Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              20     509
XP_005273257                                                           20     509
NP_004177                                                              17    4312
XP_006713352                                                           17    4312
XP_005265439                                                           17    4312
XP_005265438                                                           17    4312
NP_001103984                                                           16    5631
NP_874367                                                              16    5631
NP_001277289                                                           16    5631
NP_001005463                                                           16    5631
NP_076870                                                              16    5631
XP_006723663                                                           16    5631
XP_005260827                                                           16    5631
XP_006717807                                                           16    5631
XP_006717806                                                           16    5631
XP_005252726                                                           16    5631
XP_006717805                                                           16    5631
XP_006717804                                                           16    5631
XP_005252725                                                           16    5631
XP_005252724                                                           16    5631
XP_006717803                                                           16    5631
XP_006717802                                                           16    5631
XP_006714890                                                           16    5631
XP_005265891                                                           16    5631
XP_005265890                                                           16    5631
NP_620130                                                              16    7355
NP_003965                                                              16    7355
NP_775901                                                              16    7355
XP_005276276                                                           16    7355
XP_005266736                                                           16    7355
XP_006722497                                                           16    7355
XP_006719005                                                           16    7355
XP_005271789                                                           16    7355
XP_005271786                                                           16    7355
XP_005271785                                                           16    7355
XP_005271784                                                           16    7355
XP_006716474                                                           16    7355
XP_005273738                                                           16    7355
XP_005273737                                                           16    7355
XP_005263905                                                           16    7355
XP_005275986                                                           16    7355
NP_659433                                                              15    9605
NP_149094                                                              15    9605
NP_001167622                                                           15    9605
NP_001167621                                                           15    9605
NP_001138890                                                           15    9605
NP_878899                                                              15    9605
NP_008949                                                              15    9605
XP_006724234                                                           15    9605
XP_005261462                                                           15    9605
XP_006717006                                                           15    9605
XP_006717005                                                           15    9605
XP_006717004                                                           15    9605
XP_006717003                                                           15    9605
XP_005251736                                                           15    9605
XP_006713597                                                           15    9605
XP_006713596                                                           15    9605
XP_006713595                                                           15    9605
XP_006713594                                                           15    9605
>NP_064450
          Length = 1722

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NQNAQKNAA 9
           NQNAQ NAA
Sbjct: 583 NQNAQTNAA 591
>XP_005273257
          Length = 1726

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NQNAQKNAA 9
           NQNAQ NAA
Sbjct: 583 NQNAQTNAA 591
>NP_004177
          Length = 785

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           N NA KNA
Sbjct: 602 NSNANKNA 609
>XP_006713352
          Length = 588

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           N NA KNA
Sbjct: 405 NSNANKNA 412
>XP_005265439
          Length = 754

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           N NA KNA
Sbjct: 571 NSNANKNA 578
>XP_005265438
          Length = 785

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           N NA KNA
Sbjct: 602 NSNANKNA 609
>NP_001103984
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 192 NQNCLKNA 199
>NP_874367
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 172 NQNCLKNA 179
>NP_001277289
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>NP_001005463
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>NP_076870
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006723663
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 165 NQNCLKNA 172
>XP_005260827
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 196 NQNCLKNA 203
>XP_006717807
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006717806
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_005252726
          Length = 587

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006717805
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006717804
          Length = 596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_005252725
          Length = 596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_005252724
          Length = 620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006717803
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006717802
          Length = 629

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_006714890
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 157 NQNCLKNA 164
>XP_005265891
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>XP_005265890
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NQNAQKNA 8
           NQN  KNA
Sbjct: 195 NQNCLKNA 202
>NP_620130
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NQNAQKN 7
           NQN+QK+
Sbjct: 164 NQNSQKS 170
>NP_003965
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   NAQKNAA 9
           +AQKNAA
Sbjct: 243 SAQKNAA 249
>NP_775901
          Length = 2226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    NQNAQKNAA 9
            NQNAQ+  A
Sbjct: 2155 NQNAQRIGA 2163
>XP_005276276
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  NQNAQKN 7
          NQN +KN
Sbjct: 17 NQNTKKN 23
>XP_005266736
          Length = 1314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    NQNAQKNAA 9
            NQNAQ+  A
Sbjct: 1243 NQNAQRIGA 1251
>XP_006722497
          Length = 2227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    NQNAQKNAA 9
            NQNAQ+  A
Sbjct: 2156 NQNAQRIGA 2164
>XP_006719005
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NQNAQKN 7
           NQN+QK+
Sbjct: 167 NQNSQKS 173
>XP_005271789
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NQNAQKN 7
           NQN+QK+
Sbjct: 167 NQNSQKS 173
>XP_005271786
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  NQNAQKN 7
          NQN+QK+
Sbjct: 27 NQNSQKS 33
>XP_005271785
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  NQNAQKN 7
          NQN+QK+
Sbjct: 27 NQNSQKS 33
>XP_005271784
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NQNAQKN 7
           NQN+QK+
Sbjct: 167 NQNSQKS 173
>XP_006716474
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  NAQKNAA 9
          +AQKNAA
Sbjct: 89 SAQKNAA 95
>XP_005273738
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  NAQKNAA 9
          +AQKNAA
Sbjct: 89 SAQKNAA 95
>XP_005273737
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   NAQKNAA 9
           +AQKNAA
Sbjct: 149 SAQKNAA 155
>XP_005263905
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  NQNAQKN 7
          NQN +KN
Sbjct: 17 NQNTKKN 23
>XP_005275986
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  NQNAQKN 7
          NQN +KN
Sbjct: 17 NQNTKKN 23
>NP_659433
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 198 NHNGQKN 204
>NP_149094
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NQNAQKNAA 9
           N+N QK+A+
Sbjct: 646 NKNRQKSAS 654
>NP_001167622
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 202 NHNGQKN 208
>NP_001167621
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 305 NHNGQKN 311
>NP_001138890
          Length = 2481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    QNAQKNA 8
            QN Q+NA
Sbjct: 1757 QNGQRNA 1763
>NP_878899
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 305 NHNGQKN 311
>NP_008949
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QNAQKNAA 9
            QN +KNA+
Sbjct: 2316 QNQEKNAS 2323
>XP_006724234
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    QNAQKNA 8
            QN Q+NA
Sbjct: 1639 QNGQRNA 1645
>XP_005261462
          Length = 2473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    QNAQKNA 8
            QN Q+NA
Sbjct: 1757 QNGQRNA 1763
>XP_006717006
          Length = 1760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QNAQKNAA 9
            QN +KNA+
Sbjct: 1751 QNQEKNAS 1758
>XP_006717005
          Length = 1788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QNAQKNAA 9
            QN +KNA+
Sbjct: 1779 QNQEKNAS 1786
>XP_006717004
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QNAQKNAA 9
            QN +KNA+
Sbjct: 2231 QNQEKNAS 2238
>XP_006717003
          Length = 2278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QNAQKNAA 9
            QN +KNA+
Sbjct: 2269 QNQEKNAS 2276
>XP_005251736
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QNAQKNAA 9
            QN +KNA+
Sbjct: 2316 QNQEKNAS 2323
>XP_006713597
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 280 NHNGQKN 286
>XP_006713596
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 280 NHNGQKN 286
>XP_006713595
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 290 NHNGQKN 296
>XP_006713594
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NQNAQKN 7
           N N QKN
Sbjct: 290 NHNGQKN 296
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285   0.0939    0.224 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 433,850
Number of extensions: 803
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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