Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     299
NP_036462                                                              20     299
NP_001243397                                                           20     299
XP_005269721                                                           20     299
NP_003292                                                              18    1135
NP_001092882                                                           18    1135
NP_006757                                                              18    1135
NP_001092883                                                           18    1135
XP_005273706                                                           18    1135
XP_006717495                                                           18    1935
XP_006717494                                                           18    1935
XP_006717493                                                           18    1935
XP_006717492                                                           18    1935
XP_006717490                                                           18    1935
XP_006717489                                                           18    1935
XP_006717488                                                           18    1935
XP_006717487                                                           18    1935
XP_006717486                                                           18    1935
NP_055840                                                              17    3301
XP_006711931                                                           17    3301
XP_006711930                                                           17    3301
XP_006711929                                                           17    3301
XP_006711928                                                           17    3301
XP_006711927                                                           17    3301
XP_006711926                                                           17    3301
XP_006711925                                                           17    3301
NP_904358                                                              16    5631
NP_001230728                                                           16    5631
NP_665879                                                              16    5631
XP_005266640                                                           16    5631
XP_005266639                                                           16    5631
XP_006719950                                                           16    5631
NP_057200                                                              16    5631
NP_001191230                                                           16    7355
NP_001191232                                                           16    7355
NP_001129488                                                           16    7355
NP_001191231                                                           16    7355
NP_001129603                                                           16    7355
NP_958817                                                              16    7355
NP_958816                                                              16    7355
NP_000475                                                              16    7355
NP_115954                                                              16    7355
NP_001245308                                                           16    7355
NP_659001                                                              16    7355
NP_001154178                                                           16    7355
NP_003834                                                              16    7355
NP_775821                                                              16    7355
NP_872363                                                              16    7355
XP_006719949                                                           16    7355
XP_006719948                                                           16    7355
XP_005266635                                                           16    7355
XP_006719947                                                           16    7355
XP_006719946                                                           16    7355
XP_006719945                                                           16    7355
XP_005271570                                                           16    7355
XP_005271569                                                           16    7355
XP_006718878                                                           16    7355
XP_005271568                                                           16    7355
XP_005251455                                                           16    7355
XP_005251456                                                           16    7355
XP_005251454                                                           16    7355
XP_005265657                                                           16    7355
XP_005265656                                                           16    7355
XP_005265655                                                           16    7355
XP_006713484                                                           16    7355
NP_055178                                                              15    9605
NP_001264984                                                           15    9605
NP_001106853                                                           15    9605
XP_005266395                                                           15    9605
XP_006712889                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            NMNMNT NA
Sbjct: 1691 NMNMNTLNA 1699
>NP_036462
          Length = 2073

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            NMNMNT NA
Sbjct: 1983 NMNMNTLNA 1991
>NP_001243397
          Length = 1890

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            NMNMNT NA
Sbjct: 1800 NMNMNTLNA 1808
>XP_005269721
          Length = 2073

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            NMNMNT NA
Sbjct: 1983 NMNMNTLNA 1991
>NP_003292
          Length = 398

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NMNMNTSN 8
           N+N+NTSN
Sbjct: 244 NLNVNTSN 251
>NP_001092882
          Length = 2004

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            +MNMNT NA
Sbjct: 1913 SMNMNTLNA 1921
>NP_006757
          Length = 2004

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            +MNMNT NA
Sbjct: 1913 SMNMNTLNA 1921
>NP_001092883
          Length = 2004

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            +MNMNT NA
Sbjct: 1913 SMNMNTLNA 1921
>XP_005273706
          Length = 1997

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    NMNMNTSNA 9
            +MNMNT NA
Sbjct: 1906 SMNMNTLNA 1914
>XP_006717495
          Length = 1037

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 773 NMNRNTTN 780
>XP_006717494
          Length = 1571

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 272 NMNRNTTN 279
>XP_006717493
          Length = 1610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 311 NMNRNTTN 318
>XP_006717492
          Length = 1635

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 773 NMNRNTTN 780
>XP_006717490
          Length = 1791

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 492 NMNRNTTN 499
>XP_006717489
          Length = 1945

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 773 NMNRNTTN 780
>XP_006717488
          Length = 2031

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 773 NMNRNTTN 780
>XP_006717487
          Length = 2071

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 773 NMNRNTTN 780
>XP_006717486
          Length = 2072

