Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     509
NP_653080                                                              20     509
XP_005267292                                                           20     509
XP_005267291                                                           20     509
XP_005267290                                                           20     509
NP_001116151                                                           17    4312
XP_006714960                                                           17    4312
XP_005266007                                                           17    4312
NP_001073946                                                           16    5631
NP_060896                                                              16    5631
NP_001265546                                                           16    5631
NP_001265545                                                           16    5631
NP_004327                                                              16    5631
XP_005249274                                                           16    5631
XP_005249273                                                           16    5631
XP_005249272                                                           16    5631
XP_005249271                                                           16    5631
XP_006715198                                                           16    5631
XP_005249269                                                           16    5631
XP_005249270                                                           16    5631
XP_005249268                                                           16    5631
XP_006714321                                                           16    5631
XP_006714320                                                           16    5631
XP_006714319                                                           16    5631
NP_775762                                                              16    5631
NP_055880                                                              16    7355
NP_001185885                                                           16    7355
NP_001185886                                                           16    7355
NP_060912                                                              16    7355
NP_001017977                                                           16    7355
NP_001158238                                                           16    7355
NP_001136271                                                           16    7355
NP_008816                                                              16    7355
NP_001136270                                                           16    7355
XP_005256014                                                           16    7355
XP_005271520                                                           16    7355
XP_005271519                                                           16    7355
XP_005271518                                                           16    7355
XP_005245390                                                           16    7355
XP_005245389                                                           16    7355
XP_005245388                                                           16    7355
NP_777553                                                              16    7355
NP_001186091                                                           15    9605
NP_001186090                                                           15    9605
NP_006668                                                              15    9605
NP_001186089                                                           15    9605
NP_055268                                                              15    9605
NP_940818                                                              15    9605
NP_003239                                                              15    9605
XP_005258804                                                           15    9605
XP_005258803                                                           15    9605
XP_005264888                                                           15    9605
XP_006713016                                                           15    9605
XP_005264887                                                           15    9605
XP_006713015                                                           15    9605
XP_006713014                                                           15    9605
XP_006713013                                                           15    9605
XP_006713012                                                           15    9605
XP_006713011                                                           15    9605
XP_005264886                                                           15    9605
XP_006713010                                                           15    9605
XP_005264885                                                           15    9605
XP_005264884                                                           15    9605
XP_005264883                                                           15    9605
XP_005264882                                                           15    9605
XP_006713009                                                           15    9605
XP_005264881                                                           15    9605
XP_005264880                                                           15    9605
>NP_005091
          Length = 1782

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NSALTDTDA 9
            NSAL DTDA
Sbjct: 1711 NSALADTDA 1719
>NP_653080
          Length = 1684

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NSALTDTDA 9
            NSAL DTDA
Sbjct: 1613 NSALADTDA 1621
>XP_005267292
          Length = 1677

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NSALTDTDA 9
            NSAL DTDA
Sbjct: 1606 NSALADTDA 1614
>XP_005267291
          Length = 1684

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NSALTDTDA 9
            NSAL DTDA
Sbjct: 1613 NSALADTDA 1621
>XP_005267290
          Length = 1782

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NSALTDTDA 9
            NSAL DTDA
Sbjct: 1711 NSALADTDA 1719
>NP_001116151
          Length = 2765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   NSALTDTDA 9
           NSALT TD+
Sbjct: 149 NSALTLTDS 157
>XP_006714960
          Length = 2758

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   NSALTDTDA 9
           NSALT TD+
Sbjct: 149 NSALTLTDS 157
>XP_005266007
          Length = 2765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   NSALTDTDA 9
           NSALT TD+
Sbjct: 149 NSALTLTDS 157
>NP_001073946
          Length = 2699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           NSALT TD
Sbjct: 152 NSALTLTD 159
>NP_060896
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 812 ALTDTD 817
>NP_001265546
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LTDTDA 9
           LTDTDA
Sbjct: 700 LTDTDA 705
>NP_001265545
          Length = 1065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LTDTDA 9
           LTDTDA
Sbjct: 680 LTDTDA 685
>NP_004327
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LTDTDA 9
           LTDTDA
Sbjct: 700 LTDTDA 705
>XP_005249274
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249273
          Length = 814

