Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              20     390
NP_005913                                                              20     390
XP_005267046                                                           20     390
XP_005267045                                                           20     390
NP_005091                                                              18    1935
NP_653080                                                              18    1935
NP_004873                                                              18    1935
XP_005267292                                                           18    1935
XP_005267291                                                           18    1935
XP_005267290                                                           18    1935
NP_004477                                                              17    2528
NP_036238                                                              17    2528
XP_005251989                                                           17    2528
XP_005251988                                                           17    2528
XP_005251987                                                           17    2528
NP_002660                                                              17    3301
NP_001188493                                                           17    3301
XP_005249774                                                           17    3301
NP_006175                                                              17    4312
NP_005473                                                              17    4312
NP_001034859                                                           17    4312
NP_001129710                                                           17    4312
NP_001230469                                                           16    5631
NP_056125                                                              16    5631
NP_004425                                                              16    5631
NP_001230470                                                           16    5631
XP_005256979                                                           16    5631
XP_006721694                                                           16    5631
XP_006720137                                                           16    5631
XP_005267457                                                           16    5631
XP_005267456                                                           16    5631
XP_005267455                                                           16    5631
XP_005267454                                                           16    5631
XP_005273518                                                           16    5631
XP_006716381                                                           16    5631
NP_006477                                                              16    7355
NP_055244                                                              16    7355
NP_036381                                                              16    7355
NP_113623                                                              16    7355
NP_002902                                                              16    7355
XP_005260072                                                           16    7355
XP_005247419                                                           16    7355
NP_060945                                                              15    9605
NP_001116856                                                           15    9605
NP_001116855                                                           15    9605
NP_060215                                                              15    9605
NP_001116857                                                           15    9605
NP_001278425                                                           15    9605
NP_001035531                                                           15    9605
NP_057251                                                              15    9605
NP_003615                                                              15    9605
NP_015561                                                              15    9605
NP_060834                                                              15    9605
NP_115272                                                              15    9605
NP_061750                                                              15    9605
NP_060903                                                              15    9605
NP_001140160                                                           15    9605
XP_005272677                                                           15    9605
XP_005272676                                                           15    9605
XP_005272675                                                           15    9605
XP_005272674                                                           15    9605
XP_006724599                                                           15    9605
XP_005272673                                                           15    9605
XP_005249230                                                           15    9605
XP_006712114                                                           15    9605
>NP_006715
          Length = 1558

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PASQSNLKE 9
           PAS+SNLKE
Sbjct: 107 PASRSNLKE 115
>NP_005913
          Length = 1608

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PASQSNLKE 9
           PAS+SNLKE
Sbjct: 107 PASRSNLKE 115
>XP_005267046
          Length = 1554

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PASQSNLKE 9
           PAS+SNLKE
Sbjct: 107 PASRSNLKE 115
>XP_005267045
          Length = 1604

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   PASQSNLKE 9
           PAS+SNLKE
Sbjct: 107 PASRSNLKE 115
>NP_005091
          Length = 1782

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PASQSNLKE 9
           P+S+SNL+E
Sbjct: 150 PSSESNLEE 158
>NP_653080
          Length = 1684

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  PASQSNLKE 9
          P+S+SNL+E
Sbjct: 52 PSSESNLEE 60
>NP_004873
          Length = 450

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  PASQSNLKE 9
          PAS+SN+K+
Sbjct: 16 PASKSNIKK 24
>XP_005267292
          Length = 1677

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  PASQSNLKE 9
          P+S+SNL+E
Sbjct: 45 PSSESNLEE 53
>XP_005267291
          Length = 1684

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  PASQSNLKE 9
          P+S+SNL+E
Sbjct: 52 PSSESNLEE 60
>XP_005267290
          Length = 1782

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   PASQSNLKE 9
           P+S+SNL+E
Sbjct: 150 PSSESNLEE 158
>NP_004477
          Length = 1002

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS +NLK+
Sbjct: 150 PASSANLKD 158
>NP_036238
          Length = 163

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PASQ+NL+
Sbjct: 155 PASQNNLR 162
>XP_005251989
          Length = 975

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS +NLK+
Sbjct: 150 PASSANLKD 158
>XP_005251988
          Length = 1002

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS +NLK+
Sbjct: 177 PASSANLKD 185
>XP_005251987
          Length = 1029

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS +NLK+
Sbjct: 177 PASSANLKD 185
>NP_002660
          Length = 514

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PASQSNLKE 9
          P S+ NLKE
Sbjct: 59 PTSKENLKE 67
>NP_001188493
          Length = 505

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  PASQSNLKE 9
          P S+ NLKE
Sbjct: 59 PTSKENLKE 67
>XP_005249774
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PASQSNLKE 9
          PAS++NL E
Sbjct: 39 PASRTNLSE 47
>NP_006175
          Length = 461

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           P SQ+ LKE
Sbjct: 222 PGSQAQLKE 230
>NP_005473
          Length = 395

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PASQ+N+ +
Sbjct: 262 PASQTNMND 270
>NP_001034859
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   PASQSNLK 8
           PAS +NLK
Sbjct: 201 PASMNNLK 208
>NP_001129710
          Length = 316

