Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060421                                                              17    4312
NP_001164554                                                           17    4312
NP_148936                                                              17    4312
NP_001245390                                                           17    4312
NP_006703                                                              17    4312
NP_060221                                                              17    4312
XP_005249990                                                           17    4312
XP_005249989                                                           17    4312
XP_005263761                                                           17    4312
XP_006712688                                                           17    4312
NP_056224                                                              16    5631
NP_001268449                                                           16    5631
NP_877954                                                              16    5631
NP_001268450                                                           16    5631
NP_115874                                                              16    5631
XP_005260916                                                           16    5631
NP_001001918                                                           16    5631
NP_056477                                                              16    7355
NP_065761                                                              16    7355
NP_055906                                                              16    7355
XP_006720146                                                           16    7355
XP_005267508                                                           16    7355
XP_006712050                                                           16    7355
XP_005264311                                                           16    7355
XP_006712049                                                           16    7355
NP_112217                                                              16    7355
NP_976036                                                              15    9605
NP_002885                                                              15    9605
NP_001186091                                                           15    9605
NP_001186090                                                           15    9605
NP_006668                                                              15    9605
NP_001186089                                                           15    9605
NP_055087                                                              15    9605
NP_079436                                                              15    9605
XP_005258383                                                           15    9605
XP_006722585                                                           15    9605
XP_006722584                                                           15    9605
XP_006722583                                                           15    9605
XP_006722582                                                           15    9605
XP_005254194                                                           15    9605
XP_005264888                                                           15    9605
XP_006713016                                                           15    9605
XP_005264887                                                           15    9605
XP_006713015                                                           15    9605
XP_006713014                                                           15    9605
XP_006713013                                                           15    9605
XP_006713012                                                           15    9605
XP_006713011                                                           15    9605
XP_005264886                                                           15    9605
XP_006713010                                                           15    9605
XP_005264885                                                           15    9605
XP_005264884                                                           15    9605
XP_005264883                                                           15    9605
XP_005264882                                                           15    9605
XP_006713009                                                           15    9605
XP_005264881                                                           15    9605
XP_005264880                                                           15    9605
XP_005273330                                                           15    9605
XP_006711880                                                           15    9605
XP_006711828                                                           15    9605
XP_006711827                                                           15    9605
XP_006711826                                                           15    9605
XP_006710261                                                           15    9605
NP_001001966                                                           15    9605
>NP_060421
          Length = 866

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           H+L+VRL
Sbjct: 365 HVLVVRL 371
>NP_001164554
          Length = 764

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           H+L+VRL
Sbjct: 263 HVLVVRL 269
>NP_148936
          Length = 408

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH LIVR
Sbjct: 208 PHALIVR 214
>NP_001245390
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH LIVR
Sbjct: 322 PHALIVR 328
>NP_006703
          Length = 549

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH LIVR
Sbjct: 349 PHALIVR 355
>NP_060221
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           H+L+VRL
Sbjct: 336 HVLVVRL 342
>XP_005249990
          Length = 515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH LIVR
Sbjct: 315 PHALIVR 321
>XP_005249989
          Length = 515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH LIVR
Sbjct: 315 PHALIVR 321
>XP_005263761
          Length = 530

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  HILIVRL 8
          H+L+VRL
Sbjct: 29 HVLVVRL 35
>XP_006712688
          Length = 559

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  HILIVRL 8
          H+L+VRL
Sbjct: 58 HVLVVRL 64
>NP_056224
          Length = 3123

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    PHILIVR 7
            PH+++VR
Sbjct: 1106 PHLVVVR 1112
>NP_001268449
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PHIL+V
Sbjct: 448 PHILVV 453
>NP_877954
          Length = 824

