 6
           PKT+NA
Sbjct: 583 PKTNNA 588
>XP_006717511
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PKTSNA 6
           PKT+NA
Sbjct: 583 PKTNNA 588
>XP_005252507
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PKTSNA 6
           PKT+NA
Sbjct: 583 PKTNNA 588
>XP_005247083
          Length = 1699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK +NA +G
Sbjct: 401 PKLTNALVG 409
>XP_005247080
          Length = 1799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK +NA +G
Sbjct: 401 PKLTNALVG 409
>XP_005247079
          Length = 1800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PK +NA +G
Sbjct: 401 PKLTNALVG 409
>XP_006712295
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 553 PDTSNINL 560
>XP_006712294
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   PKTSNANI 8
           P TSN N+
Sbjct: 558 PDTSNINL 565
>XP_005264706
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKTSNANIG 9
           PKT+  +IG
Sbjct: 594 PKTNRLHIG 602
>XP_005271318
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTSNANIG 9
           KTSN N G
Sbjct: 127 KTSNMNKG 134
>XP_005271317
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTSNANIG 9
           KTSN N G
Sbjct: 127 KTSNMNKG 134
>XP_005271314
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTSNANIG 9
           KTSN N G
Sbjct: 127 KTSNMNKG 134
>NP_955353
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PKTSNAN 7
           P+TSN N
Sbjct: 327 PQTSNKN 333
>NP_942141
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PKTSNAN 7
           P+TSN N
Sbjct: 305 PQTSNKN 311
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.118    0.326 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,263
Number of extensions: 1037
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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