Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_570711                                                              18    1935
NP_570712                                                              18    1935
NP_570714                                                              18    1935
NP_570713                                                              18    1935
NP_570716                                                              18    1935
NP_000235                                                              18    1935
NP_570715                                                              18    1935
XP_006718620                                                           18    1935
XP_005274059                                                           18    1935
XP_005274060                                                           18    1935
XP_005274058                                                           18    1935
NP_001135745                                                           17    4312
NP_001135746                                                           17    4312
NP_001193980                                                           17    4312
NP_056097                                                              17    4312
NP_055912                                                              17    4312
NP_001193973                                                           17    4312
NP_001273606                                                           17    4312
XP_006713123                                                           17    4312
XP_006713121                                                           17    4312
XP_006713120                                                           17    4312
XP_006713119                                                           17    4312
XP_006713118                                                           17    4312
XP_006713117                                                           17    4312
XP_006713116                                                           17    4312
XP_006713115                                                           17    4312
XP_006713114                                                           17    4312
XP_006713113                                                           17    4312
XP_006713112                                                           17    4312
XP_006713111                                                           17    4312
XP_006713110                                                           17    4312
XP_006713109                                                           17    4312
XP_006713108                                                           17    4312
XP_006713107                                                           17    4312
XP_006713106                                                           17    4312
XP_006713105                                                           17    4312
XP_006713104                                                           17    4312
XP_006713103                                                           17    4312
XP_006713102                                                           17    4312
XP_006713101                                                           17    4312
XP_006713100                                                           17    4312
XP_006713099                                                           17    4312
XP_006712448                                                           17    4312
XP_006712447                                                           17    4312
XP_006712446                                                           17    4312
XP_006712445                                                           17    4312
XP_006712444                                                           17    4312
XP_006712443                                                           17    4312
XP_006712442                                                           17    4312
XP_006712441                                                           17    4312
XP_006712440                                                           17    4312
XP_006712439                                                           17    4312
XP_006712438                                                           17    4312
XP_006712437                                                           17    4312
XP_006712436                                                           17    4312
NP_787074                                                              16    7355
NP_705838                                                              15    9605
NP_001229243                                                           15    9605
NP_004712                                                              15    9605
NP_001229246                                                           15    9605
NP_653294                                                              15    9605
XP_005259813                                                           15    9605
XP_005259812                                                           15    9605
>NP_570711
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 571 NSSAIKLQL 579
>NP_570712
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 576 NSSAIKLQL 584
>NP_570714
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 576 NSSAIKLQL 584
>NP_570713
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 576 NSSAIKLQL 584
>NP_570716
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 576 NSSAIKLQL 584
>NP_000235
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 576 NSSAIKLQL 584
>NP_570715
          Length = 615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 576 NSSAIKLQL 584
>XP_006718620
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 571 NSSAIKLQL 579
>XP_005274059
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 571 NSSAIKLQL 579
>XP_005274060
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 571 NSSAIKLQL 579
>XP_005274058
          Length = 610

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NLSAIKLQL 9
           N SAIKLQL
Sbjct: 571 NSSAIKLQL 579
>NP_001135745
          Length = 1479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1380 NLAAIKMQ 1387
>NP_001135746
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1372 NLAAIKMQ 1379
>NP_001193980
          Length = 1477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1378 NLAAIKMQ 1385
>NP_056097
          Length = 1538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1439 NLAAIKMQ 1446
>NP_055912
          Length = 1515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1416 NLAAIKMQ 1423
>NP_001193973
          Length = 1294

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1195 NLAAIKMQ 1202
>NP_001273606
          Length = 289

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NLSAIKLQ 8
           NLSA+KL+
Sbjct: 272 NLSALKLE 279
>XP_006713123
          Length = 1514

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1415 NLAAIKMQ 1422
>XP_006713121
          Length = 1286

