Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005256795                                                           17    4312
NP_002887                                                              16    5631
NP_001070143                                                           16    5631
NP_660340                                                              16    5631
NP_113680                                                              16    5631
NP_001185774                                                           16    5631
NP_001157819                                                           16    7355
NP_001157814                                                           16    7355
NP_001157816                                                           16    7355
NP_056457                                                              16    7355
NP_001157817                                                           16    7355
NP_001157815                                                           16    7355
NP_001157818                                                           16    7355
NP_001171313                                                           16    7355
NP_003130                                                              16    7355
NP_005550                                                              16    7355
XP_005259613                                                           16    7355
XP_005262993                                                           16    7355
XP_005262994                                                           16    7355
XP_005247400                                                           16    7355
XP_005247399                                                           16    7355
XP_006713644                                                           16    7355
XP_006713643                                                           16    7355
XP_006713642                                                           16    7355
XP_005247398                                                           16    7355
XP_005247397                                                           16    7355
XP_005247396                                                           16    7355
XP_006713641                                                           16    7355
XP_006713640                                                           16    7355
NP_001033793                                                           16    7355
NP_938022                                                              16    7355
NP_060103                                                              15    9605
NP_001364                                                              15    9605
NP_848605                                                              15    9605
NP_001129120                                                           15    9605
NP_006834                                                              15    9605
NP_002835                                                              15    9605
NP_060350                                                              15    9605
NP_001032238                                                           15    9605
NP_006812                                                              15    9605
XP_006725089                                                           15    9605
XP_006725088                                                           15    9605
XP_006725087                                                           15    9605
XP_006725086                                                           15    9605
XP_006725085                                                           15    9605
XP_006725084                                                           15    9605
XP_006725083                                                           15    9605
XP_006725082                                                           15    9605
XP_006718873                                                           15    9605
XP_006718872                                                           15    9605
XP_006715604                                                           15    9605
XP_006715603                                                           15    9605
XP_005267143                                                           15    9605
XP_006715602                                                           15    9605
XP_006715601                                                           15    9605
XP_005267142                                                           15    9605
XP_006715600                                                           15    9605
XP_005267139                                                           15    9605
XP_006715599                                                           15    9605
XP_006715598                                                           15    9605
XP_005264448                                                           15    9605
XP_005264447                                                           15    9605
XP_005264446                                                           15    9605
XP_006711798                                                           15    9605
NP_443175                                                              15    9605
NP_002535                                                              15    9605
>XP_005256795
          Length = 294

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RTPLTM 8
           RTPLTM
Sbjct: 245 RTPLTM 250
>NP_002887
          Length = 364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VRTPLTM 8
           VRTP TM
Sbjct: 197 VRTPYTM 203
>NP_001070143
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  RTPLTMK 9
          R PLTMK
Sbjct: 60 RKPLTMK 66
>NP_660340
          Length = 92

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  RTPLTMK 9
          R PLTMK
Sbjct: 60 RKPLTMK 66
>NP_113680
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VRTPLTM 8
           VRTP TM
Sbjct: 197 VRTPYTM 203
>NP_001185774
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VRTPLTM 8
           VRTP TM
Sbjct: 172 VRTPYTM 178
>NP_001157819
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>NP_001157814
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 486 NLRMPLTL 493
>NP_001157816
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>NP_056457
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>NP_001157817
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>NP_001157815
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>NP_001157818
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>NP_001171313
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VRTPLTMK 9
           +R P TMK
Sbjct: 102 IRAPTTMK 109
>NP_003130
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VRTPLTMK 9
           +R P TMK
Sbjct: 130 IRAPTTMK 137
>NP_005550
          Length = 3075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    VRTPLTM 8
            VRTP+T+
Sbjct: 1166 VRTPVTL 1172
>XP_005259613
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  NVRTPLT 7
          +VRTP+T
Sbjct: 17 HVRTPMT 23
>XP_005262993
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VRTPLTM 8
           + TPLTM
Sbjct: 122 IHTPLTM 128
>XP_005262994
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VRTPLTM 8
           + TPLTM
Sbjct: 122 IHTPLTM 128
>XP_005247400
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>XP_005247399
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>XP_006713644
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>XP_006713643
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 413 NLRMPLTL 420
>XP_006713642
          Length = 685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 430 NLRMPLTL 437
>XP_005247398
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 486 NLRMPLTL 493
>XP_005247397
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 486 NLRMPLTL 493
>XP_005247396
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 486 NLRMPLTL 493
>XP_006713641
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 486 NLRMPLTL 493
>XP_006713640
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NVRTPLTM 8
           N+R PLT+
Sbjct: 486 NLRMPLTL 493
>NP_001033793
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVRTPL 6
           NVRTP+
Sbjct: 320 NVRTPI 325
>NP_938022
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VRTPLTM 8
           + TPLTM
Sbjct: 122 IHTPLTM 128
>NP_060103
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TPLTMK 9
           TPLT+K
Sbjct: 179 TPLTLK 184
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    NVRTPLTM 8
            N RTPL +
Sbjct: 3821 NARTPLIL 3828
>NP_848605
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVRTPL 6
           N+RTPL
Sbjct: 526 NLRTPL 531
>NP_001129120
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>NP_006834
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVRTPL 6
           N+RTPL
Sbjct: 290 NLRTPL 295
>NP_002835
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>NP_060350
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TPLTMK 9
           TPLT+K
Sbjct: 147 TPLTLK 152
>NP_001032238
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVRTPLTMK 9
           +VRTPL ++
Sbjct: 97  DVRTPLAVE 105
>NP_006812
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NVRTPLTMK 9
           +VRTPL ++
Sbjct: 159 DVRTPLAVE 167
>XP_006725089
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006725088
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006725087
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006725086
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2 VRTPLTMK 9
         +RTP T+K
Sbjct: 1 MRTPKTLK 8
>XP_006725085
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 319 MRTPKTLK 326
>XP_006725084
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 319 MRTPKTLK 326
>XP_006725083
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006725082
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006718873
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVRTPL 6
           N+RTPL
Sbjct: 357 NLRTPL 362
>XP_006718872
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVRTPL 6
           N+RTPL
Sbjct: 478 NLRTPL 483
>XP_006715604
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006715603
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_005267143
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006715602
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006715601
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2 VRTPLTMK 9
         +RTP T+K
Sbjct: 1 MRTPKTLK 8
>XP_005267142
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006715600
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_005267139
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006715599
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_006715598
          Length = 1470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTPLTMK 9
           +RTP T+K
Sbjct: 390 MRTPKTLK 397
>XP_005264448
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TPLTMK 9
           TPLT+K
Sbjct: 147 TPLTLK 152
>XP_005264447
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TPLTMK 9
           TPLT+K
Sbjct: 147 TPLTLK 152
>XP_005264446
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TPLTMK 9
           TPLT+K
Sbjct: 147 TPLTLK 152
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    NVRTPLTM 8
            N RTPL +
Sbjct: 3883 NARTPLIL 3890
>NP_443175
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TPLTMK 9
           TPLT+K
Sbjct: 165 TPLTLK 170
>NP_002535
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NVRTPL 6
           NV+TPL
Sbjct: 410 NVKTPL 415
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.127    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 636,862
Number of extensions: 868
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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