Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              21     175
NP_001075109                                                           21     175
NP_001276928                                                           17    4312
NP_001276929                                                           17    4312
NP_005375                                                              17    4312
NP_005547                                                              16    5631
NP_060724                                                              16    5631
NP_001129695                                                           16    5631
NP_001129697                                                           16    5631
NP_001129696                                                           16    5631
NP_001265455                                                           16    5631
NP_001265454                                                           16    5631
NP_001265453                                                           16    5631
NP_055618                                                              16    5631
NP_001092108                                                           16    5631
NP_942600                                                              16    5631
XP_005274448                                                           16    5631
XP_006711507                                                           16    5631
XP_006711506                                                           16    5631
XP_006711505                                                           16    5631
XP_005273248                                                           16    5631
NP_001004339                                                           16    7355
NP_951059                                                              15    9605
NP_060119                                                              15    9605
NP_951058                                                              15    9605
NP_001191339                                                           15    9605
NP_002994                                                              15    9605
NP_001002858                                                           15    9605
NP_001129487                                                           15    9605
NP_055627                                                              15    9605
NP_001035864                                                           15    9605
NP_004030                                                              15    9605
NP_001002857                                                           15    9605
NP_001035863                                                           15    9605
NP_001137473                                                           15    9605
NP_001137471                                                           15    9605
NP_001137470                                                           15    9605
NP_001191337                                                           15    9605
NP_005773                                                              15    9605
NP_001034662                                                           15    9605
NP_064569                                                              15    9605
XP_006725047                                                           15    9605
XP_006725046                                                           15    9605
XP_006725045                                                           15    9605
XP_006725044                                                           15    9605
XP_006725043                                                           15    9605
XP_006725042                                                           15    9605
XP_006725041                                                           15    9605
XP_006725040                                                           15    9605
XP_006725039                                                           15    9605
XP_006725038                                                           15    9605
XP_006725037                                                           15    9605
XP_006717971                                                           15    9605
XP_005269990                                                           15    9605
XP_005263972                                                           15    9605
XP_005263971                                                           15    9605
XP_006711915                                                           15    9605
XP_006711914                                                           15    9605
XP_006711913                                                           15    9605
XP_006711912                                                           15    9605
XP_006711911                                                           15    9605
XP_005273418                                                           15    9605
XP_006711910                                                           15    9605
XP_006711909                                                           15    9605
XP_006711908                                                           15    9605
XP_006711907                                                           15    9605
XP_006711906                                                           15    9605
>NP_008835
          Length = 4128

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDAKMDAMN 9
            PDAKMD MN
Sbjct: 3169 PDAKMDPMN 3177
>NP_001075109
          Length = 4097

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PDAKMDAMN 9
            PDAKMD MN
Sbjct: 3169 PDAKMDPMN 3177
>NP_001276928
          Length = 462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PDAKMDAM 8
          PD K DAM
Sbjct: 68 PDEKKDAM 75
>NP_001276929
          Length = 462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PDAKMDAM 8
          PD K DAM
Sbjct: 68 PDEKKDAM 75
>NP_005375
          Length = 462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  PDAKMDAM 8
          PD K DAM
Sbjct: 68 PDEKKDAM 75
>NP_005547
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DAKMDAMN 9
           +AK+DA+N
Sbjct: 212 EAKVDALN 219
>NP_060724
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  PDAKMD 6
          PDAK+D
Sbjct: 39 PDAKLD 44
>NP_001129695
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 97  PDAKLD 102
>NP_001129697
          Length = 449

