Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              21     229
NP_004629                                                              18    1935
NP_542417                                                              18    1935
XP_006726175                                                           18    1935
XP_006726174                                                           18    1935
XP_006726087                                                           18    1935
XP_006726086                                                           18    1935
XP_006725985                                                           18    1935
XP_006725897                                                           18    1935
XP_006725896                                                           18    1935
XP_006725787                                                           18    1935
XP_006725786                                                           18    1935
XP_006725571                                                           18    1935
XP_006725570                                                           18    1935
XP_006715254                                                           18    1935
NP_064548                                                              17    4312
XP_005265384                                                           17    4312
NP_036442                                                              16    5631
XP_005254225                                                           16    5631
NP_689666                                                              16    5631
NP_001229687                                                           16    5631
NP_001243718                                                           16    7355
NP_001243719                                                           16    7355
NP_005174                                                              16    7355
NP_055987                                                              16    7355
NP_116242                                                              16    7355
XP_005245087                                                           16    7355
XP_005245086                                                           16    7355
XP_005245085                                                           16    7355
XP_005245084                                                           16    7355
XP_006711302                                                           16    7355
XP_005245083                                                           16    7355
XP_005245082                                                           16    7355
XP_005245081                                                           16    7355
XP_005245080                                                           16    7355
XP_005245079                                                           16    7355
XP_005245077                                                           16    7355
XP_005245076                                                           16    7355
XP_006711301                                                           16    7355
XP_005245075                                                           16    7355
XP_005245074                                                           16    7355
XP_005245073                                                           16    7355
XP_005245072                                                           16    7355
NP_002323                                                              15    9605
NP_005451                                                              15    9605
NP_000612                                                              15    9605
NP_001159419                                                           15    9605
NP_116167                                                              15    9605
NP_694822                                                              15    9605
NP_001035998                                                           15    9605
NP_001248758                                                           15    9605
NP_919226                                                              15    9605
NP_001269901                                                           15    9605
NP_057609                                                              15    9605
NP_001028222                                                           15    9605
NP_001164674                                                           15    9605
NP_079474                                                              15    9605
NP_001164675                                                           15    9605
NP_055690                                                              15    9605
NP_001164673                                                           15    9605
XP_006719676                                                           15    9605
XP_006719675                                                           15    9605
XP_006716842                                                           15    9605
XP_006714798                                                           15    9605
XP_006714797                                                           15    9605
XP_005272195                                                           15    9605
XP_005272196                                                           15    9605
XP_005247895                                                           15    9605
XP_006712610                                                           15    9605
XP_006712609                                                           15    9605
NP_001164672                                                           15    9605
NP_057645                                                              15    9605
NP_001017415                                                           15    9605
NP_003359                                                              15    9605
NP_001017416                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NSDQANQKM 9
           NSDQANQ+M
Sbjct: 563 NSDQANQQM 571
>NP_004629
          Length = 2157

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>NP_542417
          Length = 2157

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>XP_006726175
          Length = 2086

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>XP_006726174
          Length = 2156

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1312 NSDQANEE 1319
>XP_006726087
          Length = 2086

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>XP_006726086
          Length = 2156

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1312 NSDQANEE 1319
>XP_006725985
          Length = 2156

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1312 NSDQANEE 1319
>XP_006725897
          Length = 2086

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>XP_006725896
          Length = 2156

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1312 NSDQANEE 1319
>XP_006725787
          Length = 2086

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>XP_006725786
          Length = 2156

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1312 NSDQANEE 1319
>XP_006725571
          Length = 2086

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>XP_006725570
          Length = 2156

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1312 NSDQANEE 1319
>XP_006715254
          Length = 2086

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            NSDQAN++
Sbjct: 1313 NSDQANEE 1320
>NP_064548
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           NSDQ N K+
Sbjct: 235 NSDQDNDKV 243
>XP_005265384
          Length = 564

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           NSDQ N K+
Sbjct: 253 NSDQDNDKV 261
>NP_036442
          Length = 1232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SDQANQKM 9
           ++QAN+KM
Sbjct: 423 TEQANEKM 430
>XP_005254225
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  DQANQKM 9
          D+ANQK+
Sbjct: 28 DEANQKL 34
>NP_689666
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  DQANQKM 9
          D+ANQK+
Sbjct: 28 DEANQKL 34
>NP_001229687
          Length = 365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NSDQANQKM 9
          +SD A+QKM
Sbjct: 61 DSDAASQKM 69
>NP_001243718
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSDQANQKM 9
            N +QANQ++
Sbjct: 1531 NLEQANQEL 1539
>NP_001243719
          Length = 1912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSDQANQKM 9
            N +QANQ++
Sbjct: 1477 NLEQANQEL 1485
>NP_005174
          Length = 1977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NSDQANQKM 9
            N +QANQ++
Sbjct: 1542 NLEQANQEL 1550
>NP_055987
          Length = 2817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1488 SSDQANEE 1495
>NP_116242
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DQANQKM 9
           D+ANQK+
Sbjct: 570 DRANQKL 576
>XP_005245087
          Length = 2708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245086
          Length = 2714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245085
          Length = 2718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245084
          Length = 2719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_006711302
          Length = 2754