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PHIL+V
Sbjct: 432 PHILVV 437
>NP_001268450
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PHIL+V
Sbjct: 488 PHILVV 493
>NP_115874
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PHIL+V
Sbjct: 448 PHILVV 453
>XP_005260916
          Length = 581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PHIL+V
Sbjct: 448 PHILVV 453
>NP_001001918
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PHIL+V
Sbjct: 241 PHILVV 246
>NP_056477
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PHILIVRLS 9
           PH++ VR++
Sbjct: 438 PHLISVRIN 446
>NP_065761
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH+ +VR
Sbjct: 577 PHVTVVR 583
>NP_055906
          Length = 1720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           H+L++RL
Sbjct: 419 HLLVIRL 425
>XP_006720146
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           H+L++RL
Sbjct: 419 HLLVIRL 425
>XP_005267508
          Length = 1773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           H+L++RL
Sbjct: 419 HLLVIRL 425
>XP_006712050
          Length = 1716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PHILIVRLS 9
           PH++ VR++
Sbjct: 438 PHLISVRIN 446
>XP_005264311
          Length = 1727

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PHILIVRLS 9
           PH++ VR++
Sbjct: 438 PHLISVRIN 446
>XP_006712049
          Length = 1728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   PHILIVRLS 9
           PH++ VR++
Sbjct: 417 PHLISVRIN 425
>NP_112217
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   HILIVRL 8
           HI++VRL
Sbjct: 292 HIVVVRL 298
>NP_976036
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 794 PHIEVVR 800
>NP_002885
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 794 PHIEVVR 800
>NP_001186091
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1191 PNVLIVQL 1198
>NP_001186090
          Length = 1384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1203 PNVLIVQL 1210
>NP_006668
          Length = 1318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1100 PNVLIVQL 1107
>NP_001186089
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1201 PNVLIVQL 1208
>NP_055087
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   HILIVRL 8
           HI IVRL
Sbjct: 288 HITIVRL 294
>NP_079436
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH ++VR
Sbjct: 189 PHAIVVR 195
>XP_005258383
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 520 PHIEVVR 526
>XP_006722585
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 794 PHIEVVR 800
>XP_006722584
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 794 PHIEVVR 800
>XP_006722583
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 794 PHIEVVR 800
>XP_006722582
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PHI +VR
Sbjct: 794 PHIEVVR 800
>XP_005254194
          Length = 1689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   HILIVRL 8
           HI IVRL
Sbjct: 288 HITIVRL 294
>XP_005264888
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1087 PNVLIVQL 1094
>XP_006713016
          Length = 1404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1186 PNVLIVQL 1193
>XP_005264887
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1104 PNVLIVQL 1111
>XP_006713015
          Length = 1367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1186 PNVLIVQL 1193
>XP_006713014
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1187 PNVLIVQL 1194
>XP_006713013
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1188 PNVLIVQL 1195
>XP_006713012
          Length = 1373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1155 PNVLIVQL 1162
>XP_006713011
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1201 PNVLIVQL 1208
>XP_005264886
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1205 PNVLIVQL 1212
>XP_006713010
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1187 PNVLIVQL 1194
>XP_005264885
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1188 PNVLIVQL 1195
>XP_005264884
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1190 PNVLIVQL 1197
>XP_005264883
          Length = 1421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1203 PNVLIVQL 1210
>XP_005264882
          Length = 1421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1203 PNVLIVQL 1210
>XP_006713009
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1204 PNVLIVQL 1211
>XP_005264881
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1205 PNVLIVQL 1212
>XP_005264880
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    PHILIVRL 8
            P++LIV+L
Sbjct: 1205 PNVLIVQL 1212
>XP_005273330
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH ++VR
Sbjct: 189 PHAIVVR 195
>XP_006711880
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   PHILIVR 7
           PH ++VR
Sbjct: 189 PHAIVVR 195
>XP_006711828
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PH+L+V
Sbjct: 264 PHLLVV 269
>XP_006711827
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PH+L+V
Sbjct: 241 PHLLVV 246
>XP_006711826
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PH+L+V
Sbjct: 264 PHLLVV 269
>XP_006710261
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PHILIVRLS 9
           P +LI RLS
Sbjct: 294 PDVLIPRLS 302
>NP_001001966
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   PHILIV 6
           PH+L+V
Sbjct: 241 PHLLVV 246
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.155    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 394,158
Number of extensions: 578
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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