Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           19     869
NP_001138386                                                           19     869
NP_000132                                                              19     869
NP_075259                                                              19     869
NP_001138385                                                           19     869
XP_006717776                                                           19     869
XP_006717773                                                           19     869
XP_006717772                                                           19     869
XP_006717771                                                           19     869
NP_004516                                                              16    5631
XP_006712591                                                           16    5631
XP_006712590                                                           16    5631
XP_006712589                                                           16    5631
>NP_001138389
          Length = 705

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NRTVLIVEY 9
          NRTVLI EY
Sbjct: 83 NRTVLIGEY 91
>NP_001138386
          Length = 709

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NRTVLIVEY 9
          NRTVLI EY
Sbjct: 83 NRTVLIGEY 91
>NP_000132
          Length = 821

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NRTVLIVEY 9
          NRTVLI EY
Sbjct: 83 NRTVLIGEY 91
>NP_075259
          Length = 822

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NRTVLIVEY 9
          NRTVLI EY
Sbjct: 83 NRTVLIGEY 91
>NP_001138385
          Length = 769

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NRTVLIVEY 9
          NRTVLI EY
Sbjct: 83 NRTVLIGEY 91
>XP_006717776
          Length = 806

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NRTVLIVEY 9
           NRTVLI EY
Sbjct: 102 NRTVLIGEY 110
>XP_006717773
          Length = 807

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NRTVLIVEY 9
           NRTVLI EY
Sbjct: 102 NRTVLIGEY 110
>XP_006717772
          Length = 838

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NRTVLIVEY 9
           NRTVLI EY
Sbjct: 102 NRTVLIGEY 110
>XP_006717771
          Length = 839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NRTVLIVEY 9
           NRTVLI EY
Sbjct: 102 NRTVLIGEY 110
>NP_004516
          Length = 4655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NRTVLIVE 8
            NRTVL+ E
Sbjct: 2224 NRTVLVSE 2231
>XP_006712591
          Length = 3308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NRTVLIVE 8
            NRTVL+ E
Sbjct: 2229 NRTVLVSE 2236
>XP_006712590
          Length = 3897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NRTVLIVE 8
            NRTVL+ E
Sbjct: 1466 NRTVLVSE 1473
>XP_006712589
          Length = 4660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NRTVLIVE 8
            NRTVL+ E
Sbjct: 2229 NRTVLVSE 2236
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.143    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,876
Number of extensions: 445
Number of successful extensions: 13
Number of sequences better than 10000.0: 13
Number of HSP's gapped: 13
Number of HSP's successfully gapped: 13
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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