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245083
          Length = 2774

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245082
          Length = 2779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245081
          Length = 2819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245080
          Length = 2824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245079
          Length = 2838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245077
          Length = 2858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245076
          Length = 2869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_006711301
          Length = 2896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1488 SSDQANEE 1495
>XP_005245075
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1485 SSDQANEE 1492
>XP_005245074
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>XP_005245073
          Length = 2901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1488 SSDQANEE 1495
>XP_005245072
          Length = 2903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NSDQANQK 8
            +SDQAN++
Sbjct: 1490 SSDQANEE 1497
>NP_002323
          Length = 4544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    NSDQAN 6
            NSD+AN
Sbjct: 3402 NSDEAN 3407
>NP_005451
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           + DQ NQK+
Sbjct: 94  SDDQKNQKV 102
>NP_000612
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           NSD  N+K+
Sbjct: 460 NSDGVNEKV 468
>NP_001159419
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           NSD  N+K+
Sbjct: 376 NSDGVNEKV 384
>NP_116167
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDQANQKM 9
           SD+A +KM
Sbjct: 382 SDEAQEKM 389
>NP_694822
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDQANQKM 9
           SD+A +KM
Sbjct: 383 SDEAQEKM 390
>NP_001035998
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDQANQKM 9
           SD+A +KM
Sbjct: 383 SDEAQEKM 390
>NP_001248758
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDQANQKM 9
           SD+A +KM
Sbjct: 382 SDEAQEKM 389
>NP_919226
          Length = 1209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NSDQANQ 7
           NS+Q NQ
Sbjct: 868 NSEQTNQ 874
>NP_001269901
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  DQANQKM 9
          D+A+QKM
Sbjct: 30 DEASQKM 36
>NP_057609
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSDQANQK 8
           +SD +NQK
Sbjct: 272 DSDDSNQK 279
>NP_001028222
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DQANQKM 9
           DQ NQK+
Sbjct: 145 DQENQKL 151
>NP_001164674
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSDQANQK 8
           +SD +NQK
Sbjct: 272 DSDDSNQK 279
>NP_079474
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DQANQKM 9
           DQ NQK+
Sbjct: 145 DQENQKL 151
>NP_001164675
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSDQANQK 8
           +SD +NQK
Sbjct: 272 DSDDSNQK 279
>NP_055690
          Length = 1648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SDQANQK 8
           S+QANQ+
Sbjct: 641 SEQANQR 647
>NP_001164673
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSDQANQK 8
           +SD +NQK
Sbjct: 308 DSDDSNQK 315
>XP_006719676
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DQANQKM 9
           DQ NQK+
Sbjct: 145 DQENQKL 151
>XP_006719675
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DQANQKM 9
           DQ NQK+
Sbjct: 145 DQENQKL 151
>XP_006716842
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSDQANQK 8
           +SD +NQK
Sbjct: 272 DSDDSNQK 279
>XP_006714798
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           + DQ NQK+
Sbjct: 94  SDDQKNQKV 102
>XP_006714797
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           + DQ NQK+
Sbjct: 94  SDDQKNQKV 102
>XP_005272195
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           + DQ NQK+
Sbjct: 94  SDDQKNQKV 102
>XP_005272196
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NSDQANQKM 9
           + DQ NQK+
Sbjct: 94  SDDQKNQKV 102
>XP_005247895
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SDQANQKM 9
           SD+A +KM
Sbjct: 383 SDEAQEKM 390
>XP_006712610
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  DQANQKM 9
          D+A+QKM
Sbjct: 57 DEASQKM 63
>XP_006712609
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  DQANQKM 9
          D+A+QKM
Sbjct: 62 DEASQKM 68
>NP_001164672
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSDQANQK 8
           +SD +NQK
Sbjct: 336 DSDDSNQK 343
>NP_057645
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NSDQANQKM 9
           N+ +ANQ+M
Sbjct: 132 NTGRANQQM 140
>NP_001017415
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DQANQK 8
           D+ANQK
Sbjct: 125 DEANQK 130
>NP_003359
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DQANQK 8
           D+ANQK
Sbjct: 125 DEANQK 130
>NP_001017416
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DQANQK 8
           D+ANQK
Sbjct: 125 DEANQK 130
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290    0.100    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 494,719
Number of extensions: 1069
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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