Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060719                                                              18    1482
NP_001258968                                                           18    1482
NP_001011649                                                           18    1482
NP_001185761                                                           18    1482
NP_071754                                                              18    1482
NP_001185763                                                           18    1482
NP_001002810                                                           18    1482
NP_055459                                                              18    1482
NP_008893                                                              18    1482
NP_001171570                                                           18    1482
NP_001007089                                                           18    1482
NP_001182189                                                           18    1482
NP_001002812                                                           18    1482
NP_001182190                                                           18    1482
XP_006717248                                                           18    1482
XP_006717247                                                           18    1482
XP_006717246                                                           18    1482
XP_006717245                                                           18    1482
XP_006717244                                                           18    1482
XP_006717243                                                           18    1482
XP_006717242                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
NP_079524                                                              17    4312
XP_006725425                                                           17    4312
XP_006725424                                                           17    4312
XP_006725423                                                           17    4312
XP_006725422                                                           17    4312
XP_006725421                                                           17    4312
XP_006725420                                                           17    4312
XP_006725419                                                           17    4312
XP_006722186                                                           17    4312
XP_006722185                                                           17    4312
XP_006722184                                                           17    4312
XP_006722183                                                           17    4312
XP_006722182                                                           17    4312
XP_006722181                                                           17    4312
XP_006722180                                                           17    4312
NP_005427                                                              16    5631
NP_056509                                                              16    7355
XP_005250038                                                           16    7355
XP_005250037                                                           16    7355
NP_055383                                                              15    9605
NP_037522                                                              15    9605
NP_001129292                                                           15    9605
NP_056163                                                              15    9605
XP_005276568                                                           15    9605
XP_005276567                                                           15    9605
XP_005255280                                                           15    9605
XP_006717096                                                           15    9605
XP_005251926                                                           15    9605
XP_005263969                                                           15    9605
XP_005263968                                                           15    9605
XP_005263967                                                           15    9605
XP_005263966                                                           15    9605
NP_055113                                                              15    9605
>NP_060719
          Length = 1893

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>NP_001258968
          Length = 1663

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>NP_001011649
          Length = 1814

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 114 NIELKVEVE 122
>NP_071754
          Length = 310

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 185 NIELKVEVE 193
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 48 NIELKVEVE 56
>NP_001002810
          Length = 173

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 48 NIELKVEVE 56
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 48 NIELKVEVE 56
>NP_008893
          Length = 639

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  NIVLKVEVE 9
          N++LK+EVE
Sbjct: 74 NLILKLEVE 82
>NP_001171570
          Length = 639

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  NIVLKVEVE 9
          N++LK+EVE
Sbjct: 74 NLILKLEVE 82
>NP_001007089
          Length = 620

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  NIVLKVEVE 9
          N++LK+EVE
Sbjct: 55 NLILKLEVE 63
>NP_001182189
          Length = 141

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 16 NIELKVEVE 24
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 48 NIELKVEVE 56
>NP_001182190
          Length = 176

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 51 NIELKVEVE 59
>XP_006717248
          Length = 1664

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>XP_006717247
          Length = 1670

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>XP_006717246
          Length = 1820

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>XP_006717245
          Length = 1861

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>XP_006717244
          Length = 1867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 103 NIELKVEVE 111
>XP_006717243
          Length = 1889

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 93  NIELKVEVE 101
>XP_006717242
          Length = 1898

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 102 NIELKVEVE 110
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 114 NIELKVEVE 122
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 114 NIELKVEVE 122
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 114 NIELKVEVE 122
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 48 NIELKVEVE 56
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 48 NIELKVEVE 56
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          NI LKVEVE
Sbjct: 51 NIELKVEVE 59
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 114 NIELKVEVE 122
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NI LKVEVE
Sbjct: 114 NIELKVEVE 122
>NP_079524
          Length = 1183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 789 VVLRVEVE 796
>XP_006725425
          Length = 1035

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 643 VVLRVEVE 650
>XP_006725424
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 643 VVLRVEVE 650
>XP_006725423
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 643 VVLRVEVE 650
>XP_006725422
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 740 VVLRVEVE 747
>XP_006725421
          Length = 1132

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 740 VVLRVEVE 747
>XP_006725420
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 699 VVLRVEVE 706
>XP_006725419
          Length = 1175

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 740 VVLRVEVE 747
>XP_006722186
          Length = 1035

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 643 VVLRVEVE 650
>XP_006722185
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 643 VVLRVEVE 650
>XP_006722184
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 643 VVLRVEVE 650
>XP_006722183
          Length = 1091

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 740 VVLRVEVE 747
>XP_006722182
          Length = 1132

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 740 VVLRVEVE 747
>XP_006722181
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 699 VVLRVEVE 706
>XP_006722180
          Length = 1175

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           +VL+VEVE
Sbjct: 740 VVLRVEVE 747
>NP_005427
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  NIVLKVEVE 9
          N VLK+E+E
Sbjct: 70 NKVLKIELE 78
>NP_056509
          Length = 831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           IV+K+EV+
Sbjct: 367 IVIKIEVQ 374
>XP_005250038
          Length = 831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           IV+K+EV+
Sbjct: 367 IVIKIEVQ 374
>XP_005250037
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IVLKVEVE 9
           IV+K+EV+
Sbjct: 411 IVIKIEVQ 418
>NP_055383
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLKVEVE 9
           VLKVEV+
Sbjct: 98  VLKVEVD 104
>NP_037522
          Length = 1383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NIV++ EVE
Sbjct: 491 NIVIQGEVE 499
>NP_001129292
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NIV++ EVE
Sbjct: 428 NIVIQGEVE 436
>NP_056163
          Length = 1883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVLKVEVE 9
           I+L VEVE
Sbjct: 308 IILPVEVE 315
>XP_005276568
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NIVLKVEVE 9
           +  LKVEVE
Sbjct: 193 DFALKVEVE 201
>XP_005276567
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NIVLKVEVE 9
           +  LKVEVE
Sbjct: 194 DFALKVEVE 202
>XP_005255280
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NIVLKVEVE 9
           +  LKVEVE
Sbjct: 194 DFTLKVEVE 202
>XP_006717096
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NIV++ EVE
Sbjct: 491 NIVIQGEVE 499
>XP_005251926
          Length = 1383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NIVLKVEVE 9
           NIV++ EVE
Sbjct: 491 NIVIQGEVE 499
>XP_005263969
          Length = 1844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVLKVEVE 9
           I+L VEVE
Sbjct: 269 IILPVEVE 276
>XP_005263968
          Length = 1861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVLKVEVE 9
           I+L VEVE
Sbjct: 286 IILPVEVE 293
>XP_005263967
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVLKVEVE 9
           I+L VEVE
Sbjct: 325 IILPVEVE 332
>XP_005263966
          Length = 1900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVLKVEVE 9
           I+L VEVE
Sbjct: 325 IILPVEVE 332
>NP_055113
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NIVLKVEVE 9
           +  LKVEVE
Sbjct: 193 DFALKVEVE 201
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.137    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 372,374
Number of extensions: 681
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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