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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_112484                                                              16    7355
NP_001230455                                                           16    7355
NP_001177809                                                           16    7355
NP_056044                                                              16    7355
NP_001073944                                                           16    7355
NP_113618                                                              16    7355
XP_006725320                                                           16    7355
XP_006725319                                                           16    7355
XP_005256868                                                           16    7355
XP_006721649                                                           16    7355
XP_005256625                                                           16    7355
XP_005256624                                                           16    7355
XP_005256622                                                           16    7355
XP_006721555                                                           16    7355
XP_006721554                                                           16    7355
XP_005246602                                                           16    7355
XP_006712584                                                           16    7355
XP_005246601                                                           16    7355
XP_005246600                                                           16    7355
XP_005271297                                                           16    7355
XP_006711000                                                           16    7355
XP_005271296                                                           16    7355
NP_004111                                                              15    9605
NP_003214                                                              15    9605
NP_064579                                                              15    9605
NP_001263997                                                           15    9605
NP_002044                                                              15    9605
NP_001263992                                                           15    9605
NP_001263995                                                           15    9605
NP_001263991                                                           15    9605
NP_001263993                                                           15    9605
NP_001263994                                                           15    9605
NP_001263990                                                           15    9605
NP_065118                                                              15    9605
NP_060754                                                              15    9605
NP_001266280                                                           15    9605
NP_001266279                                                           15    9605
XP_006712702                                                           15    9605
XP_005246745                                                           15    9605
XP_005246744                                                           15    9605
XP_005246743                                                           15    9605
XP_005246742                                                           15    9605
XP_006712701                                                           15    9605
XP_005246741                                                           15    9605
XP_006712700                                                           15    9605
XP_005246740                                                           15    9605
XP_005246739                                                           15    9605
XP_005246738                                                           15    9605
XP_005270798                                                           15    9605
XP_006710637                                                           15    9605

>NP_112484
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEAL  AAR
Sbjct: 45 PEALARAAR 53



>NP_001230455
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEAL  AAR
Sbjct: 45 PEALARAAR 53



>NP_001177809
          Length = 277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEAL  AAR
Sbjct: 45 PEALARAAR 53



>NP_056044
          Length = 1309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    PEALKVA 7
            P+ALKVA
Sbjct: 1140 PKALKVA 1146



>NP_001073944
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EALKVAA 8
           EALK+AA
Sbjct: 449 EALKIAA 455



>NP_113618
          Length = 401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EALKVAAR 9
           EA+KVA R
Sbjct: 288 EAMKVAVR 295



>XP_006725320
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EALKVAAR 9
           EA+KVA R
Sbjct: 288 EAMKVAVR 295



>XP_006725319
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EALKVAAR 9
           EA+KVA R
Sbjct: 286 EAMKVAVR 293



>XP_005256868
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EALKVAAR 9
           EA+KVA R
Sbjct: 288 EAMKVAVR 295



>XP_006721649
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EALKVAAR 9
           EA+KVA R
Sbjct: 286 EAMKVAVR 293



>XP_005256625
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    PEALKVA 7
            P+ALKVA
Sbjct: 1178 PKALKVA 1184



>XP_005256624
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    PEALKVA 7
            P+ALKVA
Sbjct: 1179 PKALKVA 1185



>XP_005256622
          Length = 1383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    PEALKVA 7
            P+ALKVA
Sbjct: 1214 PKALKVA 1220



>XP_006721555
          Length = 1444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    PEALKVA 7
            P+ALKVA
Sbjct: 1275 PKALKVA 1281



>XP_006721554
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    PEALKVA 7
            P+ALKVA
Sbjct: 1276 PKALKVA 1282



>XP_005246602
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EALKVAA 8
           EALK+AA
Sbjct: 449 EALKIAA 455



>XP_006712584
          Length = 657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EALKVAA 8
           EALK+AA
Sbjct: 449 EALKIAA 455



>XP_005246601
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EALKVAA 8
           EALK+AA
Sbjct: 449 EALKIAA 455



>XP_005246600
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EALKVAA 8
           EALK+AA
Sbjct: 449 EALKIAA 455



>XP_005271297
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEAL  AAR
Sbjct: 45 PEALARAAR 53



>XP_006711000
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEAL  AAR
Sbjct: 45 PEALARAAR 53



>XP_005271296
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEAL  AAR
Sbjct: 45 PEALARAAR 53



>NP_004111
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PEALKV 6
          PEALK+
Sbjct: 25 PEALKI 30



>NP_003214
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PEALKVAAR 9
           PE LKV A+
Sbjct: 185 PEKLKVIAQ 193



>NP_064579
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>NP_001263997
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>NP_002044
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PEALKV 6
          PEALK+
Sbjct: 25 PEALKI 30



>NP_001263992
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>NP_001263995
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>NP_001263991
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>NP_001263993
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>NP_001263994
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>NP_001263990
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>NP_065118
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PEALKVAAR 9
           PEA K+A +
Sbjct: 210 PEAAKIARK 218



>NP_060754
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PEALKV 6
          PEALK+
Sbjct: 25 PEALKI 30



>NP_001266280
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PEALKVAAR 9
           PEA K+A +
Sbjct: 117 PEAAKIARK 125



>NP_001266279
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PEALKVAAR 9
          PEA K+A +
Sbjct: 73 PEAAKIARK 81



>XP_006712702
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>XP_005246745
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_005246744
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_005246743
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_005246742
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_006712701
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>XP_005246741
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_006712700
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>XP_005246740
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 24 PEKLKVA 30



>XP_005246739
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_005246738
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  PEALKVA 7
          PE LKVA
Sbjct: 50 PEKLKVA 56



>XP_005270798
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PEALKV 6
          PEALK+
Sbjct: 25 PEALKI 30



>XP_006710637
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PEALKV 6
          PEALK+
Sbjct: 25 PEALKI 30



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.123    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,040
Number of extensions: 556
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)