Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_055730                                                              17    4312
NP_001242982                                                           17    4312
XP_006717494                                                           17    4312
XP_006717493                                                           17    4312
XP_006717491                                                           17    4312
XP_006717490                                                           17    4312
XP_006717489                                                           17    4312
XP_006717488                                                           17    4312
XP_006717487                                                           17    4312
XP_006717486                                                           17    4312
NP_062551                                                              17    4312
NP_067585                                                              16    5631
NP_004318                                                              16    5631
NP_001243839                                                           16    5631
NP_722518                                                              16    5631
NP_001166173                                                           16    5631
NP_068749                                                              16    5631
NP_004719                                                              16    5631
XP_006720112                                                           16    5631
XP_006720110                                                           16    5631
XP_006720109                                                           16    5631
XP_005250581                                                           16    5631
NP_004659                                                              16    7355
NP_001253981                                                           16    7355
XP_005257983                                                           16    7355
XP_006719560                                                           16    7355
XP_005269075                                                           16    7355
XP_006716232                                                           16    7355
XP_006716231                                                           16    7355
NP_775259                                                              16    7355
NP_001028748                                                           16    7355
NP_060458                                                              16    7355
NP_001243092                                                           15    9605
NP_001243095                                                           15    9605
NP_001157                                                              15    9605
NP_003900                                                              15    9605
NP_653309                                                              15    9605
NP_061863                                                              15    9605
NP_114425                                                              15    9605
NP_998890                                                              15    9605
NP_000994                                                              15    9605
NP_003667                                                              15    9605
XP_006724826                                                           15    9605
XP_005251150                                                           15    9605
XP_006711902                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1151 NLLNANVDS 1159
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1151 NLLNANVDS 1159
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1161 NLLNANVDS 1169
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1161 NLLNANVDS 1169
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1161 NLLNANVDS 1169
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1151 NLLNANVDS 1159
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1161 NLLNANVDS 1169
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1161 NLLNANVDS 1169
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1148 NLLNANVDS 1156
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1151 NLLNANVDS 1159
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NLLNANVGS 9
            NLLNANV S
Sbjct: 1161 NLLNANVDS 1169
>NP_055730
          Length = 1710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1318 NLLNANL 1324
>NP_001242982
          Length = 1709

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1317 NLLNANL 1323
>XP_006717494
          Length = 1571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1179 NLLNANL 1185
>XP_006717493
          Length = 1610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1218 NLLNANL 1224
>XP_006717491
          Length = 1677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1285 NLLNANL 1291
>XP_006717490
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1399 NLLNANL 1405
>XP_006717489
          Length = 1945

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1680 NLLNANL 1686
>XP_006717488
          Length = 2031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1680 NLLNANL 1686
>XP_006717487
          Length = 2071

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1679 NLLNANL 1685
>XP_006717486
          Length = 2072

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    NLLNANV 7
            NLLNAN+
Sbjct: 1680 NLLNANL 1686
>NP_062551
          Length = 356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LNANVGS 9
           +NANVGS
Sbjct: 206 VNANVGS 212
>NP_067585
          Length = 1227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLLNANVGS 9
           NL++AN GS
Sbjct: 259 NLIDANGGS 267
>NP_004318
          Length = 1271

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLLNANVGS 9
           NL++AN GS
Sbjct: 259 NLIDANGGS 267
>NP_001243839
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NLLNANVG 8
           +L+N+NVG
Sbjct: 560 SLINSNVG 567
>NP_722518
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NL+NA +GS
Sbjct: 53 NLMNAIMGS 61
>NP_001166173
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NL+NA +GS
Sbjct: 53 NLMNAIMGS 61
>NP_068749
          Length = 792

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLNANVGS 9
           +LN NVGS
Sbjct: 736 VLNLNVGS 743
>NP_004719
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NLLNANVG 8
           +L+N+NVG
Sbjct: 628 SLINSNVG 635
>XP_006720112
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NL+NA +GS
Sbjct: 53 NLMNAIMGS 61
>XP_006720110
          Length = 433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NL+NA +GS
Sbjct: 30 NLMNAIMGS 38
>XP_006720109
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NL+NA +GS
Sbjct: 53 NLMNAIMGS 61
>XP_005250581
          Length = 451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLNANVGS 9
           +LN NVGS
Sbjct: 395 VLNLNVGS 402
>NP_004659
          Length = 1857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   NLLNANVG 8
           NL+N N G
Sbjct: 143 NLVNTNAG 150
>NP_001253981
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLLN NV
Sbjct: 301 NLLNKNV 307
>XP_005257983
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLLN NV
Sbjct: 301 NLLNKNV 307
>XP_006719560
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NLLNANVG 8
           N LNAN+G
Sbjct: 668 NGLNANMG 675
>XP_005269075
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NLLNANVG 8
           N LNAN+G
Sbjct: 771 NGLNANMG 778
>XP_006716232
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   NLLNANVG 8
           NL+N N G
Sbjct: 143 NLVNTNAG 150
>XP_006716231
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   NLLNANVG 8
           NL+N N G
Sbjct: 143 NLVNTNAG 150
>NP_775259
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLLN NV
Sbjct: 301 NLLNKNV 307
>NP_001028748
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLLN NV
Sbjct: 301 NLLNKNV 307
>NP_060458
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NLLNANVG 8
           N LNAN+G
Sbjct: 771 NGLNANMG 778
>NP_001243092
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NLLNANVGS 9
           NL++A++GS
Sbjct: 115 NLVSASLGS 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLL ANV
Sbjct: 481 NLLKANV 487
>NP_001243095
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  NLLNANVGS 9
          NL++A++GS
Sbjct: 66 NLVSASLGS 74

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLL ANV
Sbjct: 432 NLLKANV 438
>NP_001157
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NLLNANVGS 9
           NL++A++GS
Sbjct: 115 NLVSASLGS 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLL ANV
Sbjct: 481 NLLKANV 487
>NP_003900
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NLL+ ++GS
Sbjct: 17 NLLDKDIGS 25
>NP_653309
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NLLNANV 7
           NLLN N+
Sbjct: 830 NLLNLNI 836
>NP_061863
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLNANVGS 9
           LLN  VGS
Sbjct: 216 LLNGKVGS 223
>NP_114425
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          N+L A+VGS
Sbjct: 76 NILLASVGS 84
>NP_998890
          Length = 89

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LLNANVGS 9
          L N N+GS
Sbjct: 26 LANVNIGS 33
>NP_000994
          Length = 114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LLNANVGS 9
          L N N+GS
Sbjct: 51 LANVNIGS 58
>NP_003667
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NLLNANVG 8
           NLL  NVG
Sbjct: 250 NLLTFNVG 257
>XP_006724826
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLNANVGS 9
           LLN  VGS
Sbjct: 266 LLNGKVGS 273
>XP_005251150
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  NLLNANVGS 9
          NLL+ ++GS
Sbjct: 17 NLLDKDIGS 25
>XP_006711902
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NLLNANVG 8
           NLL  NVG
Sbjct: 250 NLLTFNVG 257
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.124    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 412,321
Number of extensions: 798
Number of successful extensions: 59
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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