Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              20     509
NP_009297                                                              20     509
NP_001243778                                                           18    1482
NP_002682                                                              18    1482
XP_005259065                                                           18    1482
XP_006723311                                                           18    1482
XP_005259064                                                           18    1482
XP_005259063                                                           18    1482
NP_066009                                                              18    1935
NP_478144                                                              18    1935
NP_055969                                                              17    2528
NP_037486                                                              17    4312
NP_473367                                                              17    4312
NP_004708                                                              17    4312
XP_005273538                                                           17    4312
XP_006716236                                                           17    4312
XP_006716235                                                           17    4312
NP_054878                                                              16    5631
XP_005265151                                                           16    5631
XP_006713183                                                           16    5631
XP_006713182                                                           16    5631
NP_001259031                                                           16    7355
NP_001121371                                                           16    7355
NP_001121370                                                           16    7355
NP_001073922                                                           16    7355
XP_005253228                                                           16    7355
NP_002830                                                              15    9605
NP_001245308                                                           15    9605
NP_003606                                                              15    9605
NP_001245309                                                           15    9605
NP_001171486                                                           15    9605
NP_001171487                                                           15    9605
NP_899180                                                              15    9605
NP_003825                                                              15    9605
XP_005251759                                                           15    9605
XP_005251758                                                           15    9605
XP_006716891                                                           15    9605
XP_006716890                                                           15    9605
XP_006716889                                                           15    9605
XP_006716888                                                           15    9605
XP_006716887                                                           15    9605
XP_006716886                                                           15    9605
XP_006716885                                                           15    9605
XP_006716884                                                           15    9605
XP_006716883                                                           15    9605
XP_006716882                                                           15    9605
XP_006716881                                                           15    9605
XP_006716880                                                           15    9605
XP_006716879                                                           15    9605
XP_006716878                                                           15    9605
XP_006716877                                                           15    9605
XP_006716876                                                           15    9605
XP_005265658                                                           15    9605
XP_005265657                                                           15    9605
XP_005265656                                                           15    9605
XP_005265655                                                           15    9605
XP_006713484                                                           15    9605
XP_005246753                                                           15    9605
XP_005246752                                                           15    9605
XP_005246751                                                           15    9605
XP_006712706                                                           15    9605
XP_006712705                                                           15    9605
XP_006712704                                                           15    9605
XP_005246750                                                           15    9605
NP_071341                                                              15    9605
NP_689633                                                              15    9605
>NP_005148
          Length = 1130

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PAATLDFSK 9
            PAAT DFSK
Sbjct: 1108 PAATQDFSK 1116
>NP_009297
          Length = 1149

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    PAATLDFSK 9
            PAAT DFSK
Sbjct: 1127 PAATQDFSK 1135
>NP_001243778
          Length = 1107

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           P ATLDFS
Sbjct: 597 PIATLDFS 604
>NP_002682
          Length = 1107

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           P ATLDFS
Sbjct: 597 PIATLDFS 604
>XP_005259065
          Length = 1083

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           P ATLDFS
Sbjct: 597 PIATLDFS 604
>XP_006723311
          Length = 1109

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           P ATLDFS
Sbjct: 623 PIATLDFS 630
>XP_005259064
          Length = 1133

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           P ATLDFS
Sbjct: 623 PIATLDFS 630
>XP_005259063
          Length = 1133

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           P ATLDFS
Sbjct: 623 PIATLDFS 630
>NP_066009
          Length = 120

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PAATLDFSK 9
          PAA +DFS+
Sbjct: 6  PAAAMDFSQ 14
>NP_478144
          Length = 873

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PAATLDFSK 9
          PAA +DFS+
Sbjct: 6  PAAAMDFSQ 14
>NP_055969
          Length = 234

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PAATLDFSK 9
          P+A +DFSK
Sbjct: 87 PSAPVDFSK 95
>NP_037486
          Length = 285

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PAATLDFSK 9
          PAAT+D S+
Sbjct: 2  PAATVDHSQ 10
>NP_473367
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PAATLDFSK 9
          PAAT+D S+
Sbjct: 2  PAATVDHSQ 10
>NP_004708
          Length = 1065

