Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     299
XP_005262424                                                           20     299
NP_054868                                                              17    3301
XP_005250342                                                           17    3301
NP_001239155                                                           16    5631
NP_006613                                                              16    5631
NP_061181                                                              16    5631
NP_038477                                                              16    5631
XP_006719271                                                           16    5631
XP_005268661                                                           16    5631
XP_005268660                                                           16    5631
XP_005268659                                                           16    5631
XP_005268657                                                           16    5631
XP_006719270                                                           16    5631
XP_005268656                                                           16    5631
XP_005268654                                                           16    5631
XP_005268653                                                           16    5631
NP_001138295                                                           16    7355
NP_005839                                                              16    7355
NP_001269618                                                           16    7355
NP_055524                                                              16    7355
NP_076982                                                              16    7355
NP_001269619                                                           16    7355
NP_001269617                                                           16    7355
XP_006726471                                                           16    7355
XP_005254179                                                           16    7355
XP_005254178                                                           16    7355
XP_006720435                                                           16    7355
XP_005254177                                                           16    7355
XP_006720434                                                           16    7355
XP_005254176                                                           16    7355
XP_006717345                                                           16    7355
XP_005252255                                                           16    7355
XP_005252253                                                           16    7355
XP_005252252                                                           16    7355
XP_005252250                                                           16    7355
XP_006710212                                                           16    7355
NP_067653                                                              15    9605
NP_001124468                                                           15    9605
NP_000850                                                              15    9605
NP_001185708                                                           15    9605
NP_003582                                                              15    9605
NP_060720                                                              15    9605
NP_694533                                                              15    9605
NP_001276091                                                           15    9605
NP_653292                                                              15    9605
NP_001185707                                                           15    9605
NP_001185706                                                           15    9605
XP_006721364                                                           15    9605
XP_005273625                                                           15    9605
XP_006716420                                                           15    9605
XP_006716419                                                           15    9605
XP_003403748                                                           15    9605
NP_001138631                                                           15    9605
NP_001070706                                                           15    9605
NP_619635                                                              15    9605
NP_001276092                                                           15    9605
NP_115645                                                              15    9605
>NP_722576
          Length = 3080

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PKFKLTTLL 9
           P+FKLTTLL
Sbjct: 752 PEFKLTTLL 760
>XP_005262424
          Length = 2875

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PKFKLTTLL 9
           P+FKLTTLL
Sbjct: 547 PEFKLTTLL 555
>NP_054868
          Length = 747

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KFKLTTLL 9
           K KLTTLL
Sbjct: 736 KIKLTTLL 743
>XP_005250342
          Length = 773

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KFKLTTLL 9
           K KLTTLL
Sbjct: 762 KIKLTTLL 769
>NP_001239155
          Length = 671

