Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              21     175
XP_005250103                                                           21     175
XP_005250102                                                           21     175
NP_065875                                                              19     665
XP_005252604                                                           19     665
XP_005252603                                                           19     665
XP_005252601                                                           19     665
XP_006717551                                                           19     665
XP_005252600                                                           19     665
XP_005252599                                                           19     665
XP_006717550                                                           19     665
NP_001121167                                                           18    1482
NP_001161066                                                           18    1482
NP_000299                                                              18    1482
NP_067047                                                              18    1935
XP_006717281                                                           18    1935
XP_006717280                                                           18    1935
XP_006717279                                                           18    1935
XP_006717278                                                           18    1935
XP_006717277                                                           18    1935
XP_006717276                                                           18    1935
XP_006717275                                                           18    1935
XP_006717274                                                           18    1935
XP_006717273                                                           18    1935
XP_006717272                                                           18    1935
NP_037383                                                              17    3301
NP_002636                                                              17    3301
NP_001171525                                                           17    3301
XP_006719643                                                           17    3301
XP_006719642                                                           17    3301
XP_006719641                                                           17    3301
XP_005253037                                                           17    3301
XP_005253036                                                           17    3301
XP_005253035                                                           17    3301
XP_005253034                                                           17    3301
NP_005499                                                              17    3301
NP_009215                                                              17    4312
NP_078838                                                              17    4312
NP_004939                                                              16    5631
NP_077739                                                              16    5631
NP_001025178                                                           16    7355
NP_001119                                                              16    7355
NP_060941                                                              16    7355
NP_004940                                                              15    9605
NP_005261                                                              15    9605
NP_077740                                                              15    9605
NP_005017                                                              15    9605
NP_808220                                                              15    9605
NP_001017390                                                           15    9605
NP_001186127                                                           15    9605
NP_060779                                                              15    9605
NP_055469                                                              15    9605
NP_077741                                                              15    9605
NP_001932                                                              15    9605
XP_006726684                                                           15    9605
XP_005276564                                                           15    9605
XP_005276563                                                           15    9605
XP_005258263                                                           15    9605
XP_006712486                                                           15    9605
XP_006712485                                                           15    9605
XP_006710753                                                           15    9605
XP_005263530                                                           15    9605
XP_006710752                                                           15    9605
XP_006710751                                                           15    9605
XP_006710750                                                           15    9605
XP_006710749                                                           15    9605
NP_004578                                                              15    9605
NP_001036041                                                           15    9605
>NP_004324
          Length = 766

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           NPTDVA+SN
Sbjct: 140 NPTDVARSN 148
>XP_005250103
          Length = 758

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           NPTDVA+SN
Sbjct: 140 NPTDVARSN 148
>XP_005250102
          Length = 767

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           NPTDVA+SN
Sbjct: 140 NPTDVARSN 148
>NP_065875
          Length = 1958

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>XP_005252604
          Length = 1386

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>XP_005252603
          Length = 1457

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>XP_005252601
          Length = 1948

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 243 SPTDVAKSN 251
>XP_006717551
          Length = 1958

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>XP_005252600
          Length = 1958

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>XP_005252599
          Length = 1958

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>XP_006717550
          Length = 1958

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   NPTDVAQSN 9
           +PTDVA+SN
Sbjct: 253 SPTDVAKSN 261
>NP_001121167
          Length = 480

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           N T+VAQSN
Sbjct: 145 NDTEVAQSN 153
>NP_001161066
          Length = 481

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           N T+VAQSN
Sbjct: 146 NDTEVAQSN 154
>NP_000299
          Length = 498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           N T+VAQSN
Sbjct: 163 NDTEVAQSN 171
>NP_067047
          Length = 2506

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717281
          Length = 1702

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717280
          Length = 2221

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717279
          Length = 2506

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717278
          Length = 2566

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717277
          Length = 2567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717276
          Length = 2567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717275
          Length = 2567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717274
          Length = 2567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717273
          Length = 2567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>XP_006717272
          Length = 2567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PTDVAQSN 9
          PTDVA+ N
Sbjct: 33 PTDVAEDN 40
>NP_037383
          Length = 121

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NPTDVAQSN 9
           +PTDV Q N
Sbjct: 99  SPTDVNQEN 107
>NP_002636
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           +PTD AQS+
Sbjct: 665 SPTDCAQSS 673
>NP_001171525
          Length = 103