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PAATLDFSK 9
           P ATLD+S+
Sbjct: 163 PRATLDWSE 171
>XP_005273538
          Length = 285

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  PAATLDFSK 9
          PAAT+D S+
Sbjct: 2  PAATVDHSQ 10
>XP_006716236
          Length = 1022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PAATLDFSK 9
           P ATLD+S+
Sbjct: 111 PRATLDWSE 119
>XP_006716235
          Length = 1057

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   PAATLDFSK 9
           P ATLD+S+
Sbjct: 163 PRATLDWSE 171
>NP_054878
          Length = 2564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  T+D+SK
Sbjct: 764 PVMTVDYSK 772
>XP_005265151
          Length = 2058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  T+D+SK
Sbjct: 764 PVMTVDYSK 772
>XP_006713183
          Length = 2258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  T+D+SK
Sbjct: 764 PVMTVDYSK 772
>XP_006713182
          Length = 2422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  T+D+SK
Sbjct: 764 PVMTVDYSK 772
>NP_001259031
          Length = 64

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PAATLDFS 8
          PA  +DFS
Sbjct: 34 PATAMDFS 41
>NP_001121371
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PAATLDFS 8
          PA  +DFS
Sbjct: 34 PATAMDFS 41
>NP_001121370
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  PAATLDFS 8
          PA  +DFS
Sbjct: 34 PATAMDFS 41
>NP_001073922
          Length = 2190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    PAATLDF 7
            P+A+LDF
Sbjct: 1691 PSASLDF 1697
>XP_005253228
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           PAAT+D  +
Sbjct: 461 PAATVDLGR 469
>NP_002830
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>NP_001245308
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 288 STVDFSK 294
>NP_003606
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 407 STVDFSK 413
>NP_001245309
          Length = 1090

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 283 STVDFSK 289
>NP_001171486
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 280 STVDFSK 286
>NP_001171487
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 291 STVDFSK 297
>NP_899180
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           PAA LD++
Sbjct: 117 PAAELDYA 124
>NP_003825
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   PAATLDFS 8
           PAA LD++
Sbjct: 96  PAAELDYA 103
>XP_005251759
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PAATLDFSK 9
          PA+T D  K
Sbjct: 70 PASTFDMDK 78
>XP_005251758
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  PAATLDFSK 9
          PA+T D  K
Sbjct: 80 PASTFDMDK 88
>XP_006716891
          Length = 1882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 817 PLTTLEFSE 825
>XP_006716890
          Length = 1893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 845 PLTTLEFSE 853
>XP_006716889
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 854 PLTTLEFSE 862
>XP_006716888
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716887
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716886
          Length = 1913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716885
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716884
          Length = 1922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 858 PLTTLEFSE 866
>XP_006716883
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 858 PLTTLEFSE 866
>XP_006716882
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716881
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 863 PLTTLEFSE 871
>XP_006716880
          Length = 1929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716879
          Length = 1931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716878
          Length = 1931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716877
          Length = 1931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_006716876
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   PAATLDFSK 9
           P  TL+FS+
Sbjct: 867 PLTTLEFSE 875
>XP_005265658
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 288 STVDFSK 294
>XP_005265657
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 270 STVDFSK 276
>XP_005265656
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 275 STVDFSK 281
>XP_005265655
          Length = 1126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 283 STVDFSK 289
>XP_006713484
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 412 STVDFSK 418
>XP_005246753
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 349 STVDFSK 355
>XP_005246752
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 291 STVDFSK 297
>XP_005246751
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 291 STVDFSK 297
>XP_006712706
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 292 STVDFSK 298
>XP_006712705
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 348 STVDFSK 354
>XP_006712704
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 348 STVDFSK 354
>XP_005246750
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 349 STVDFSK 355
>NP_071341
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATLDFSK 9
           +T+DFSK
Sbjct: 280 STVDFSK 286
>NP_689633
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   PAATLDFSK 9
           PA+T D  K
Sbjct: 149 PASTFDMDK 157
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.125    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 503,757
Number of extensions: 975
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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