Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     299
NP_006382                                                              17    4312
XP_005264070                                                           17    4312
NP_001193560                                                           17    4312
NP_001047                                                              17    4312
NP_001229468                                                           16    5631
NP_054790                                                              16    5631
NP_057363                                                              16    5631
XP_006723818                                                           16    5631
XP_006723817                                                           16    5631
XP_006723816                                                           16    5631
XP_006723815                                                           16    5631
XP_006723814                                                           16    5631
XP_006723813                                                           16    5631
XP_005260405                                                           16    5631
NP_542377                                                              16    7355
NP_542378                                                              16    7355
NP_005983                                                              16    7355
NP_002214                                                              16    7355
NP_001239542                                                           16    7355
NP_001157869                                                           16    7355
NP_001129958                                                           16    7355
NP_005986                                                              16    7355
NP_001239541                                                           16    7355
NP_001014972                                                           16    7355
NP_055312                                                              16    7355
XP_006724375                                                           16    7355
XP_005261326                                                           16    7355
XP_006719127                                                           16    7355
XP_005264321                                                           16    7355
XP_006712053                                                           16    7355
XP_005264320                                                           16    7355
XP_006712052                                                           16    7355
XP_005264319                                                           16    7355
XP_005264318                                                           16    7355
NP_005693                                                              16    7355
NP_006006                                                              15    9605
NP_624361                                                              15    9605
NP_112185                                                              15    9605
NP_997211                                                              15    9605
NP_005206                                                              15    9605
NP_060736                                                              15    9605
NP_004710                                                              15    9605
XP_005258261                                                           15    9605
XP_006719755                                                           15    9605
XP_005269287                                                           15    9605
XP_005247635                                                           15    9605
XP_005247634                                                           15    9605
XP_006713750                                                           15    9605
XP_006712378                                                           15    9605
XP_005263945                                                           15    9605
XP_006712377                                                           15    9605
XP_006712376                                                           15    9605
XP_006712375                                                           15    9605
XP_006712374                                                           15    9605
XP_006712373                                                           15    9605
XP_006712372                                                           15    9605
XP_006712371                                                           15    9605
XP_006712370                                                           15    9605
XP_005263941                                                           15    9605
XP_006712369                                                           15    9605
XP_005263939                                                           15    9605
XP_006712368                                                           15    9605
XP_006712367                                                           15    9605
XP_006712366                                                           15    9605
XP_006712365                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    NQLSTQMLP 9
            NQLSTQ+LP
Sbjct: 1052 NQLSTQILP 1060
>NP_006382
          Length = 1038

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NQLSTQMLP 9
           NQ+S Q+LP
Sbjct: 855 NQVSGQILP 863
>XP_005264070
          Length = 298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           LSTQ+LP
Sbjct: 112 LSTQLLP 118
>NP_001193560
          Length = 450

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NQLSTQMLP 9
           N LST+M P
Sbjct: 289 NALSTEMTP 297
>NP_001047
          Length = 296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           LSTQ+LP
Sbjct: 110 LSTQLLP 116
>NP_001229468
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 761 QMSGQMLP 768
>NP_054790
          Length = 2063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 761 QMSGQMLP 768
>NP_057363
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NQLSTQMLP 9
           N++ST +LP
Sbjct: 559 NKMSTYLLP 567
>XP_006723818
          Length = 1975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 761 QMSGQMLP 768
>XP_006723817
          Length = 2020

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 718 QMSGQMLP 725
>XP_006723816
          Length = 2034

