Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           19     869
NP_001277143                                                           19     869
NP_001077383                                                           19     869
NP_001320                                                              19     869
NP_073713                                                              19     869
XP_005269629                                                           19     869
XP_005269628                                                           19     869
XP_005269627                                                           19     869
XP_005269626                                                           19     869
XP_006717706                                                           19     869
XP_005269625                                                           19     869
XP_005269624                                                           19     869
XP_006717705                                                           19     869
XP_005269622                                                           19     869
XP_005269621                                                           19     869
XP_006717704                                                           19     869
XP_005269619                                                           19     869
XP_005269618                                                           19     869
NP_001319                                                              18    1935
NP_001012632                                                           18    1935
XP_005272320                                                           18    1935
XP_005272319                                                           18    1935
XP_005272318                                                           18    1935
NP_005041                                                              16    7355
NP_079455                                                              16    7355
NP_665682                                                              16    7355
NP_001188410                                                           16    7355
NP_115912                                                              16    7355
NP_001188411                                                           16    7355
NP_001188409                                                           16    7355
NP_056280                                                              16    7355
NP_001239085                                                           16    7355
NP_115618                                                              16    7355
XP_005268010                                                           16    7355
XP_005268011                                                           16    7355
XP_005268009                                                           16    7355
XP_005268008                                                           16    7355
XP_005268003                                                           16    7355
XP_005268006                                                           16    7355
XP_005267999                                                           16    7355
XP_005267997                                                           16    7355
XP_005267998                                                           16    7355
XP_005267996                                                           16    7355
XP_005267995                                                           16    7355
XP_006720286                                                           16    7355
XP_005267993                                                           16    7355
XP_006713726                                                           16    7355
XP_006712295                                                           16    7355
XP_006712294                                                           16    7355
XP_005273222                                                           16    7355
XP_006711450                                                           16    7355
XP_005273221                                                           16    7355
NP_000622                                                              15    9605
NP_006609                                                              15    9605
NP_001164409                                                           15    9605
NP_057452                                                              15    9605
NP_001240318                                                           15    9605
NP_689712                                                              15    9605
NP_001106197                                                           15    9605
NP_653206                                                              15    9605
NP_055820                                                              15    9605
NP_065962                                                              15    9605
NP_001147930                                                           15    9605
NP_003426                                                              15    9605
XP_006722829                                                           15    9605
XP_006720910                                                           15    9605
XP_006720909                                                           15    9605
XP_005267607                                                           15    9605
XP_005268358                                                           15    9605
XP_005268360                                                           15    9605
XP_005250743                                                           15    9605
XP_006716234                                                           15    9605
>NP_001277144
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>NP_001277143
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>NP_001077383
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>NP_001320
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>NP_073713
          Length = 985

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PILKDLAIV 9
           PILKDLA V
Sbjct: 589 PILKDLATV 597
>XP_005269629
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269628
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269627
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269626
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_006717706
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269625
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269624
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_006717705
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269622
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269621
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_006717704
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269619
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>XP_005269618
          Length = 445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKDLA V
Sbjct: 49 PILKDLATV 57
>NP_001319
          Length = 440

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKD+A V
Sbjct: 43 PILKDVATV 51
>NP_001012632
          Length = 429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKD+A V
Sbjct: 32 PILKDVATV 40
>XP_005272320
          Length = 430

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKD+A V
Sbjct: 32 PILKDVATV 40
>XP_005272319
          Length = 430

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKD+A V
Sbjct: 32 PILKDVATV 40
>XP_005272318
          Length = 441

