Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           21     175
NP_055903                                                              21     175
NP_009124                                                              17    3301
XP_006714136                                                           17    3301
NP_001654                                                              17    4312
NP_001019398                                                           17    4312
NP_001019397                                                           17    4312
NP_001019399                                                           17    4312
NP_001650                                                              17    4312
NP_001649                                                              17    4312
NP_001035089                                                           17    4312
NP_001193937                                                           17    4312
NP_001653                                                              17    4312
XP_006719454                                                           17    4312
XP_005268913                                                           17    4312
XP_006715557                                                           17    4312
XP_006715555                                                           17    4312
XP_006715554                                                           17    4312
XP_006715553                                                           17    4312
XP_006715552                                                           17    4312
XP_005267054                                                           17    4312
XP_005267053                                                           17    4312
XP_006715551                                                           17    4312
XP_006715550                                                           17    4312
XP_006715549                                                           17    4312
XP_006715548                                                           17    4312
XP_006715547                                                           17    4312
XP_006715546                                                           17    4312
NP_004295                                                              16    5631
NP_112191                                                              16    5631
XP_005270251                                                           16    5631
XP_005270250                                                           16    5631
NP_002629                                                              16    5631
NP_061832                                                              16    7355
NP_733829                                                              16    7355
NP_065876                                                              16    7355
XP_006723888                                                           16    7355
XP_005259589                                                           16    7355
XP_005259588                                                           16    7355
XP_005259587                                                           16    7355
NP_004159                                                              15    9605
NP_000543                                                              15    9605
NP_001651                                                              15    9605
NP_001772                                                              15    9605
NP_060132                                                              15    9605
NP_940905                                                              15    9605
NP_001274748                                                           15    9605
NP_001274749                                                           15    9605
NP_001170781                                                           15    9605
NP_002130                                                              15    9605
XP_006717022                                                           15    9605
XP_005248388                                                           15    9605
XP_005248386                                                           15    9605
XP_006711360                                                           15    9605
XP_006711359                                                           15    9605
XP_006711358                                                           15    9605
XP_006711357                                                           15    9605
NP_001170782                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NVSGQDKIG 9
           NVSGQD+IG
Sbjct: 286 NVSGQDRIG 294
>NP_055903
          Length = 1723

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NVSGQDKIG 9
           NVSGQD+IG
Sbjct: 286 NVSGQDRIG 294
>NP_009124
          Length = 324

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVSGQDKI 8
           N+SGQD +
Sbjct: 216 NISGQDMV 223
>XP_006714136
          Length = 347

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVSGQDKI 8
           N+SGQD +
Sbjct: 239 NISGQDMV 246
>NP_001654
          Length = 175

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 63 DVGGQDKI 70
>NP_001019398
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>NP_001019397
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>NP_001019399
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>NP_001650
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>NP_001649
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>NP_001035089
          Length = 1651

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1028 AGQDKLG 1034
>NP_001193937
          Length = 1743

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1012 AGQDKLG 1018
>NP_001653
          Length = 180

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>XP_006719454
          Length = 137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>XP_005268913
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDKI
Sbjct: 67 DVGGQDKI 74
>XP_006715557
          Length = 1744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1012 AGQDKLG 1018
>XP_006715555
          Length = 1638

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1036 AGQDKLG 1042
>XP_006715554
          Length = 1768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1036 AGQDKLG 1042
>XP_006715553
          Length = 1808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1012 AGQDKLG 1018
>XP_006715552
          Length = 1817

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1021 AGQDKLG 1027
>XP_005267054
          Length = 1823

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1029 AGQDKLG 1035
>XP_005267053
          Length = 1824

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1028 AGQDKLG 1034
>XP_006715551
          Length = 1825

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1029 AGQDKLG 1035
>XP_006715550
          Length = 1830

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1036 AGQDKLG 1042
>XP_006715549
          Length = 1830

