Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
NP_940892                                                              17    3301
NP_001191814                                                           17    3301
NP_001191813                                                           17    3301
NP_001191815                                                           17    3301
NP_001191812                                                           17    3301
NP_060868                                                              17    4312
XP_005265376                                                           17    4312
XP_005265375                                                           17    4312
NP_001139791                                                           16    5631
NP_002009                                                              16    5631
NP_001243193                                                           16    5631
NP_001243194                                                           16    5631
XP_005256615                                                           16    5631
XP_005256613                                                           16    5631
XP_005256612                                                           16    5631
NP_057331                                                              16    7355
NP_001129628                                                           16    7355
NP_055897                                                              16    7355
NP_055061                                                              16    7355
NP_055725                                                              16    7355
XP_006724446                                                           16    7355
NP_001005619                                                           15    9605
NP_001005731                                                           15    9605
NP_000204                                                              15    9605
NP_001036236                                                           15    9605
NP_005347                                                              15    9605
NP_001244961                                                           15    9605
NP_001244960                                                           15    9605
NP_938020                                                              15    9605
XP_006724542                                                           15    9605
XP_005274533                                                           15    9605
XP_005274532                                                           15    9605
XP_006724541                                                           15    9605
XP_005274531                                                           15    9605
XP_006724540                                                           15    9605
XP_005274530                                                           15    9605
XP_005257369                                                           15    9605
XP_005257368                                                           15    9605
XP_006721933                                                           15    9605
XP_006721932                                                           15    9605
XP_006721931                                                           15    9605
XP_006721930                                                           15    9605
XP_005257366                                                           15    9605
XP_006721929                                                           15    9605
XP_005270921                                                           15    9605
XP_005270920                                                           15    9605
XP_005270919                                                           15    9605
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1735 PVVSLAEAQ 1743
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1735 PVVSLAEAQ 1743
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1691 PVVSLAEAQ 1699
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P VSLAEAQ
Sbjct: 742 PVVSLAEAQ 750
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1691 PVVSLAEAQ 1699
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1800 PVVSLAEAQ 1808
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1734 PVVSLAEAQ 1742
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1735 PVVSLAEAQ 1743
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1738 PVVSLAEAQ 1746
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1788 PVVSLAEAQ 1796
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1800 PVVSLAEAQ 1808
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1801 PVVSLAEAQ 1809
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1897 PVVSLAEAQ 1905
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDVSLAEAQ 9
            P VSLAEAQ
Sbjct: 1898 PVVSLAEAQ 1906
>NP_940892
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DVSLAEAQ 9
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191814
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DVSLAEAQ 9
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191813
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DVSLAEAQ 9
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191815
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DVSLAEAQ 9
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191812
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   DVSLAEAQ 9
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_060868
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PDVSLAE 7
           PDVSLA+
Sbjct: 645 PDVSLAD 651
>XP_005265376
          Length = 877

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PDVSLAE 7
           PDVSLA+
Sbjct: 645 PDVSLAD 651
>XP_005265375
          Length = 1085

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   PDVSLAE 7
           PDVSLA+
Sbjct: 639 PDVSLAD 645
>NP_001139791
          Length = 447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  PDVSLAEAQ 9
          PD+ L+EA+
Sbjct: 39 PDLELSEAE 47
>NP_002009
          Length = 1269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P +SLAEA+
Sbjct: 886 PPMSLAEAE 894
>NP_001243193
          Length = 1258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P +SLAEA+
Sbjct: 875 PPMSLAEAE 883
>NP_001243194
          Length = 1214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P +SLAEA+
Sbjct: 831 PPMSLAEAE 839
>XP_005256615
          Length = 1268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P +SLAEA+
Sbjct: 885 PPMSLAEAE 893
>XP_005256613
          Length = 1295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P +SLAEA+
Sbjct: 885 PPMSLAEAE 893
>XP_005256612
          Length = 1296

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PDVSLAEAQ 9
           P +SLAEA+
Sbjct: 886 PPMSLAEAE 894
>NP_057331
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PDVSLAEA 8
           PD S+AEA
Sbjct: 93  PDESVAEA 100
>NP_001129628
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SL EAQ
Sbjct: 425 DLSLTEAQ 432
>NP_055897
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  PDVSLAEAQ 9
          PDV + E+Q
Sbjct: 32 PDVGVGESQ 40
>NP_055061
          Length = 3014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    PDVSLAEA 8
            PD SLAE+
Sbjct: 2864 PDQSLAES 2871
>NP_055725
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SL EAQ
Sbjct: 425 DLSLTEAQ 432
>XP_006724446
          Length = 3019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    PDVSLAEA 8
            PD SLAE+
Sbjct: 2864 PDQSLAES 2871
>NP_001005619
          Length = 1805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1330 PDIPIVDAQ 1338
>NP_001005731
          Length = 1752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1330 PDIPIVDAQ 1338
>NP_000204
          Length = 1822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1330 PDIPIVDAQ 1338
>NP_001036236
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PDVSLAEA 8
           PD  LAEA
Sbjct: 282 PDAFLAEA 289
>NP_005347
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PDVSLAEA 8
           PD  LAEA
Sbjct: 282 PDAFLAEA 289
>NP_001244961
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PDVSLA 6
          PD+SLA
Sbjct: 92 PDISLA 97
>NP_001244960
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDVSLA 6
           PD+SLA
Sbjct: 336 PDISLA 341
>NP_938020
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_006724542
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274533
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274532
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_006724541
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274531
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 505 DMSLAELQ 512
>XP_006724540
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274530
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVSLAEAQ 9
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005257369
          Length = 1752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1330 PDIPIVDAQ 1338
>XP_005257368
          Length = 1875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1330 PDIPIVDAQ 1338
>XP_006721933
          Length = 1787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1365 PDIPIVDAQ 1373
>XP_006721932
          Length = 1821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1276 PDIPIVDAQ 1284
>XP_006721931
          Length = 1840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1365 PDIPIVDAQ 1373
>XP_006721930
          Length = 1857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1365 PDIPIVDAQ 1373
>XP_005257366
          Length = 1875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1330 PDIPIVDAQ 1338
>XP_006721929
          Length = 1910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDVSLAEAQ 9
            PD+ + +AQ
Sbjct: 1365 PDIPIVDAQ 1373
>XP_005270921
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PDVSLAEA 8
           PD  LAEA
Sbjct: 326 PDAFLAEA 333
>XP_005270920
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PDVSLAEA 8
           PD  LAEA
Sbjct: 340 PDAFLAEA 347
>XP_005270919
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PDVSLAEA 8
           PD  LAEA
Sbjct: 340 PDAFLAEA 347
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.117    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 409,942
Number of extensions: 650
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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