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 794 ALTDTD 799
>XP_005249272
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 799 ALTDTD 804
>XP_005249271
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 808 ALTDTD 813
>XP_006715198
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249269
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249270
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249268
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALTDTD 8
           ALTDTD
Sbjct: 821 ALTDTD 826
>XP_006714321
          Length = 2713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           NSALT TD
Sbjct: 152 NSALTLTD 159
>XP_006714320
          Length = 2720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           NSALT TD
Sbjct: 152 NSALTLTD 159
>XP_006714319
          Length = 2721

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           NSALT TD
Sbjct: 152 NSALTLTD 159
>NP_775762
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NSALTDTD 8
           N ALTD D
Sbjct: 195 NMALTDVD 202
>NP_055880
          Length = 1989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NSALTDT 7
           +SALTDT
Sbjct: 850 SSALTDT 856
>NP_001185885
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 725 DSALQDTD 732
>NP_001185886
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 694 DSALQDTD 701
>NP_060912
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 668 DSALQDTD 675
>NP_001017977
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 648 DSALQDTD 655
>NP_001158238
          Length = 2789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSALTDT 7
            N+A+TDT
Sbjct: 1925 NTAITDT 1931
>NP_001136271
          Length = 138

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SALTDTDA 9
           SAL D+DA
Sbjct: 107 SALNDSDA 114
>NP_008816
          Length = 3703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSALTDT 7
            N+A+TDT
Sbjct: 2839 NTAITDT 2845
>NP_001136270
          Length = 192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SALTDTDA 9
           SAL D+DA
Sbjct: 141 SALNDSDA 148
>XP_005256014
          Length = 3702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    NSALTDT 7
            N+A+TDT
Sbjct: 2838 NTAITDT 2844
>XP_005271520
          Length = 1801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NSALTDT 7
           +SALTDT
Sbjct: 662 SSALTDT 668
>XP_005271519
          Length = 1833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NSALTDT 7
           +SALTDT
Sbjct: 694 SSALTDT 700
>XP_005271518
          Length = 1982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NSALTDT 7
           +SALTDT
Sbjct: 843 SSALTDT 849
>XP_005245390
          Length = 874

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 648 DSALQDTD 655
>XP_005245389
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 668 DSALQDTD 675
>XP_005245388
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           +SAL DTD
Sbjct: 725 DSALQDTD 732
>NP_777553
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SALTDTDA 9
           SAL D+DA
Sbjct: 141 SALNDSDA 148
>NP_001186091
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>NP_001186090
          Length = 1384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>NP_006668
          Length = 1318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>NP_001186089
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>NP_055268
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SALTDTDA 9
           SAL D DA
Sbjct: 203 SALADADA 210
>NP_940818
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SALTDTDA 9
           SAL D DA
Sbjct: 203 SALADADA 210
>NP_003239
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NSALTDTD 8
           NSA  DTD
Sbjct: 648 NSAQLDTD 655
>XP_005258804
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SALTDTDA 9
           SAL D DA
Sbjct: 246 SALADADA 253
>XP_005258803
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SALTDTDA 9
           SAL D DA
Sbjct: 246 SALADADA 253
>XP_005264888
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_006713016
          Length = 1404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_005264887
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_006713015
          Length = 1367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_006713014
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_006713013
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_006713012
          Length = 1373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_006713011
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_005264886
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_006713010
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_005264885
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_005264884
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 129 DAAFTDTD 136
>XP_005264883
          Length = 1421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_005264882
          Length = 1421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_006713009
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_005264881
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
>XP_005264880
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NSALTDTD 8
           ++A TDTD
Sbjct: 144 DAAFTDTD 151
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.106    0.263 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 485,514
Number of extensions: 715
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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