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1034 AGQDKLG 1040
>XP_006715548
          Length = 1831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1035 AGQDKLG 1041
>XP_006715547
          Length = 1831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1035 AGQDKLG 1041
>XP_006715546
          Length = 1832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SGQDKIG 9
            +GQDK+G
Sbjct: 1036 AGQDKLG 1042
>NP_004295
          Length = 1620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VSGQDKI 8
           +SG+DKI
Sbjct: 638 ISGEDKI 644
>NP_112191
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQDKI 8
           NV+GQD I
Sbjct: 183 NVTGQDVI 190
>XP_005270251
          Length = 230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQDKI 8
           NV+GQD I
Sbjct: 183 NVTGQDVI 190
>XP_005270250
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NVSGQDKI 8
           NV+GQD I
Sbjct: 183 NVTGQDVI 190
>NP_002629
          Length = 117

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQDK+
Sbjct: 52 SVKGQDKV 59
>NP_061832
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NVSGQDKIG 9
          N SG D+IG
Sbjct: 2  NNSGADEIG 10
>NP_733829
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NVSGQDKIG 9
          N SG D+IG
Sbjct: 2  NNSGADEIG 10
>NP_065876
          Length = 1269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    VSGQDKIG 9
            +SGQD  G
Sbjct: 993  ISGQDSTG 1000
>XP_006723888
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NVSGQDKIG 9
           NVS ++KIG
Sbjct: 596 NVSVREKIG 604
>XP_005259589
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NVSGQDKIG 9
          N SG D+IG
Sbjct: 2  NNSGADEIG 10
>XP_005259588
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NVSGQDKIG 9
          N SG D+IG
Sbjct: 2  NNSGADEIG 10
>XP_005259587
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NVSGQDKIG 9
          N SG D+IG
Sbjct: 2  NNSGADEIG 10
>NP_004159
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NVSGQDKI 8
           +V+GQD+I
Sbjct: 424 HVNGQDQI 431
>NP_000543
          Length = 2813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    VSGQDKIG 9
            + G DKIG
Sbjct: 1503 LEGSDKIG 1510
>NP_001651
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  NVSGQDKI 8
          +V GQD+I
Sbjct: 67 DVGGQDRI 74
>NP_001772
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NVSGQDK 7
           NV+G DK
Sbjct: 166 NVTGSDK 172
>NP_060132
          Length = 2022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NVSGQDKIG 9
            N+SG  +IG
Sbjct: 1558 NLSGSSEIG 1566
>NP_940905
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    NVSGQD 6
            NV+GQD
Sbjct: 1123 NVTGQD 1128
>NP_001274748
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    NVSGQD 6
            NV+GQD
Sbjct: 1099 NVTGQD 1104
>NP_001274749
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    NVSGQD 6
            NV+GQD
Sbjct: 1056 NVTGQD 1061
>NP_001170781
          Length = 2017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NVSGQDKIG 9
            N+SG  +IG
Sbjct: 1553 NLSGSSEIG 1561
>NP_002130
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SGQDKIG 9
           SG+D++G
Sbjct: 337 SGRDRVG 343
>XP_006717022
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NVSGQDKIG 9
           N+SG  +IG
Sbjct: 590 NLSGSSEIG 598
>XP_005248388
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NVSGQDKI 8
           +V+GQD+I
Sbjct: 424 HVNGQDQI 431
>XP_005248386
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NVSGQDKI 8
           +V+GQD+I
Sbjct: 424 HVNGQDQI 431
>XP_006711360
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQD 6
           NV+GQD
Sbjct: 687 NVTGQD 692
>XP_006711359
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVSGQD 6
           NV+GQD
Sbjct: 740 NVTGQD 745
>XP_006711358
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    NVSGQD 6
            NV+GQD
Sbjct: 1106 NVTGQD 1111
>XP_006711357
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    NVSGQD 6
            NV+GQD
Sbjct: 1130 NVTGQD 1135
>NP_001170782
          Length = 2017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NVSGQDKIG 9
            N+SG  +IG
Sbjct: 1553 NLSGSSEIG 1561
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.132    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 629,096
Number of extensions: 927
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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