Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     869
NP_001075109                                                           19     869
NP_892006                                                              17    3301
NP_149062                                                              17    3301
XP_006715488                                                           17    3301
XP_006715487                                                           17    3301
XP_006715486                                                           17    3301
XP_006715485                                                           17    3301
XP_006715484                                                           17    3301
XP_006715483                                                           17    3301
XP_006715482                                                           17    3301
XP_006715481                                                           17    3301
XP_006715480                                                           17    3301
XP_006715479                                                           17    3301
XP_006715478                                                           17    3301
XP_006715477                                                           17    3301
XP_006715476                                                           17    3301
XP_006715475                                                           17    3301
XP_006715474                                                           17    3301
XP_006715473                                                           17    3301
XP_006715472                                                           17    3301
XP_006715471                                                           17    3301
XP_006715470                                                           17    3301
NP_005489                                                              16    7355
XP_005259758                                                           16    7355
XP_005264359                                                           16    7355
NP_001073943                                                           16    7355
NP_000171                                                              15    9605
NP_001018098                                                           15    9605
NP_060154                                                              15    9605
NP_060550                                                              15    9605
NP_065872                                                              15    9605
NP_001239542                                                           15    9605
NP_036533                                                              15    9605
NP_001239541                                                           15    9605
NP_001014972                                                           15    9605
NP_055312                                                              15    9605
XP_005261968                                                           15    9605
XP_005261966                                                           15    9605
XP_005261967                                                           15    9605
XP_006724476                                                           15    9605
XP_005261965                                                           15    9605
XP_005264321                                                           15    9605
XP_006712053                                                           15    9605
XP_005264320                                                           15    9605
XP_006712052                                                           15    9605
XP_005264319                                                           15    9605
XP_005264318                                                           15    9605



>NP_008835
          Length = 4128

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NKAISLEEI 9
           N+AISLEEI
Sbjct: 843 NEAISLEEI 851





>NP_001075109
          Length = 4097

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NKAISLEEI 9
           N+AISLEEI
Sbjct: 843 NEAISLEEI 851





>NP_892006
          Length = 8797

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2246 NKALRLEEL 2254





>NP_149062
          Length = 8749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715488
          Length = 8721

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715487
          Length = 8744

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715486
          Length = 8758

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715485
          Length = 8793

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2200 NKALRLEEL 2208





>XP_006715484
          Length = 8794

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715483
          Length = 8795

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715482
          Length = 8797

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2246 NKALRLEEL 2254





>XP_006715481
          Length = 8799

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2206 NKALRLEEL 2214





>XP_006715480
          Length = 8799

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715479
          Length = 8804

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715478
          Length = 8809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715477
          Length = 8822

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2229 NKALRLEEL 2237





>XP_006715476
          Length = 8823

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715475
          Length = 8827

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715474
          Length = 8829

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2236 NKALRLEEL 2244





>XP_006715473
          Length = 8832

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715472
          Length = 8839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2246 NKALRLEEL 2254





>XP_006715471
          Length = 8842

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>XP_006715470
          Length = 8846

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NKAISLEEI 9
            NKA+ LEE+
Sbjct: 2253 NKALRLEEL 2261





>NP_005489
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NKAISLEEI 9
           NK++ LE++
Sbjct: 228 NKSVELEDV 236





>XP_005259758
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NKAISLEEI 9
           NK++ LE++
Sbjct: 230 NKSVELEDV 238





>XP_005264359
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NKAISLEE 8
           NK++SLE+
Sbjct: 420 NKSLSLED 427





>NP_001073943
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NKAISLEE 8
           NK++SLE+
Sbjct: 420 NKSLSLED 427





>NP_000171
          Length = 1103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    NKAISLEEI 9
            N  ISL+EI
Sbjct: 1078 NHGISLQEI 1086





>NP_001018098
          Length = 3628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK + LE+I
Sbjct: 651 NKGLDLEQI 659





>NP_060154
          Length = 3710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK + LE+I
Sbjct: 608 NKGLDLEQI 616





>NP_060550
          Length = 3585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK + LE+I
Sbjct: 608 NKGLDLEQI 616





>NP_065872
          Length = 3753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK + LE+I
Sbjct: 651 NKGLDLEQI 659





>NP_001239542
          Length = 1957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 914 NKGYSVEEV 922





>NP_036533
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NKAISLEE 8
            NKA++L+E
Sbjct: 1120 NKAMTLQE 1127





>NP_001239541
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 914 NKGYSVEEV 922





>NP_001014972
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 914 NKGYSVEEV 922





>NP_055312
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 914 NKGYSVEEV 922





>XP_005261968
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NKAISLEE 8
            NKA++L+E
Sbjct: 1120 NKAMTLQE 1127





>XP_005261966
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NKAISLEE 8
            NKA++L+E
Sbjct: 1120 NKAMTLQE 1127





>XP_005261967
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NKAISLEE 8
            NKA++L+E
Sbjct: 1120 NKAMTLQE 1127





>XP_006724476
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NKAISLEE 8
            NKA++L+E
Sbjct: 1120 NKAMTLQE 1127





>XP_005261965
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    NKAISLEE 8
            NKA++L+E
Sbjct: 1202 NKAMTLQE 1209





>XP_005264321
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NKAISLEEI 9
            NK  S+EE+
Sbjct: 1020 NKGYSVEEV 1028





>XP_006712053
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 403 NKGYSVEEV 411





>XP_005264320
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 403 NKGYSVEEV 411





>XP_006712052
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NKAISLEEI 9
           NK  S+EE+
Sbjct: 403 NKGYSVEEV 411





>XP_005264319
          Length = 2049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NKAISLEEI 9
            NK  S+EE+
Sbjct: 1020 NKGYSVEEV 1028





>XP_005264318
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NKAISLEEI 9
            NK  S+EE+
Sbjct: 1020 NKGYSVEEV 1028





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.123    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 481,162
Number of extensions: 679
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package