Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_919047                                                              20     509
NP_443086                                                              20     509
XP_005250598                                                           20     509
NP_060513                                                              17    2528
XP_006718666                                                           17    2528
XP_006718665                                                           17    2528
XP_006718664                                                           17    2528
XP_006718663                                                           17    2528
XP_006718662                                                           17    2528
XP_006718661                                                           17    2528
XP_006718660                                                           17    2528
XP_006718659                                                           17    2528
XP_006718658                                                           17    2528
XP_006718657                                                           17    2528
XP_006718656                                                           17    2528
NP_001271332                                                           17    3301
NP_079030                                                              17    3301
XP_005248658                                                           17    3301
NP_004989                                                              17    4312
NP_036467                                                              17    4312
NP_115766                                                              17    4312
NP_705833                                                              17    4312
XP_005272534                                                           17    4312
XP_005272533                                                           17    4312
XP_005272532                                                           17    4312
XP_006718546                                                           17    4312
XP_005247174                                                           17    4312
NP_055992                                                              17    4312
NP_079019                                                              16    5631
NP_001363                                                              16    5631
XP_006721528                                                           16    5631
NP_004653                                                              16    5631
NP_076915                                                              16    7355
NP_002445                                                              16    7355
NP_000024                                                              16    7355
NP_001269721                                                           16    7355
NP_001165415                                                           16    7355
NP_079430                                                              16    7355
XP_006721530                                                           16    7355
XP_006721529                                                           16    7355
XP_006714537                                                           16    7355
XP_005246720                                                           16    7355
NP_001035869                                                           16    7355
NP_060559                                                              16    7355
NP_001124437                                                           16    7355
NP_277052                                                              15    9605
NP_612486                                                              15    9605
NP_001157281                                                           15    9605
NP_001020016                                                           15    9605
NP_964012                                                              15    9605
NP_008865                                                              15    9605
NP_001248309                                                           15    9605
NP_001185463                                                           15    9605
NP_001185461                                                           15    9605
NP_001020774                                                           15    9605
NP_000440                                                              15    9605
NP_115682                                                              15    9605
NP_001185462                                                           15    9605
XP_006725317                                                           15    9605
XP_005259715                                                           15    9605
XP_005256511                                                           15    9605
XP_005254235                                                           15    9605
XP_005254233                                                           15    9605
XP_005254234                                                           15    9605
XP_005251053                                                           15    9605
XP_005251052                                                           15    9605
XP_005251051                                                           15    9605
XP_005251050                                                           15    9605
XP_006716657                                                           15    9605
XP_005245463                                                           15    9605
XP_005245462                                                           15    9605
>NP_919047
          Length = 520

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTLLQ+LQ
Sbjct: 347 NRTLLQQLQ 355
>NP_443086
          Length = 519

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTLLQ+LQ
Sbjct: 343 NRTLLQQLQ 351
>XP_005250598
          Length = 457

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTLLQ+LQ
Sbjct: 284 NRTLLQQLQ 292
>NP_060513
          Length = 986

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  NRTLLQRLQ 9
          NRTL++R+Q
Sbjct: 76 NRTLVRRVQ 84
>XP_006718666
          Length = 928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  NRTLLQRLQ 9
          NRTL++R+Q
Sbjct: 48 NRTLVRRVQ 56
>XP_006718665
          Length = 980

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  NRTLLQRLQ 9
          NRTL++R+Q
Sbjct: 48 NRTLVRRVQ 56
>XP_006718664
          Length = 997

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718663
          Length = 1001

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718662
          Length = 1019

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718661
          Length = 1023

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718660
          Length = 1027

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718659
          Length = 1045

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718658
          Length = 1048

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718657
          Length = 1048

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>XP_006718656
          Length = 1049

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           NRTL++R+Q
Sbjct: 117 NRTLVRRVQ 125
>NP_001271332
          Length = 279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  NRTLLQRLQ 9
          NR LLQ LQ
Sbjct: 14 NRVLLQALQ 22
>NP_079030
          Length = 388

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  NRTLLQRLQ 9
          NR LLQ LQ
Sbjct: 14 NRVLLQALQ 22
>XP_005248658
          Length = 350

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  NRTLLQRLQ 9
          NR LLQ LQ
Sbjct: 14 NRVLLQALQ 22
>NP_004989
          Length = 1108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           ++TLLQ+LQ
Sbjct: 478 DQTLLQKLQ 486
>NP_036467
          Length = 1098

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           ++TLLQ+LQ
Sbjct: 476 DQTLLQKLQ 484
>NP_115766
          Length = 293

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NRTLLQRLQ 9
           NRTL Q+L+
Sbjct: 152 NRTLTQKLR 160
>NP_705833
          Length = 2970

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NRTLLQR 7
           NRTL+QR
Sbjct: 417 NRTLVQR 423
>XP_005272534
          Length = 1071

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           ++TLLQ+LQ
Sbjct: 449 DQTLLQKLQ 457
>XP_005272533
          Length = 1096

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           ++TLLQ+LQ
Sbjct: 474 DQTLLQKLQ 482
>XP_005272532
          Length = 1100

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           ++TLLQ+LQ
Sbjct: 478 DQTLLQKLQ 486
>XP_006718546
          Length = 513

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NRTLLQRL 8
           NRT LQRL
Sbjct: 187 NRTNLQRL 194
>XP_005247174
          Length = 2679