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 761 QMSGQMLP 768
>XP_006723815
          Length = 2051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 749 QMSGQMLP 756
>XP_006723814
          Length = 2052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 750 QMSGQMLP 757
>XP_006723813
          Length = 2062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 761 QMSGQMLP 768
>XP_005260405
          Length = 2063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           Q+S QMLP
Sbjct: 761 QMSGQMLP 768
>NP_542377
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NQLSTQML 8
           NQL T+M+
Sbjct: 124 NQLGTEMI 131
>NP_542378
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NQLSTQML 8
           NQL T+M+
Sbjct: 124 NQLGTEMI 131
>NP_005983
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NQLSTQML 8
           NQL T+M+
Sbjct: 124 NQLGTEMI 131
>NP_002214
          Length = 2701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NQLSTQM 7
           NQ+STQ+
Sbjct: 750 NQISTQL 756
>NP_001239542
          Length = 1957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 970 NQLSISMAP 978
>NP_001157869
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           LST+M+P
Sbjct: 290 LSTEMIP 296
>NP_001129958
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           LST+M+P
Sbjct: 290 LSTEMIP 296
>NP_005986
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  NQLSTQML 8
          NQL T+M+
Sbjct: 79 NQLGTEMI 86
>NP_001239541
          Length = 1978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 970 NQLSISMAP 978
>NP_001014972
          Length = 1978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 970 NQLSISMAP 978
>NP_055312
          Length = 1978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 970 NQLSISMAP 978
>XP_006724375
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NQLSTQML 8
           NQL T+M+
Sbjct: 124 NQLGTEMI 131
>XP_005261326
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NQLSTQML 8
           NQL T+M+
Sbjct: 174 NQLGTEMI 181
>XP_006719127
          Length = 1865

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NQLSTQM 7
           NQ+STQ+
Sbjct: 750 NQISTQL 756
>XP_005264321
          Length = 1206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    NQLSTQMLP 9
            NQLS  M P
Sbjct: 1076 NQLSISMAP 1084
>XP_006712053
          Length = 1467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 459 NQLSISMAP 467
>XP_005264320
          Length = 1467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 459 NQLSISMAP 467
>XP_006712052
          Length = 1467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   NQLSTQMLP 9
           NQLS  M P
Sbjct: 459 NQLSISMAP 467
>XP_005264319
          Length = 2049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    NQLSTQMLP 9
            NQLS  M P
Sbjct: 1076 NQLSISMAP 1084
>XP_005264318
          Length = 2084

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    NQLSTQMLP 9
            NQLS  M P
Sbjct: 1076 NQLSISMAP 1084
>NP_005693
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NQLSTQML 8
           NQLS Q+L
Sbjct: 213 NQLSPQLL 220
>NP_006006
          Length = 2285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    NQLSTQMLP 9
            NQ STQ  P
Sbjct: 1341 NQFSTQGTP 1349
>NP_624361
          Length = 2068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    NQLSTQMLP 9
            NQ STQ  P
Sbjct: 1341 NQFSTQGTP 1349
>NP_112185
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NQLSTQMLP 9
           + LST++LP
Sbjct: 175 HDLSTRLLP 183
>NP_997211
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 541 QLSAELLP 548
>NP_005206
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSTQMLP 9
           LST MLP
Sbjct: 840 LSTPMLP 846
>NP_060736
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           L+TQ+LP
Sbjct: 333 LTTQLLP 339
>NP_004710
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NQLSTQMLP 9
            N +ST +LP
Sbjct: 1312 NNMSTPVLP 1320
>XP_005258261
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSTQMLP 9
           LST MLP
Sbjct: 840 LSTPMLP 846
>XP_006719755
          Length = 1418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NQLSTQMLP 9
            N +ST +LP
Sbjct: 1267 NNMSTPVLP 1275
>XP_005269287
          Length = 1527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NQLSTQMLP 9
            N +ST +LP
Sbjct: 1376 NNMSTPVLP 1384
>XP_005247635
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           L+TQ+LP
Sbjct: 333 LTTQLLP 339
>XP_005247634
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           L+TQ+LP
Sbjct: 333 LTTQLLP 339
>XP_006713750
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSTQMLP 9
           L+TQ+LP
Sbjct: 333 LTTQLLP 339
>XP_006712378
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 541 QLSAELLP 548
>XP_005263945
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 541 QLSAELLP 548
>XP_006712377
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 420 QLSAELLP 427
>XP_006712376
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712375
          Length = 685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712374
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712373
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 470 QLSAELLP 477
>XP_006712372
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 470 QLSAELLP 477
>XP_006712371
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712370
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 476 QLSAELLP 483
>XP_005263941
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712369
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_005263939
          Length = 821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 541 QLSAELLP 548
>XP_006712368
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712367
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712366
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
>XP_006712365
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLSTQMLP 9
           QLS ++LP
Sbjct: 547 QLSAELLP 554
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.119    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 340,434
Number of extensions: 666
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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