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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     665
XP_006718907                                                           19     665
XP_006718906                                                           19     665
XP_005271619                                                           19     665
XP_005271618                                                           19     665
NP_061836                                                              17    3301
NP_387505                                                              17    3301
XP_005261051                                                           17    3301
NP_001690                                                              17    4312
NP_001265528                                                           17    4312
NP_068713                                                              17    4312
NP_954657                                                              16    5631
NP_000215                                                              16    5631
NP_001243352                                                           16    5631
NP_116289                                                              16    5631
NP_001191229                                                           16    5631
NP_001273034                                                           16    7355
NP_001273038                                                           16    7355
NP_001273039                                                           16    7355
NP_001273033                                                           16    7355
NP_001035897                                                           16    7355
NP_000077                                                              16    7355
NP_055472                                                              16    7355
XP_005260678                                                           16    7355
NP_060873                                                              15    9605
NP_001277134                                                           15    9605
NP_001277133                                                           15    9605
NP_055543                                                              15    9605
XP_006724587                                                           15    9605
XP_005274689                                                           15    9605
NP_001011719                                                           15    9605

>NP_000042
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NLIKLMADI 9
           NLI+LMADI
Sbjct: 344 NLIELMADI 352



>XP_006718907
          Length = 3050

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NLIKLMADI 9
           NLI+LMADI
Sbjct: 344 NLIELMADI 352



>XP_006718906
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NLIKLMADI 9
           NLI+LMADI
Sbjct: 344 NLIELMADI 352



>XP_005271619
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NLIKLMADI 9
           NLI+LMADI
Sbjct: 344 NLIELMADI 352



>XP_005271618
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NLIKLMADI 9
           NLI+LMADI
Sbjct: 344 NLIELMADI 352



>NP_061836
          Length = 2320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NLIKLMADI 9
            N IKLM+D+
Sbjct: 1638 NKIKLMSDV 1646




 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NLIKLMADI 9
            N IKLM+D+
Sbjct: 1937 NKIKLMSDV 1945



>NP_387505
          Length = 2269

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NLIKLMADI 9
            N IKLM+D+
Sbjct: 1638 NKIKLMSDV 1646




 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NLIKLMADI 9
            N IKLM+D+
Sbjct: 1937 NKIKLMSDV 1945



>XP_005261051
          Length = 2242

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NLIKLMADI 9
            N IKLM+D+
Sbjct: 1560 NKIKLMSDV 1568




 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NLIKLMADI 9
            N IKLM+D+
Sbjct: 1859 NKIKLMSDV 1867



>NP_001690
          Length = 885

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LIKLMADI 9
           L+K MADI
Sbjct: 640 LVKFMADI 647



>NP_001265528
          Length = 626

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LIKLMADI 9
           L+K MADI
Sbjct: 381 LVKFMADI 388



>NP_068713
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LIKLMADI 9
           L+K MADI
Sbjct: 649 LVKFMADI 656



>NP_954657
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           +L K+MADI
Sbjct: 244 DLAKIMADI 252



>NP_000215
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           +L K+MADI
Sbjct: 244 DLAKIMADI 252



>NP_001243352
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+KL+ D+
Sbjct: 232 NLLKLLLDL 240



>NP_116289
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+KL+ D+
Sbjct: 241 NLLKLLLDL 249



>NP_001191229
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+KL+ D+
Sbjct: 241 NLLKLLLDL 249



>NP_001273034
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 255 NLVFLLADV 263



>NP_001273038
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 277 NLVFLLADV 285



>NP_001273039
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 301 NLVFLLADV 309



>NP_001273033
          Length = 414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 331 NLVFLLADV 339



>NP_001035897
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 355 NLVFLLADV 363



>NP_000077
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 355 NLVFLLADV 363



>NP_055472
          Length = 1089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 729 NLLPLVADV 737



>XP_005260678
          Length = 1089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NLIKLMADI 9
           NL+ L+AD+
Sbjct: 729 NLLPLVADV 737



>NP_060873
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LIKLMADI 9
           + KLMAD+
Sbjct: 118 IAKLMADV 125



>NP_001277134
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LIKLMADI 9
          + KLMAD+
Sbjct: 46 IAKLMADV 53



>NP_001277133
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LIKLMADI 9
           + KLMAD+
Sbjct: 118 IAKLMADV 125



>NP_055543
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NLIKLMAD 8
           NL+ L+AD
Sbjct: 456 NLVALLAD 463



>XP_006724587
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NLIKLMAD 8
           NL+ L+AD
Sbjct: 426 NLVALLAD 433



>XP_005274689
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NLIKLMAD 8
           NL+ L+AD
Sbjct: 456 NLVALLAD 463



>NP_001011719
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  NLIKLMAD 8
          N++ LMAD
Sbjct: 8  NIVLLMAD 15



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.148    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 312,863
Number of extensions: 574
Number of successful extensions: 34
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)