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  PILKDLAIV 9
          PILKD+A V
Sbjct: 43 PILKDVATV 51
>NP_005041
          Length = 606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 402 PLIKDLSL 409
>NP_079455
          Length = 1894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           PIL+D+A
Sbjct: 481 PILRDMA 487
>NP_665682
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 844 PVLKDL 849
>NP_001188410
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 809 PVLKDL 814
>NP_115912
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 840 PVLKDL 845
>NP_001188411
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 804 PVLKDL 809
>NP_001188409
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 865 PVLKDL 870
>NP_056280
          Length = 1508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    PILKDL 6
            P+LKDL
Sbjct: 1020 PVLKDL 1025
>NP_001239085
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    PILKDL 6
            P+LKDL
Sbjct: 1019 PVLKDL 1024
>NP_115618
          Length = 1896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PILKDLAI 8
           PIL+DL +
Sbjct: 485 PILRDLVL 492
>XP_005268010
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 139 PLIKDLSL 146
>XP_005268011
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 139 PLIKDLSL 146
>XP_005268009
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 139 PLIKDLSL 146
>XP_005268008
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 139 PLIKDLSL 146
>XP_005268003
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 243 PLIKDLSL 250
>XP_005268006
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 243 PLIKDLSL 250
>XP_005267999
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 264 PLIKDLSL 271
>XP_005267997
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 264 PLIKDLSL 271
>XP_005267998
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 264 PLIKDLSL 271
>XP_005267996
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 264 PLIKDLSL 271
>XP_005267995
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 402 PLIKDLSL 409
>XP_006720286
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 315 PLIKDLSL 322
>XP_005267993
          Length = 528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   PILKDLAI 8
           P++KDL++
Sbjct: 402 PLIKDLSL 409
>XP_006713726
          Length = 1910

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PILKDLAI 8
           PIL+DL +
Sbjct: 503 PILRDLVL 510
>XP_006712295
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 829 PVLKDL 834
>XP_006712294
          Length = 928

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 834 PVLKDL 839
>XP_005273222
          Length = 1823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           PIL+D+A
Sbjct: 496 PILRDMA 502
>XP_006711450
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           PIL+D+A
Sbjct: 496 PILRDMA 502
>XP_005273221
          Length = 1974

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           PIL+D+A
Sbjct: 496 PILRDMA 502
>NP_000622
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 265 PLLKDL 270
>NP_006609
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PILKDL 6
           P+LKDL
Sbjct: 860 PLLKDL 865
>NP_001164409
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PILKDLAIV 9
           PI+ DLA++
Sbjct: 371 PIMLDLALL 379
>NP_057452
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PILKDLAIV 9
           PI+ DLA++
Sbjct: 425 PIMLDLALL 433
>NP_001240318
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PILKDLAIV 9
           PI+ DLA++
Sbjct: 297 PIMLDLALL 305
>NP_689712
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PILKDL 6
          P+LKDL
Sbjct: 75 PLLKDL 80
>NP_001106197
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           P+L+DLA
Sbjct: 890 PLLQDLA 896
>NP_653206
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PILKDLAI 8
           P+L+DL I
Sbjct: 284 PLLRDLLI 291
>NP_055820
          Length = 1519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           P+L+DLA
Sbjct: 820 PLLQDLA 826
>NP_065962
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           P+L+D+A
Sbjct: 480 PVLRDMA 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    PILKDLAI 8
            P+L+DL +
Sbjct: 1333 PVLRDLEV 1340
>NP_001147930
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PILKDLAI 8
           P+L+DL I
Sbjct: 238 PLLRDLLI 245
>NP_003426
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PILKDL 6
          PILKD+
Sbjct: 57 PILKDI 62
>XP_006722829
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PILKDLAIV 9
           PI+ DLA++
Sbjct: 620 PIMLDLALL 628
>XP_006720910
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PILKDLAI 8
           P+L+DL I
Sbjct: 260 PLLRDLLI 267
>XP_006720909
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PILKDLAI 8
           P+L+DL I
Sbjct: 284 PLLRDLLI 291
>XP_005267607
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           P+L+DLA
Sbjct: 890 PLLQDLA 896
>XP_005268358
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    PILKDL 6
            P+LKDL
Sbjct: 1127 PLLKDL 1132
>XP_005268360
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    PILKDL 6
            P+LKDL
Sbjct: 1127 PLLKDL 1132
>XP_005250743
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           P+L+D+A
Sbjct: 480 PVLRDMA 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    PILKDLAI 8
            P+L+DL +
Sbjct: 1333 PVLRDLEV 1340
>XP_006716234
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   PILKDLA 7
           P+L+D+A
Sbjct: 480 PVLRDMA 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    PILKDLAI 8
            P+L+DL +
Sbjct: 1333 PVLRDLEV 1340
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.155    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 534,828
Number of extensions: 756
Number of successful extensions: 75
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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