Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_006714104                                                           19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
NP_066925                                                              18    1935
NP_001159575                                                           18    1935
NP_004229                                                              17    3301
NP_001271144                                                           17    3301
NP_001271143                                                           17    3301
NP_001271145                                                           17    3301
XP_006712916                                                           17    3301
XP_005247020                                                           17    3301
XP_005247019                                                           17    3301
XP_006712915                                                           17    3301
XP_005247018                                                           17    3301
XP_005247017                                                           17    3301
XP_005247015                                                           17    3301
XP_005247014                                                           17    3301
XP_005247013                                                           17    3301
XP_005247012                                                           17    3301
XP_005247011                                                           17    3301
NP_001073296                                                           17    3301
NP_001265088                                                           17    4312
NP_001092102                                                           17    4312
NP_115751                                                              17    4312
NP_001092103                                                           17    4312
NP_001265089                                                           17    4312
NP_115553                                                              16    5631
NP_619642                                                              16    7355
NP_803884                                                              16    7355
NP_001229269                                                           16    7355
NP_776168                                                              16    7355
NP_001124429                                                           16    7355
NP_056382                                                              16    7355
XP_005254096                                                           16    7355
XP_005254095                                                           16    7355
XP_005268519                                                           16    7355
XP_006714849                                                           16    7355
XP_005268518                                                           16    7355
XP_006711820                                                           16    7355
XP_005273147                                                           16    7355
XP_006711819                                                           16    7355
XP_005245315                                                           16    7355
XP_006711447                                                           16    7355
XP_005245314                                                           16    7355
NP_057547                                                              16    7355
NP_002637                                                              16    7355
NP_002045                                                              15    9605
NP_015628                                                              15    9605
NP_543009                                                              15    9605
NP_001072980                                                           15    9605
NP_002636                                                              15    9605
XP_006721007                                                           15    9605
XP_005255620                                                           15    9605
XP_005253037                                                           15    9605
XP_005253036                                                           15    9605
XP_005253035                                                           15    9605
XP_005253034                                                           15    9605
XP_006718048                                                           15    9605
XP_006716574                                                           15    9605
NP_001137230                                                           15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NSGLFVMVL 9
          NSGLFV VL
Sbjct: 77 NSGLFVTVL 85
>XP_006714104
          Length = 832

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           NSGLFV VL
Sbjct: 102 NSGLFVTVL 110
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NSGLFVMVL 9
          NSGLFV VL
Sbjct: 77 NSGLFVTVL 85
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           NSGLFV VL
Sbjct: 99  NSGLFVTVL 107
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           NSGLFV VL
Sbjct: 102 NSGLFVTVL 110
>NP_066925
          Length = 252

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGLFVMVL 9
           +GLFVMVL
Sbjct: 202 AGLFVMVL 209
>NP_001159575
          Length = 195

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGLFVMVL 9
           +GLFVMVL
Sbjct: 145 AGLFVMVL 152
>NP_004229
          Length = 1992

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 664 SSGMFIMVV 672
>NP_001271144
          Length = 2025

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 670 SSGMFIMVV 678
>NP_001271143
          Length = 2040

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>NP_001271145
          Length = 1722

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 367 SSGMFIMVV 375
>XP_006712916
          Length = 1998

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 670 SSGMFIMVV 678
>XP_005247020
          Length = 2013

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>XP_005247019
          Length = 2025

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 670 SSGMFIMVV 678
>XP_006712915
          Length = 2026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 670 SSGMFIMVV 678
>XP_005247018
          Length = 2026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 670 SSGMFIMVV 678
>XP_005247017
          Length = 2039

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 683 SSGMFIMVV 691
>XP_005247015
          Length = 2041

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>XP_005247014
          Length = 2063

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>XP_005247013
          Length = 2067

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>XP_005247012
          Length = 2068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>XP_005247011
          Length = 2068

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NSGLFVMVL 9
           +SG+F+MV+
Sbjct: 712 SSGMFIMVV 720
>NP_001073296
          Length = 232

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           N+GL VM+L
Sbjct: 94  NAGLHVMIL 102
>NP_001265088
          Length = 256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLFVM
Sbjct: 125 NGGLFVM 131
>NP_001092102
          Length = 256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLFVM
Sbjct: 125 NGGLFVM 131
>NP_115751
          Length = 276