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  PASQSNLK 8
          PAS +NLK
Sbjct: 64 PASMNNLK 71
>NP_001230469
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PASQ  L+E
Sbjct: 325 PASQCTLRE 333
>NP_056125
          Length = 1047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PASQSNLKE 9
           PA Q NL E
Sbjct: 188 PAGQKNLPE 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SQSNLKE 9
           SQS+LKE
Sbjct: 119 SQSHLKE 125
>NP_004425
          Length = 815

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PA++SN+K
Sbjct: 124 PATKSNIK 131
>NP_001230470
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PASQ  L+E
Sbjct: 267 PASQCTLRE 275
>XP_005256979
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PASQ  L+E
Sbjct: 267 PASQCTLRE 275
>XP_006721694
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PASQ  L+E
Sbjct: 325 PASQCTLRE 333
>XP_006720137
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PA++SN+K
Sbjct: 124 PATKSNIK 131
>XP_005267457
          Length = 802

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PA++SN+K
Sbjct: 111 PATKSNIK 118
>XP_005267456
          Length = 815

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PA++SN+K
Sbjct: 105 PATKSNIK 112
>XP_005267455
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PA++SN+K
Sbjct: 111 PATKSNIK 118
>XP_005267454
          Length = 834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   PASQSNLK 8
           PA++SN+K
Sbjct: 124 PATKSNIK 131
>XP_005273518
          Length = 732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PASQSNLKE 9
           PA Q NL E
Sbjct: 188 PAGQKNLPE 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SQSNLKE 9
           SQS+LKE
Sbjct: 119 SQSHLKE 125
>XP_006716381
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   PASQSNLKE 9
           PA Q NL E
Sbjct: 155 PAGQKNLPE 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SQSNLKE 9
          SQS+LKE
Sbjct: 86 SQSHLKE 92
>NP_006477
          Length = 703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   PASQSNL 7
           PASQ+N+
Sbjct: 626 PASQANI 632
>NP_055244
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ASQSNLKE 9
           A Q NLKE
Sbjct: 334 AKQKNLKE 341
>NP_036381
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PAS  N+KE
Sbjct: 93  PASFQNVKE 101
>NP_113623
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   PASQSNLK 8
           PA  SNLK
Sbjct: 105 PAGPSNLK 112
>NP_002902
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASQSNLKE 9
           ASQS+LK+
Sbjct: 214 ASQSSLKD 221
>XP_005260072
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ASQSNLKE 9
           ASQS+LK+
Sbjct: 214 ASQSSLKD 221
>XP_005247419
          Length = 1014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ASQSNLKE 9
           A Q NLKE
Sbjct: 334 AKQKNLKE 341
>NP_060945
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  PASQSNL 7
          PA+Q+NL
Sbjct: 85 PATQTNL 91
>NP_001116856
          Length = 1703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1266 PAKQQKIKE 1274
>NP_001116855
          Length = 1721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1284 PAKQQKIKE 1292
>NP_060215
          Length = 1721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1284 PAKQQKIKE 1292
>NP_001116857
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1318 PAKQQKIKE 1326
>NP_001278425
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PASQ N ++
Sbjct: 187 PASQKNTQQ 195
>NP_001035531
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PASQ N ++
Sbjct: 187 PASQKNTQQ 195
>NP_057251
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ASQSNLKE 9
           ASQ+N+K+
Sbjct: 125 ASQTNIKK 132
>NP_003615
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PASQSNLKE 9
          PA Q NL +
Sbjct: 28 PAEQKNLSD 36
>NP_015561
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PASQSNLKE 9
          PA Q NL +
Sbjct: 28 PAEQKNLSD 36
>NP_060834
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS+ NL++
Sbjct: 762 PASELNLQQ 770
>NP_115272
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PA+Q NL +
Sbjct: 775 PATQDNLNK 783
>NP_061750
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PASQSNLKE 9
           PA+Q NL +
Sbjct: 775 PATQDNLNK 783
>NP_060903
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS+ +LK+
Sbjct: 764 PASKEDLKQ 772
>NP_001140160
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS+ +LK+
Sbjct: 764 PASKEDLKQ 772
>XP_005272677
          Length = 1703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1266 PAKQQKIKE 1274
>XP_005272676
          Length = 1737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1300 PAKQQKIKE 1308
>XP_005272675
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1318 PAKQQKIKE 1326
>XP_005272674
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1318 PAKQQKIKE 1326
>XP_006724599
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1318 PAKQQKIKE 1326
>XP_005272673
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    PASQSNLKE 9
            PA Q  +KE
Sbjct: 1318 PAKQQKIKE 1326
>XP_005249230
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ASQSNLKE 9
           ASQ+N+K+
Sbjct: 125 ASQTNIKK 132
>XP_006712114
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   PASQSNLKE 9
           PAS+ +LK+
Sbjct: 104 PASKEDLKQ 112
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.284    0.103    0.250 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 540,533
Number of extensions: 1155
Number of successful extensions: 68
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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