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1187 NLAAIKMQ 1194
>XP_006713120
          Length = 1287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1188 NLAAIKMQ 1195
>XP_006713119
          Length = 1308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1209 NLAAIKMQ 1216
>XP_006713118
          Length = 1328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1229 NLAAIKMQ 1236
>XP_006713117
          Length = 1334

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1235 NLAAIKMQ 1242
>XP_006713116
          Length = 1507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1408 NLAAIKMQ 1415
>XP_006713115
          Length = 1514

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1415 NLAAIKMQ 1422
>XP_006713114
          Length = 1523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1424 NLAAIKMQ 1431
>XP_006713113
          Length = 1524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1425 NLAAIKMQ 1432
>XP_006713112
          Length = 1527

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1428 NLAAIKMQ 1435
>XP_006713111
          Length = 1532

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1433 NLAAIKMQ 1440
>XP_006713110
          Length = 1533

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1434 NLAAIKMQ 1441
>XP_006713109
          Length = 1537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1438 NLAAIKMQ 1445
>XP_006713108
          Length = 1541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1442 NLAAIKMQ 1449
>XP_006713107
          Length = 1544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1445 NLAAIKMQ 1452
>XP_006713106
          Length = 1545

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1446 NLAAIKMQ 1453
>XP_006713105
          Length = 1545

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1446 NLAAIKMQ 1453
>XP_006713104
          Length = 1552

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1453 NLAAIKMQ 1460
>XP_006713103
          Length = 1553

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1454 NLAAIKMQ 1461
>XP_006713102
          Length = 1554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1455 NLAAIKMQ 1462
>XP_006713101
          Length = 1561

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1462 NLAAIKMQ 1469
>XP_006713100
          Length = 1561

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1462 NLAAIKMQ 1469
>XP_006713099
          Length = 1562

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1463 NLAAIKMQ 1470
>XP_006712448
          Length = 1255

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1156 NLAAIKMQ 1163
>XP_006712447
          Length = 1264

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1165 NLAAIKMQ 1172
>XP_006712446
          Length = 1454

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1355 NLAAIKMQ 1362
>XP_006712445
          Length = 1462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1363 NLAAIKMQ 1370
>XP_006712444
          Length = 1470

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1371 NLAAIKMQ 1378
>XP_006712443
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1379 NLAAIKMQ 1386
>XP_006712442
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1379 NLAAIKMQ 1386
>XP_006712441
          Length = 1486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1387 NLAAIKMQ 1394
>XP_006712440
          Length = 1487

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1388 NLAAIKMQ 1395
>XP_006712439
          Length = 1487

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1388 NLAAIKMQ 1395
>XP_006712438
          Length = 1494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1395 NLAAIKMQ 1402
>XP_006712437
          Length = 1494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1395 NLAAIKMQ 1402
>XP_006712436
          Length = 1495

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    NLSAIKLQ 8
            NL+AIK+Q
Sbjct: 1396 NLAAIKMQ 1403
>NP_787074
          Length = 459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAIKLQL 9
           SA+KLQL
Sbjct: 323 SAVKLQL 329
>NP_705838
          Length = 4069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LSAIKLQL 9
            +SA+K+QL
Sbjct: 3542 ISAVKVQL 3549
>NP_001229243
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSAIKLQL 9
           LSAI LQL
Sbjct: 486 LSAIMLQL 493
>NP_004712
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSAIKLQL 9
           LSAI LQL
Sbjct: 486 LSAIMLQL 493
>NP_001229246
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSAIKLQL 9
           LSAI LQL
Sbjct: 279 LSAIMLQL 286
>NP_653294
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSAIKLQL 9
           NLSA+K  L
Sbjct: 359 NLSAVKKHL 367
>XP_005259813
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSAIKLQL 9
           NLSA+K  L
Sbjct: 288 NLSAVKKHL 296
>XP_005259812
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NLSAIKLQL 9
           NLSA+K  L
Sbjct: 359 NLSAVKKHL 367
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.132    0.307 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 315,618
Number of extensions: 451
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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