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NPTDVAQSN 9
          +PTDV Q N
Sbjct: 81 SPTDVNQEN 89
>XP_006719643
          Length = 103

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NPTDVAQSN 9
          +PTDV Q N
Sbjct: 81 SPTDVNQEN 89
>XP_006719642
          Length = 121

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NPTDVAQSN 9
           +PTDV Q N
Sbjct: 99  SPTDVNQEN 107
>XP_006719641
          Length = 121

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NPTDVAQSN 9
           +PTDV Q N
Sbjct: 99  SPTDVNQEN 107
>XP_005253037
          Length = 1306

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           +PTD AQS+
Sbjct: 285 SPTDCAQSS 293
>XP_005253036
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           +PTD AQS+
Sbjct: 665 SPTDCAQSS 673
>XP_005253035
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           +PTD AQS+
Sbjct: 665 SPTDCAQSS 673
>XP_005253034
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NPTDVAQSN 9
           +PTD AQS+
Sbjct: 665 SPTDCAQSS 673
>NP_005499
          Length = 360

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1 NPTDVAQS 8
         NPTD+A +
Sbjct: 2 NPTDIADT 9
>NP_009215
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   PTDVAQ 7
           PTDVAQ
Sbjct: 219 PTDVAQ 224
>NP_078838
          Length = 1094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PTDVAQSN 9
           PTDVA S+
Sbjct: 787 PTDVAHSH 794
>NP_004939
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 725 PEDIAQQN 732
>NP_077739
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 725 PEDIAQQN 732
>NP_001025178
          Length = 825

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   PTDVAQSN 9
           PT++ Q+N
Sbjct: 598 PTEIVQTN 605
>NP_001119
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   PTDVAQSN 9
           PT++ Q+N
Sbjct: 595 PTEIVQTN 602
>NP_060941
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  NPTDVAQS 8
          NP  VAQS
Sbjct: 56 NPRQVAQS 63
>NP_004940
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 729 PDDLAQQN 736
>NP_005261
          Length = 1586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NPTDVAQSN 9
           +P DVAQ +
Sbjct: 149 SPADVAQEH 157
>NP_077740
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 729 PDDLAQQN 736
>NP_005017
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 454 NPTGTVRSN 462
>NP_808220
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NPTDVAQS 8
           NP DVA S
Sbjct: 131 NPKDVAVS 138
>NP_001017390
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NPTDVAQS 8
           NP DVA S
Sbjct: 131 NPKDVAVS 138
>NP_001186127
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NPTDVAQS 8
           NP++ AQS
Sbjct: 368 NPSEFAQS 375
>NP_060779
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NPTDVAQS 8
           NP++ AQS
Sbjct: 368 NPSEFAQS 375
>NP_055469
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PTDVAQS 8
           PT+VAQ+
Sbjct: 285 PTEVAQT 291
>NP_077741
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 724 PEDLAQQN 731
>NP_001932
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 724 PEDLAQQN 731
>XP_006726684
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NPTDVAQS 8
           NP DVA S
Sbjct: 131 NPKDVAVS 138
>XP_005276564
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NPTDVAQS 8
           NP DVA S
Sbjct: 131 NPKDVAVS 138
>XP_005276563
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NPTDVAQS 8
           NP DVA S
Sbjct: 131 NPKDVAVS 138
>XP_005258263
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PTDVAQSN 9
           P D+AQ N
Sbjct: 586 PDDLAQQN 593
>XP_006712486
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  NPTDVAQSN 9
          +P DVAQ +
Sbjct: 84 SPADVAQEH 92
>XP_006712485
          Length = 1569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NPTDVAQSN 9
           +P DVAQ +
Sbjct: 149 SPADVAQEH 157
>XP_006710753
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 425 NPTGTVRSN 433
>XP_005263530
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 454 NPTGTVRSN 462
>XP_006710752
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 454 NPTGTVRSN 462
>XP_006710751
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 454 NPTGTVRSN 462
>XP_006710750
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 454 NPTGTVRSN 462
>XP_006710749
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NPTDVAQSN 9
           NPT   +SN
Sbjct: 454 NPTGTVRSN 462
>NP_004578
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TDVAQS 8
           TDVAQS
Sbjct: 180 TDVAQS 185
>NP_001036041
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TDVAQS 8
           TDVAQS
Sbjct: 180 TDVAQS 185
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.108    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 571,838
Number of extensions: 1030
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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