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           NMN NT+N
Sbjct: 773 NMNRNTTN 780
>NP_055840
          Length = 1184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711931
          Length = 1162

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711930
          Length = 1186

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711929
          Length = 1186

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711928
          Length = 1188

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711927
          Length = 1207

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711926
          Length = 1207

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>XP_006711925
          Length = 1209

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MNMNTSNA 9
           MN NTSN+
Sbjct: 225 MNSNTSNS 232
>NP_904358
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMNMNTSN 8
           N+N++TSN
Sbjct: 335 NVNISTSN 342
>NP_001230728
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMNMNTSN 8
           N+N++TSN
Sbjct: 335 NVNISTSN 342
>NP_665879
          Length = 349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           N+NM T+N
Sbjct: 165 NVNMKTNN 172
>XP_005266640
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMNMNTSN 8
           N+N++TSN
Sbjct: 335 NVNISTSN 342
>XP_005266639
          Length = 1048

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMNMNTSN 8
           N+N++TSN
Sbjct: 335 NVNISTSN 342
>XP_006719950
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NMNMNTSN 8
           N+N++TSN
Sbjct: 335 NVNISTSN 342
>NP_057200
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           N+NM T+N
Sbjct: 165 NVNMKTNN 172
>NP_001191230
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 42 NMHMNVQN 49
>NP_001191232
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 42 NMHMNVQN 49
>NP_001129488
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 37 NMHMNVQN 44
>NP_001191231
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 42 NMHMNVQN 49
>NP_001129603
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 7  NMHMNVQN 14
>NP_958817
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 42 NMHMNVQN 49
>NP_958816
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 42 NMHMNVQN 49
>NP_000475
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  NMNMNTSN 8
          NM+MN  N
Sbjct: 42 NMHMNVQN 49
>NP_115954
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NMNTSN 8
           N+NTSN
Sbjct: 156 NLNTSN 161
>NP_001245308
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MNMNTSNA 9
            ++MNT NA
Sbjct: 1090 LSMNTENA 1097
>NP_659001
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>NP_001154178
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>NP_003834
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>NP_775821
          Length = 1326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2 MNMNTSN 8
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>NP_872363
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NMNMNTS 7
           NMNMN +
Sbjct: 771 NMNMNVN 777
>XP_006719949
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>XP_006719948
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>XP_005266635
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 115 SLNANTSN 122
>XP_006719947
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>XP_006719946
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>XP_006719945
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NMNMNTSN 8
           ++N NTSN
Sbjct: 138 SLNANTSN 145
>XP_005271570
          Length = 1462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NMNMNTS 7
           NMNMN +
Sbjct: 734 NMNMNVN 740
>XP_005271569
          Length = 1462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NMNMNTS 7
           NMNMN +
Sbjct: 734 NMNMNVN 740
>XP_006718878
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NMNMNTS 7
           NMNMN +
Sbjct: 771 NMNMNVN 777
>XP_005271568
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NMNMNTS 7
           NMNMN +
Sbjct: 771 NMNMNVN 777
>XP_005251455
          Length = 1334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2 MNMNTSN 8
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_005251456
          Length = 1334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2 MNMNTSN 8
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_005251454
          Length = 1334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2 MNMNTSN 8
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_005265657
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MNMNTSNA 9
            ++MNT NA
Sbjct: 1072 LSMNTENA 1079
>XP_005265656
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MNMNTSNA 9
            ++MNT NA
Sbjct: 1077 LSMNTENA 1084
>XP_005265655
          Length = 1126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MNMNTSNA 9
            ++MNT NA
Sbjct: 1085 LSMNTENA 1092
>XP_006713484
          Length = 1255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    MNMNTSNA 9
            ++MNT NA
Sbjct: 1214 LSMNTENA 1221
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    MNMNTSN 8
            +NM+TSN
Sbjct: 3015 INMSTSN 3021
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    MNMNTSN 8
            +NM+TSN
Sbjct: 2868 INMSTSN 2874
>NP_001106853
          Length = 2093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NMNTSNA 9
            ++NTSNA
Sbjct: 2045 SLNTSNA 2051
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    MNMNTSN 8
            +NM+TSN
Sbjct: 3024 INMSTSN 3030
>XP_006712889
          Length = 2069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    NMNTSNA 9
            ++NTSNA
Sbjct: 2021 SLNTSNA 2027
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293   0.0966    0.244 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,849
Number of extensions: 821
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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