Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1482
NP_000242                                                              18    1482
XP_005264389                                                           18    1482
NP_000443                                                              17    3301
NP_065954                                                              17    4312
NP_001361                                                              16    5631
XP_006712019                                                           16    5631
NP_443075                                                              16    7355
NP_001258152                                                           16    7355
NP_001092093                                                           16    7355
NP_065928                                                              16    7355
XP_005256527                                                           16    7355
XP_006711892                                                           16    7355
XP_006711891                                                           16    7355
XP_006711890                                                           16    7355
XP_006711889                                                           16    7355
XP_005273367                                                           16    7355
XP_005273366                                                           16    7355
XP_006711888                                                           16    7355
XP_006711887                                                           16    7355
XP_005273364                                                           16    7355
XP_005273362                                                           16    7355
XP_005273361                                                           16    7355
XP_006711886                                                           16    7355
XP_006711885                                                           16    7355
XP_005273359                                                           16    7355
XP_006711884                                                           16    7355
XP_005273357                                                           16    7355
XP_005273356                                                           16    7355
XP_005273358                                                           16    7355
XP_005273355                                                           16    7355
XP_005273353                                                           16    7355
XP_005273352                                                           16    7355
XP_005273354                                                           16    7355
XP_005273349                                                           16    7355
XP_006711883                                                           16    7355
XP_005273350                                                           16    7355
XP_005273351                                                           16    7355
XP_006711882                                                           16    7355
XP_005273348                                                           16    7355
XP_005273346                                                           16    7355
XP_005273347                                                           16    7355
XP_005273345                                                           16    7355
XP_005273344                                                           16    7355
NP_001091846                                                           15    9605
NP_001010890                                                           15    9605
NP_001139816                                                           15    9605
NP_001013425                                                           15    9605
NP_852607                                                              15    9605
NP_714544                                                              15    9605
NP_001258758                                                           15    9605
XP_006726395                                                           15    9605
XP_005276181                                                           15    9605
XP_005276180                                                           15    9605
XP_005276179                                                           15    9605
XP_006725019                                                           15    9605
XP_006720470                                                           15    9605
XP_006716776                                                           15    9605
XP_006711146                                                           15    9605
XP_006711145                                                           15    9605
XP_006711143                                                           15    9605
XP_006710315                                                           15    9605
NP_001010889                                                           15    9605
>NP_001245210
          Length = 868

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  NLQSVVLS 9
          NLQSVVLS
Sbjct: 8  NLQSVVLS 15
>NP_000242
          Length = 934

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  NLQSVVLS 9
          NLQSVVLS
Sbjct: 74 NLQSVVLS 81
>XP_005264389
          Length = 921

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  NLQSVVLS 9
          NLQSVVLS
Sbjct: 74 NLQSVVLS 81
>NP_000443
          Length = 348

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  NNLQSVVLS 9
          NN+ SVVLS
Sbjct: 27 NNILSVVLS 35
>NP_065954
          Length = 922

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  NNLQSVVL 8
          NN++SVVL
Sbjct: 55 NNIRSVVL 62
>NP_001361
          Length = 4158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NNLQSVV 7
           NNLQSV+
Sbjct: 846 NNLQSVL 852
>XP_006712019
          Length = 4158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NNLQSVV 7
           NNLQSV+
Sbjct: 846 NNLQSVL 852
>NP_443075
          Length = 6620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2483 LQSVVLS 2489
>NP_001258152
          Length = 8923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2912 LQSVVLS 2918
>NP_001092093
          Length = 7968

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2483 LQSVVLS 2489
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NNLQSVVLS 9
            NN+QS++ S
Sbjct: 2452 NNVQSIIES 2460
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    NNLQSVVLS 9
            NN+QS++ S
Sbjct: 2452 NNVQSIIES 2460
>XP_006711892
          Length = 6865

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2728 LQSVVLS 2734
>XP_006711891
          Length = 8925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2912 LQSVVLS 2918
>XP_006711890
          Length = 6957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711889
          Length = 7297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273367
          Length = 7677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273366
          Length = 7678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711888
          Length = 8059

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711887
          Length = 8499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273364
          Length = 8653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273362
          Length = 8675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273361
          Length = 8763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711886
          Length = 8833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711885
          Length = 8835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273359
          Length = 8843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2636 LQSVVLS 2642
>XP_006711884
          Length = 8847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273357
          Length = 8851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273356
          Length = 8851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273358
          Length = 8851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273355
          Length = 8924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273353
          Length = 8935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2728 LQSVVLS 2734
>XP_005273352
          Length = 8935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2728 LQSVVLS 2734
>XP_005273354
          Length = 8935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2728 LQSVVLS 2734
>XP_005273349
          Length = 8939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711883
          Length = 8939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273350
          Length = 8939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273351
          Length = 8939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_006711882
          Length = 8977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2770 LQSVVLS 2776
>XP_005273348
          Length = 9015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273346
          Length = 9026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273347
          Length = 9026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273345
          Length = 9026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>XP_005273344
          Length = 9027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LQSVVLS 9
            LQSVVLS
Sbjct: 2820 LQSVVLS 2826
>NP_001091846
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>NP_001010890
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>NP_001139816
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>NP_001013425
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 233 NLQKLVLS 240
>NP_852607
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NNLQSVVLS 9
           NNL+ ++LS
Sbjct: 276 NNLKHLILS 284
>NP_714544
          Length = 1775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 741 NLQQLVLS 748
>NP_001258758
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQS +LS
Sbjct: 96  NLQSPILS 103
>XP_006726395
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 234 NLQKLVLS 241
>XP_005276181
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_005276180
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_005276179
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_006725019
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_006720470
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NLQSVVLS 9
          NLQ +VLS
Sbjct: 53 NLQQLVLS 60
>XP_006716776
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQS +LS
Sbjct: 96  NLQSPILS 103
>XP_006711146
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_006711145
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_006711143
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>XP_006710315
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 235 NLQKLVLS 242
>NP_001010889
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLQSVVLS 9
           NLQ +VLS
Sbjct: 233 NLQKLVLS 240
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.118    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 291,827
Number of extensions: 460
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package