Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001254726                                                           17    3301
NP_055630                                                              17    3301
XP_005257931                                                           17    3301
XP_005257930                                                           17    3301
XP_005257929                                                           17    3301
XP_006722270                                                           17    3301
XP_006722269                                                           17    3301
XP_005257928                                                           17    3301
XP_006722268                                                           17    3301
XP_005257927                                                           17    3301
XP_006722267                                                           17    3301
XP_006722266                                                           17    3301
NP_001072986                                                           17    3301
NP_001007215                                                           17    4312
NP_055227                                                              17    4312
NP_001180263                                                           17    4312
NP_001002292                                                           17    4312
NP_659483                                                              17    4312
NP_079187                                                              17    4312
XP_005245149                                                           17    4312
NP_001253981                                                           16    5631
XP_005257983                                                           16    5631
XP_005256679                                                           16    5631
NP_001108446                                                           16    5631
NP_775259                                                              16    5631
NP_001028748                                                           16    5631
NP_001177203                                                           16    7355
NP_079409                                                              16    7355
NP_066958                                                              16    7355
NP_001006933                                                           16    7355
NP_001035282                                                           16    7355
NP_060303                                                              16    7355
XP_006725461                                                           16    7355
XP_006724090                                                           16    7355
XP_005267149                                                           16    7355
XP_006715612                                                           16    7355
XP_005264631                                                           16    7355
XP_005264630                                                           16    7355
XP_005264629                                                           16    7355
NP_006845                                                              15    9605
NP_001094073                                                           15    9605
NP_653299                                                              15    9605
NP_057839                                                              15    9605
NP_001267728                                                           15    9605
NP_006846                                                              15    9605
NP_002431                                                              15    9605
NP_006792                                                              15    9605
NP_690607                                                              15    9605
NP_004972                                                              15    9605
NP_001004740                                                           15    9605
>NP_001254726
          Length = 976

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 242 NLTGETQSL 250
>NP_055630
          Length = 989

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 255 NLTGETQSL 263
>XP_005257931
          Length = 1014

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 280 NLTGETQSL 288
>XP_005257930
          Length = 1032

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 299 NLTGETQSL 307
>XP_005257929
          Length = 1033

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 299 NLTGETQSL 307
>XP_006722270
          Length = 1044

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 255 NLTGETQSL 263
>XP_006722269
          Length = 1044

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 255 NLTGETQSL 263
>XP_005257928
          Length = 1051

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 274 NLTGETQSL 282
>XP_006722268
          Length = 1051

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 274 NLTGETQSL 282
>XP_005257927
          Length = 1057

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 280 NLTGETQSL 288
>XP_006722267
          Length = 1069

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 280 NLTGETQSL 288
>XP_006722266
          Length = 1076

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 299 NLTGETQSL 307
>NP_001072986
          Length = 976

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NLSGKSQSL 9
           NL+G++QSL
Sbjct: 242 NLTGETQSL 250
>NP_001007215
          Length = 185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLSGKSQSL 9
          NL+GKS S+
Sbjct: 76 NLNGKSYSM 84
>NP_055227
          Length = 228

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLSGKSQSL 9
           NL+GKS S+
Sbjct: 119 NLNGKSYSM 127
>NP_001180263
          Length = 450

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           N+SGK  SL
Sbjct: 315 NISGKQSSL 323
>NP_001002292
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           N+SGK  SL
Sbjct: 404 NISGKQSSL 412
>NP_659483
          Length = 384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NLSGKSQ 7
           NL+GKSQ
Sbjct: 121 NLNGKSQ 127
>NP_079187
          Length = 541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           N+SGK  SL
Sbjct: 406 NISGKQSSL 414
>XP_005245149
          Length = 185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLSGKSQSL 9
          NL+GKS S+
Sbjct: 76 NLNGKSYSM 84
>NP_001253981
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSG+S  L
Sbjct: 743 NLSGRSDKL 751
>XP_005257983
          Length = 850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSG+S  L
Sbjct: 664 NLSGRSDKL 672
>XP_005256679
          Length = 380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLSGKSQSL 9
           +LSG+ QSL
Sbjct: 127 SLSGRGQSL 135
>NP_001108446
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLSGKSQSL 9
           +LSG+ QSL
Sbjct: 127 SLSGRGQSL 135
>NP_775259
          Length = 931

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSG+S  L
Sbjct: 745 NLSGRSDKL 753
>NP_001028748
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSG+S  L
Sbjct: 743 NLSGRSDKL 751
>NP_001177203
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           +SGKSQ L
Sbjct: 139 VSGKSQDL 146
>NP_079409
          Length = 843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSGKSQSL 9
          +SGKSQ L
Sbjct: 55 VSGKSQDL 62
>NP_066958
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LSGKSQSL 9
           LSG++QSL
Sbjct: 282 LSGEAQSL 289
>NP_001006933
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LSGKSQSL 9
           LSG++QSL
Sbjct: 290 LSGEAQSL 297
>NP_001035282
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSGK + L
Sbjct: 219 NLSGKGKPL 227
>NP_060303
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSGK + L
Sbjct: 219 NLSGKGKPL 227
>XP_006725461
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSGK + L
Sbjct: 219 NLSGKGKPL 227
>XP_006724090
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           NLSGK + L
Sbjct: 219 NLSGKGKPL 227
>XP_005267149
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LSGKSQSL 9
           LSG++QSL
Sbjct: 307 LSGEAQSL 314
>XP_006715612
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LSGKSQSL 9
           LSG++QSL
Sbjct: 310 LSGEAQSL 317
>XP_005264631
          Length = 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           +SGKSQ L
Sbjct: 139 VSGKSQDL 146
>XP_005264630
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           +SGKSQ L
Sbjct: 139 VSGKSQDL 146
>XP_005264629
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           +SGKSQ L
Sbjct: 139 VSGKSQDL 146
>NP_006845
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSGKSQSL 9
          +SGKSQ L
Sbjct: 32 ISGKSQLL 39
>NP_001094073
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSGKSQSL 9
          +SGKSQ L
Sbjct: 32 ISGKSQLL 39
>NP_653299
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           +SGKSQ +
Sbjct: 800 MSGKSQEI 807
>NP_057839
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSGKSQSL 9
          +SGKSQ L
Sbjct: 32 ISGKSQIL 39
>NP_001267728
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           +SGKSQ +
Sbjct: 710 MSGKSQEI 717
>NP_006846
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSGKSQSL 9
          +SGKSQ L
Sbjct: 32 ISGKSQIL 39
>NP_002431
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSGKSQSL 9
           N+SGKS  L
Sbjct: 682 NMSGKSTYL 690
>NP_006792
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSGKSQSL 9
          +SGKSQ L
Sbjct: 32 ISGKSQVL 39
>NP_690607
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NLSGKSQ 7
          NLS KSQ
Sbjct: 34 NLSNKSQ 40
>NP_004972
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  NLSGKSQ 7
          NLS KSQ
Sbjct: 34 NLSNKSQ 40
>NP_001004740
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSGKSQSL 9
           LSG SQSL
Sbjct: 154 LSGFSQSL 161
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290    0.110    0.257 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 527,848
Number of extensions: 483
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package