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NRTLLQR 7
           NRTL+QR
Sbjct: 126 NRTLVQR 132
>NP_055992
          Length = 619

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   NRTLLQRL 8
           NRT LQRL
Sbjct: 293 NRTNLQRL 300
>NP_079019
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NRTLLQRLQ 9
           N+TL+++LQ
Sbjct: 131 NQTLMKKLQ 139
>NP_001363
          Length = 4486

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NRTLLQRL 8
            N+T LQRL
Sbjct: 3844 NKTALQRL 3851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           RTL++R+Q
Sbjct: 990 RTLMERVQ 997
>XP_006721528
          Length = 3869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    NRTLLQRL 8
            N+T LQRL
Sbjct: 3844 NKTALQRL 3851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           RTL++R+Q
Sbjct: 990 RTLMERVQ 997
>NP_004653
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NRTLLQRL 8
           N+T LQRL
Sbjct: 156 NKTALQRL 163
>NP_076915
          Length = 725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           ++LLQRLQ
Sbjct: 352 QSLLQRLQ 359
>NP_002445
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           ++LLQRLQ
Sbjct: 325 QSLLQRLQ 332
>NP_000024
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  NRTLLQRL 8
          NR  LQRL
Sbjct: 68 NRVFLQRL 75
>NP_001269721
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NRTLLQRLQ 9
           +RTLLQ+ Q
Sbjct: 245 HRTLLQQTQ 253
>NP_001165415
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQ+LQ
Sbjct: 285 TLLQKLQ 291
>NP_079430
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQ+LQ
Sbjct: 305 TLLQKLQ 311
>XP_006721530
          Length = 2746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           RTL++R+Q
Sbjct: 990 RTLMERVQ 997
>XP_006721529
          Length = 2817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           RTL++R+Q
Sbjct: 990 RTLMERVQ 997
>XP_006714537
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RTLLQRLQ 9
           ++LLQRLQ
Sbjct: 352 QSLLQRLQ 359
>XP_005246720
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NRTLLQRLQ 9
           +RTLLQ+ Q
Sbjct: 390 HRTLLQQTQ 398
>NP_001035869
          Length = 726

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NRTLLQRLQ 9
           +RTLLQ+ Q
Sbjct: 455 HRTLLQQTQ 463
>NP_060559
          Length = 726

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NRTLLQRLQ 9
           +RTLLQ+ Q
Sbjct: 455 HRTLLQQTQ 463
>NP_001124437
          Length = 785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQ+LQ
Sbjct: 388 TLLQKLQ 394
>NP_277052
          Length = 1731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NRTLLQRLQ 9
           ++ LLQRLQ
Sbjct: 398 HQLLLQRLQ 406
>NP_612486
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RTLLQR 7
           RTLLQR
Sbjct: 677 RTLLQR 682
>NP_001157281
          Length = 1941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTLLQR 7
          RTLLQR
Sbjct: 88 RTLLQR 93
>NP_001020016
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQRL+
Sbjct: 566 TLLQRLK 572
>NP_964012
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQRL+
Sbjct: 639 TLLQRLK 645
>NP_008865
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQRL+
Sbjct: 585 TLLQRLK 591
>NP_001248309
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TLLQRLQ 9
           TLLQRL+
Sbjct: 570 TLLQRLK 576
>NP_001185463
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RTLLQRLQ 9
          RTL +RLQ
Sbjct: 42 RTLCRRLQ 49
>NP_001185461
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 673 RTLCRRLQ 680
>NP_001020774
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TLLQRLQ 9
          TLLQRL+
Sbjct: 29 TLLQRLR 35
>NP_000440
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TLLQRLQ 9
          TLLQRL+
Sbjct: 29 TLLQRLR 35
>NP_115682
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  NRTLLQRLQ 9
          +R +LQR+Q
Sbjct: 85 SRAILQRVQ 93
>NP_001185462
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 672 RTLCRRLQ 679
>XP_006725317
          Length = 1745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTLLQR 7
          RTLLQR
Sbjct: 88 RTLLQR 93
>XP_005259715
          Length = 195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  NRTLLQRLQ 9
          +R +LQR+Q
Sbjct: 59 SRAILQRVQ 67
>XP_005256511
          Length = 1746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  RTLLQR 7
          RTLLQR
Sbjct: 88 RTLLQR 93
>XP_005254235
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RTLLQR 7
           RTLLQR
Sbjct: 678 RTLLQR 683
>XP_005254233
          Length = 1228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RTLLQR 7
           RTLLQR
Sbjct: 678 RTLLQR 683
>XP_005254234
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RTLLQR 7
           RTLLQR
Sbjct: 678 RTLLQR 683
>XP_005251053
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 625 RTLCRRLQ 632
>XP_005251052
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 627 RTLCRRLQ 634
>XP_005251051
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 687 RTLCRRLQ 694
>XP_005251050
          Length = 895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 694 RTLCRRLQ 701
>XP_006716657
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RTLLQRLQ 9
           RTL +RLQ
Sbjct: 695 RTLCRRLQ 702
>XP_005245463
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TLLQRLQ 9
          TLLQRL+
Sbjct: 29 TLLQRLR 35
>XP_005245462
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TLLQRLQ 9
          TLLQRL+
Sbjct: 29 TLLQRLR 35
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.137    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 446,443
Number of extensions: 835
Number of successful extensions: 73
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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