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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              20     299
NP_001120972                                                           20     299
XP_006716054                                                           20     299
XP_006716053                                                           20     299
XP_006716052                                                           20     299
XP_006716051                                                           20     299
NP_001129490                                                           17    4312
NP_001278092                                                           17    4312
NP_000111                                                              17    4312
NP_443124                                                              16    7355
NP_001070248                                                           16    7355
NP_001171697                                                           15    9605
NP_061880                                                              15    9605
NP_001009584                                                           15    9605
NP_001123616                                                           15    9605
NP_006411                                                              15    9605
NP_001277137                                                           15    9605
NP_001277138                                                           15    9605
NP_001121695                                                           15    9605
NP_569713                                                              15    9605
NP_066548                                                              15    9605
NP_003726                                                              15    9605
NP_115265                                                              15    9605
XP_006724728                                                           15    9605
XP_006723746                                                           15    9605
XP_005260309                                                           15    9605
XP_006712976                                                           15    9605
XP_006712975                                                           15    9605
XP_006712974                                                           15    9605
XP_005264770                                                           15    9605
XP_005264768                                                           15    9605
XP_005264767                                                           15    9605
XP_006712973                                                           15    9605

>NP_000236
          Length = 1390

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NMSLIISNG 9
           NMS+IISNG
Sbjct: 635 NMSIIISNG 643



>NP_001120972
          Length = 1408

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NMSLIISNG 9
           NMS+IISNG
Sbjct: 635 NMSIIISNG 643



>XP_006716054
          Length = 960

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NMSLIISNG 9
           NMS+IISNG
Sbjct: 205 NMSIIISNG 213



>XP_006716053
          Length = 960

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NMSLIISNG 9
           NMS+IISNG
Sbjct: 205 NMSIIISNG 213



>XP_006716052
          Length = 1409

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NMSLIISNG 9
           NMS+IISNG
Sbjct: 654 NMSIIISNG 662



>XP_006716051
          Length = 1427

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NMSLIISNG 9
           NMS+IISNG
Sbjct: 654 NMSIIISNG 662



>NP_001129490
          Length = 455

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMSLIISN 8
           NM+L++SN
Sbjct: 249 NMALVLSN 256



>NP_001278092
          Length = 455

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMSLIISN 8
           NM+L++SN
Sbjct: 249 NMALVLSN 256



>NP_000111
          Length = 455

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMSLIISN 8
           NM+L++SN
Sbjct: 249 NMALVLSN 256



>NP_443124
          Length = 2459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NMSLIISNG 9
           N+S IIS G
Sbjct: 283 NLSCIISTG 291



>NP_001070248
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NMSLIISNG 9
           N+S IIS G
Sbjct: 283 NLSCIISTG 291



>NP_001171697
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   MSLIISNG 9
           MSL I NG
Sbjct: 282 MSLFIRNG 289



>NP_061880
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   MSLIISNG 9
           MSL I NG
Sbjct: 282 MSLFIRNG 289



>NP_001009584
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   MSLIISNG 9
           MSL I NG
Sbjct: 282 MSLFIRNG 289



>NP_001123616
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NMSLIISNG 9
          NM+LI  NG
Sbjct: 89 NMTLIGENG 97



>NP_006411
          Length = 1785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SLIISNG 9
            +L+ISNG
Sbjct: 1453 NLVISNG 1459



>NP_001277137
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>NP_001277138
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  MSLIISNG 9
          ++LII+NG
Sbjct: 92 LNLIINNG 99



>NP_001121695
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>NP_569713
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  MSLIISNG 9
          +SLI+ NG
Sbjct: 54 LSLILQNG 61



>NP_066548
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  NMSLIISNG 9
          NM+LI  NG
Sbjct: 89 NMTLIGENG 97



>NP_003726
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NMSLIISNG 9
           + SLI+ NG
Sbjct: 177 HFSLIVQNG 185



>NP_115265
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NMSLIISNG 9
           + SLI+ NG
Sbjct: 177 HFSLIVQNG 185



>XP_006724728
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   MSLIISNG 9
           MSL I NG
Sbjct: 345 MSLFIRNG 352



>XP_006723746
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLIISNG 9
           +L+ISNG
Sbjct: 845 NLVISNG 851



>XP_005260309
          Length = 1784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SLIISNG 9
            +L+ISNG
Sbjct: 1452 NLVISNG 1458



>XP_006712976
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>XP_006712975
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 135 LNLIINNG 142



>XP_006712974
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>XP_005264770
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>XP_005264768
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>XP_005264767
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



>XP_006712973
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIISNG 9
           ++LII+NG
Sbjct: 142 LNLIINNG 149



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.131    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 320,030
Number of extensions: 524
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)