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLFVM
Sbjct: 145 NGGLFVM 151
>NP_001092103
          Length = 256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLFVM
Sbjct: 125 NGGLFVM 131
>NP_001265089
          Length = 256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLFVM
Sbjct: 125 NGGLFVM 131
>NP_115553
          Length = 394

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLF+M
Sbjct: 271 NGGLFIM 277
>NP_619642
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SGLFVMV 8
           +GLFVM+
Sbjct: 679 AGLFVMI 685
>NP_803884
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SGLFVMV 8
           +GLFVM+
Sbjct: 425 AGLFVMI 431
>NP_001229269
          Length = 800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSGLFVMV 8
           N+GL+V+V
Sbjct: 465 NTGLYVIV 472
>NP_776168
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSGLFVMV 8
           N+GL+V+V
Sbjct: 616 NTGLYVIV 623
>NP_001124429
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSGLFVMV 8
           N+GL+V+V
Sbjct: 616 NTGLYVIV 623
>NP_056382
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SGLFVMVL 9
           +GLFV+V+
Sbjct: 682 AGLFVLVM 689
>XP_005254096
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SGLFVMVL 9
           +GLFV+V+
Sbjct: 682 AGLFVLVM 689
>XP_005254095
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SGLFVMVL 9
           +GLFV+V+
Sbjct: 682 AGLFVLVM 689
>XP_005268519
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLF+M
Sbjct: 217 NPGLFIM 223
>XP_006714849
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLF+M
Sbjct: 217 NPGLFIM 223
>XP_005268518
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLF+M
Sbjct: 217 NPGLFIM 223
>XP_006711820
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSGLFVMV 8
           N+GL+V+V
Sbjct: 474 NTGLYVIV 481
>XP_005273147
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSGLFVMV 8
           N+GL+V+V
Sbjct: 474 NTGLYVIV 481
>XP_006711819
          Length = 884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NSGLFVMV 8
           N+GL+V+V
Sbjct: 549 NTGLYVIV 556
>XP_005245315
          Length = 1607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSGLFVMVL 9
            N+ LF+MV+
Sbjct: 1489 NNKLFIMVM 1497
>XP_006711447
          Length = 1634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSGLFVMVL 9
            N+ LF+MV+
Sbjct: 1516 NNKLFIMVM 1524
>XP_005245314
          Length = 1634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSGLFVMVL 9
            N+ LF+MV+
Sbjct: 1516 NNKLFIMVM 1524
>NP_057547
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NSGLFVM 7
           N GLF+M
Sbjct: 217 NPGLFIM 223
>NP_002637
          Length = 1634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSGLFVMVL 9
            N+ LF+MV+
Sbjct: 1516 NNKLFIMVM 1524
>NP_002045
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SGLFVMVL 9
          +GLFVM++
Sbjct: 8  AGLFVMLV 15
>NP_015628
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           N G+F+++L
Sbjct: 855 NCGIFIVML 863
>NP_543009
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SGLFVMVL 9
          +GL VMVL
Sbjct: 9  AGLLVMVL 16
>NP_001072980
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  GLFVMVL 9
          G FVMVL
Sbjct: 61 GCFVMVL 67
>NP_002636
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NSGLFVMVL 9
            N  LF+MV+
Sbjct: 1571 NGTLFIMVM 1579
>XP_006721007
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  GLFVMVL 9
          G FVMVL
Sbjct: 61 GCFVMVL 67
>XP_005255620
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  GLFVMVL 9
          G FVMVL
Sbjct: 61 GCFVMVL 67
>XP_005253037
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NSGLFVMVL 9
            N  LF+MV+
Sbjct: 1191 NGTLFIMVM 1199
>XP_005253036
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NSGLFVMVL 9
            N  LF+MV+
Sbjct: 1571 NGTLFIMVM 1579
>XP_005253035
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NSGLFVMVL 9
            N  LF+MV+
Sbjct: 1571 NGTLFIMVM 1579
>XP_005253034
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NSGLFVMVL 9
            N  LF+MV+
Sbjct: 1571 NGTLFIMVM 1579
>XP_006718048
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           +SG F++VL
Sbjct: 366 SSGRFILVL 374
>XP_006716574
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NSGLFV 6
           NSG+FV
Sbjct: 940 NSGIFV 945
>NP_001137230
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NSGLFVMVL 9
           +SG F++VL
Sbjct: 374 SSGRFILVL 382
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.149    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 389,252
Number of extensions: 384
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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