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 97  PDAKLD 102
>NP_001129696
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 97  PDAKLD 102
>NP_001265455
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PDAKMDAMN 9
           PD K D+ N
Sbjct: 265 PDVKQDSSN 273
>NP_001265454
          Length = 1483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PDAKMDAMN 9
           PD K D+ N
Sbjct: 795 PDVKQDSSN 803
>NP_001265453
          Length = 1483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PDAKMDAMN 9
           PD K D+ N
Sbjct: 795 PDVKQDSSN 803
>NP_055618
          Length = 1483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PDAKMDAMN 9
           PD K D+ N
Sbjct: 795 PDVKQDSSN 803
>NP_001092108
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 555 PDAKLD 560
>NP_942600
          Length = 364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PDAKMDAMN 9
           PD++MD M+
Sbjct: 222 PDSQMDDMD 230
>XP_005274448
          Length = 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PDAKMDAMN 9
           PD++MD M+
Sbjct: 118 PDSQMDDMD 126
>XP_006711507
          Length = 354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 98  PDAKLD 103
>XP_006711506
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 98  PDAKLD 103
>XP_006711505
          Length = 437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 98  PDAKLD 103
>XP_005273248
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   PDAKMD 6
           PDAK+D
Sbjct: 98  PDAKLD 103
>NP_001004339
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  PDAKMDAM 8
          PDA+ DA+
Sbjct: 17 PDAQKDAL 24
>NP_951059
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 528 DTKLDAM 534
>NP_060119
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 528 DTKLDAM 534
>NP_951058
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 528 DTKLDAM 534
>NP_001191339
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 235 PDDKLDA 241
>NP_002994
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 235 PDDKLDA 241
>NP_001002858
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DAKMDAMN 9
          DA+ DA+N
Sbjct: 52 DAERDALN 59
>NP_001129487
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DAKMDAMN 9
          DA+ DA+N
Sbjct: 34 DAERDALN 41
>NP_055627
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1496 PDGTLEALN 1504
>NP_001035864
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1372 PDGTLEALN 1380
>NP_004030
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DAKMDAMN 9
          DA+ DA+N
Sbjct: 34 DAERDALN 41
>NP_001002857
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DAKMDAMN 9
          DA+ DA+N
Sbjct: 34 DAERDALN 41
>NP_001035863
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1398 PDGTLEALN 1406
>NP_001137473
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 201 PDDKLDA 207
>NP_001137471
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 235 PDDKLDA 241
>NP_001137470
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 235 PDDKLDA 241
>NP_001191337
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 235 PDDKLDA 241
>NP_005773
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DAKMDAMN 9
           DA++DA N
Sbjct: 251 DAQLDAYN 258
>NP_001034662
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   PDAKMDA 7
           PD K+DA
Sbjct: 235 PDDKLDA 241
>NP_064569
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 455 DTKLDAM 461
>XP_006725047
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1372 PDGTLEALN 1380
>XP_006725046
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1398 PDGTLEALN 1406
>XP_006725045
          Length = 1496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1408 PDGTLEALN 1416
>XP_006725044
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1496 PDGTLEALN 1504
>XP_006725043
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1505 PDGTLEALN 1513
>XP_006725042
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1506 PDGTLEALN 1514
>XP_006725041
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1522 PDGTLEALN 1530
>XP_006725040
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1532 PDGTLEALN 1540
>XP_006725039
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1541 PDGTLEALN 1549
>XP_006725038
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1558 PDGTLEALN 1566
>XP_006725037
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1568 PDGTLEALN 1576
>XP_006717971
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 528 DTKLDAM 534
>XP_005269990
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 528 DTKLDAM 534
>XP_005263972
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 455 DTKLDAM 461
>XP_005263971
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DAKMDAM 8
           D K+DAM
Sbjct: 455 DTKLDAM 461
>XP_006711915
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1372 PDGTLEALN 1380
>XP_006711914
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1398 PDGTLEALN 1406
>XP_006711913
          Length = 1496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1408 PDGTLEALN 1416
>XP_006711912
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1496 PDGTLEALN 1504
>XP_006711911
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1505 PDGTLEALN 1513
>XP_005273418
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1506 PDGTLEALN 1514
>XP_006711910
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1522 PDGTLEALN 1530
>XP_006711909
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1532 PDGTLEALN 1540
>XP_006711908
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1541 PDGTLEALN 1549
>XP_006711907
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1558 PDGTLEALN 1566
>XP_006711906
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    PDAKMDAMN 9
            PD  ++A+N
Sbjct: 1568 PDGTLEALN 1576
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.120    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 477,623
Number of extensions: 980
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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