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FKLTTLL 9
           F+LTTLL
Sbjct: 641 FRLTTLL 647
>NP_006613
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FKLTTLL 9
           F+LTTLL
Sbjct: 655 FRLTTLL 661
>NP_061181
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           P F+ TTLL
Sbjct: 311 PHFRWTTLL 319
>NP_038477
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 677 PKVKITELL 685
>XP_006719271
          Length = 1555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 696 PKVKITELL 704
>XP_005268661
          Length = 1657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 429 PKVKITELL 437
>XP_005268660
          Length = 1875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 647 PKVKITELL 655
>XP_005268659
          Length = 1894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 666 PKVKITELL 674
>XP_005268657
          Length = 1903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 675 PKVKITELL 683
>XP_006719270
          Length = 1903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 675 PKVKITELL 683
>XP_005268656
          Length = 1903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 675 PKVKITELL 683
>XP_005268654
          Length = 1923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 696 PKVKITELL 704
>XP_005268653
          Length = 1924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK K+T LL
Sbjct: 696 PKVKITELL 704
>NP_001138295
          Length = 1906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1347 PSFNLDTLL 1355
>NP_005839
          Length = 1863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1304 PSFNLDTLL 1312
>NP_001269618
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 141 PEFEFTTL 148
>NP_055524
          Length = 3546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    PKFKLTTLL 9
            P FKL T+L
Sbjct: 2602 PFFKLLTML 2610
>NP_076982
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 214 PEFEFTTL 221
>NP_001269619
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 146 PEFEFTTL 153
>NP_001269617
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 213 PEFEFTTL 220
>XP_006726471
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KFKLTTLL 9
          +FK++TLL
Sbjct: 15 RFKISTLL 22
>XP_005254179
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PKFKLTTLL 9
           P F L TLL
Sbjct: 614 PSFNLDTLL 622
>XP_005254178
          Length = 1863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1304 PSFNLDTLL 1312
>XP_006720435
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1348 PSFNLDTLL 1356
>XP_005254177
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1348 PSFNLDTLL 1356
>XP_006720434
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1348 PSFNLDTLL 1356
>XP_005254176
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    PKFKLTTLL 9
            P F L TLL
Sbjct: 1348 PSFNLDTLL 1356
>XP_006717345
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 141 PEFEFTTL 148
>XP_005252255
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 146 PEFEFTTL 153
>XP_005252253
          Length = 815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 214 PEFEFTTL 221
>XP_005252252
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 214 PEFEFTTL 221
>XP_005252250
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+ TTL
Sbjct: 214 PEFEFTTL 221
>XP_006710212
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KFKLTTLL 9
          +FK++TLL
Sbjct: 15 RFKISTLL 22
>NP_067653
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           P++ LTT L
Sbjct: 187 PRYALTTTL 195
>NP_001124468
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           P +KL TL+
Sbjct: 477 PAYKLETLM 485
>NP_000850
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           P +KL TL+
Sbjct: 477 PAYKLETLM 485
>NP_001185708
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KFKLTT 7
           KFK+TT
Sbjct: 663 KFKITT 668
>NP_003582
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KFKLTT 7
           KFK+TT
Sbjct: 650 KFKITT 655
>NP_060720
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KFKLTTLL 9
          KFK TT++
Sbjct: 18 KFKSTTIM 25
>NP_694533
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PKFKLTTLL 9
           P FK  TLL
Sbjct: 343 PTFKACTLL 351
>NP_001276091
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PKFKLTTL 8
           PKF  TTL
Sbjct: 126 PKFVSTTL 133
>NP_653292
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PKFKLTTL 8
           P+F+LT L
Sbjct: 383 PQFRLTLL 390
>NP_001185707
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KFKLTT 7
           KFK+TT
Sbjct: 669 KFKITT 674
>NP_001185706
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KFKLTT 7
           KFK+TT
Sbjct: 650 KFKITT 655
>XP_006721364
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PKFKLTTL 8
           PKF  TTL
Sbjct: 126 PKFVSTTL 133
>XP_005273625
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KFKLTTLL 9
          KFK TT++
Sbjct: 18 KFKSTTIM 25
>XP_006716420
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KFKLTTLL 9
          KFK TT++
Sbjct: 18 KFKSTTIM 25
>XP_006716419
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KFKLTTLL 9
          KFK TT++
Sbjct: 18 KFKSTTIM 25
>XP_003403748
          Length = 997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK ++ TLL
Sbjct: 369 PKLRVVTLL 377
>NP_001138631
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KFKLTTLL 9
          KFK TT++
Sbjct: 18 KFKSTTIM 25
>NP_001070706
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PKFKLTTLL 9
           P FK  TLL
Sbjct: 343 PTFKACTLL 351
>NP_619635
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PKFKLTTLL 9
           PK ++ TLL
Sbjct: 415 PKLRVVTLL 423
>NP_001276092
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PKFKLTTL 8
           PKF  TTL
Sbjct: 126 PKFVSTTL 133
>NP_115645
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PKFKLTTL 8
           PKF  TTL
Sbjct: 126 PKFVSTTL 133
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.144    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 377,055
Number of extensions: 494
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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